Journal
CATALYSTS
Volume 11, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/catal11091103
Keywords
Lewis base catalysis; trichlorosilane; hydrosilylation; hydrazone; computational chemistry
Categories
Funding
- National Institute of Health [1R15 GM139087-01]
- Florida Institute of Technology
Ask authors/readers for more resources
A new class of axial-chiral biisoquinoline N,N'-dioxides was evaluated as catalysts for the enantioselective hydrosilylation of acyl hydrazones with trichlorosilane. Although these catalysts showed poor to moderate reactivity and enantioselectivity, this study represents the first example of organocatalytic asymmetric reduction of acyl hydrazones. Additionally, the structures and energies of two possible diastereomeric catalyst-trichlorosilane complexes were analyzed using density functional theory calculations.
A new class of axial-chiral biisoquinoline N,N '-dioxides was evaluated as catalysts for the enantioselective hydrosilylation of acyl hydrazones with trichlorosilane. While these catalysts provided poor to moderate reactivity and enantioselectivity, this study represents the first example of the organocatalytic asymmetric reduction of acyl hydrazones. In addition, the structures and energies of two possible diastereomeric catalyst-trichlorosilane complexes (2a-HSiCl3) were analyzed using density functional theory calculations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available