4.6 Article

Novel Blood Clot Retriever for Ischemic Stroke

Journal

MICROMACHINES
Volume 12, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/mi12080928

Keywords

ischemic stroke; blood clot retriever; medical device; Nitinol alloy; finite element analysis

Funding

  1. Ministry of Science and Technology in Taiwan [MOST-110-2622-E-002-028, MOST-108-2221-E-002-153-MY3]
  2. MOST

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Stroke is the second leading cause of death in the world, with ischemic stroke accounting for approximately 80% of cases. A unique blood clot retriever design was proposed for treating acute ischemic stroke, showing a retrieval rate of 79% and demonstrating the feasibility of the new design concept.
Stroke is the second leading cause of death in the world. Ischemic stroke, caused by the blockage of intracranial arteries, accounts for approximately 80% of strokes. Among this proportion, acute ischemic stroke, usually caused by the sudden formation of blood clots, can cause fatal blockages in arteries. We proposed a unique blood clot retriever for the treatment of acute ischemic stroke, and conducted a series of tasks, including design, computer simulation, prototyping, and bench testing, for the proof of concept. Unlike most blood clot retrievers used today, our novel design deviates from traditional stent-like blood clot retrievers and uses large closed cells, irregular spikes, and strut protrusions to achieve maximum entanglement for better retrieval performance. Experimental results showed that the retrieval rate of our blood clot retriever was 79%, which demonstrated the feasibility of our new design concept.

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