Advances in topiramate as prophylactic treatment for migraine

It is well-known that topiramate as a kind of antiepileptic drug has been proved effective for migraine prevention in North America and Europe. However, topiramate is still viewed as an off-label medication for migraine treatment in China, partly because of the limited evidence in Chinese patients. We summarize the effects of topiramate on the frequency, severity, quality-of-life, and adverse event among migraine patients, including children and adolescent in this review, so as to provide reference for Chinese doctors.

Automated summary

Topiramate has been proven effective for migraine prevention in North America and Europe, but is still considered an off-label medication for migraine treatment in China due to limited evidence. This review summarizes the effects of topiramate on migraine patients in China, providing reference for Chinese doctors.