Journal
POLYMERS
Volume 13, Issue 13, Pages -Publisher
MDPI
DOI: 10.3390/polym13132102
Keywords
wound dressings; bioactive agents; hyaluronic acid; wound management
Categories
Funding
- Medical Research Council, Govan Mbeki Research and Development Centre, University of Fort Hare
- National Research Foundation, South Africa
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The negative factors that lead to delayed and prolonged wound healing, such as microbial pathogens and excess wound exudates, pose challenges for currently used wound dressings, necessitating improvements. Biopolymers offer interesting properties suitable for the design of wound dressings.
The negative factors that result in delayed and prolonged wound healing process include microbial pathogens, excess wound exudates, underlying conditions, smoking, obesity, etc. Most of the currently used wound dressings demonstrate an inadequate capacity to treat wounds resulting from the factors mentioned above. The commonly used wound dressings include hydrogels, films, hydrocolloids, foams, fibers, sponges, dermal patches, bandages, etc. These wound dressings can be loaded with various types of bioactive agents (e.g., antibiotics, nanoparticles, anti-inflammatory drugs, etc.) to improve their therapeutic outcomes. Biopolymers offer interesting properties suitable for the design of wound dressings. This review article will be based on hyaluronic-acid-based scaffolds loaded with therapeutic agents for the treatment of wounds.
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