Journal
MICROMACHINES
Volume 12, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/mi12080876
Keywords
ultrasonic particle manipulation; acoustic tweezers; acoustic radiation force; acoustic streaming; glass capillary; miniaturized ultrasonic devices
Categories
Funding
- National Natural Science Foundation of China [11804060, 51975131]
- Natural Science Foundation of Guangdong Province [2021A1515010244]
- Guangzhou Basic and Applied Basic Research Foundation [202102020414]
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This review provides a comprehensive overview of ultrasonic particle manipulation (UPM) and its application in the field of microfluidics, with a focus on the design and operation mechanism of glass capillaries. The study also demonstrates the potential advantages and future prospects of glass capillaries in UPM.
Ultrasonic particle manipulation (UPM), a non-contact and label-free method that uses ultrasonic waves to manipulate micro- or nano-scale particles, has recently gained significant attention in the microfluidics community. Moreover, glass is optically transparent and has dimensional stability, distinct acoustic impedance to water and a high acoustic quality factor, making it an excellent material for constructing chambers for ultrasonic resonators. Over the past several decades, glass capillaries are increasingly designed for a variety of UPMs, e.g., patterning, focusing, trapping and transporting of micron or submicron particles. Herein, we review established and emerging glass capillary-transducer devices, describing their underlying mechanisms of operation, with special emphasis on the application of glass capillaries with fluid channels of various cross-sections (i.e., rectangular, square and circular) on UPM. We believe that this review will provide a superior guidance for the design of glass capillary-based UPM devices for acoustic tweezers-based research.
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