4.7 Review

A Critical Review on Polymeric Biomaterials for Biomedical Applications

Journal

POLYMERS
Volume 13, Issue 17, Pages -

Publisher

MDPI
DOI: 10.3390/polym13173015

Keywords

smart biomaterials; tissue engineering; polymers; hydrogels; shape memory; 3D printing

Funding

  1. Department of Biotechnology, Government of India, through DBT-RA program [DBT-RA/2021/January/N/347]
  2. Department of Biotechnology, Government of India, through Ramalingaswami Re-entry fellowship [BT/HRD/35/02/2006]

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This review summarizes recent advancements in the preparation of smart polymeric biomaterials with self-healing and shape memory properties. It also discusses novel approaches for developing various forms of polymeric biomaterials and highlights their applications in soft and hard tissue engineering. It underlines the future directions of polymeric biomaterials for successful clinical implications.
Natural and synthetic polymers have been explored for many years in the field of tissue engineering and regeneration. Researchers have developed many new strategies to design successful advanced polymeric biomaterials. In this review, we summarized the recent notable advancements in the preparation of smart polymeric biomaterials with self-healing and shape memory properties. We also discussed novel approaches used to develop different forms of polymeric biomaterials such as films, hydrogels and 3D printable biomaterials. In each part, the applications of the biomaterials in soft and hard tissue engineering with their in vitro and in vivo effects are underlined. The future direction of the polymeric biomaterials that could pave a path towards successful clinical implications is also underlined in this review.

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