4.7 Article

Preparation and Performance Evaluation of Antibacterial Melt-Spun Polyurethane Fiber Loaded with Berberine Hydrochloride

Journal

POLYMERS
Volume 13, Issue 14, Pages -

Publisher

MDPI
DOI: 10.3390/polym13142336

Keywords

berberine hydrochloride; melt-spun polyurethane fiber; surface coating; antibacterial property

Funding

  1. National Natural Science Foundation of China [51803128, 52073186]
  2. Fundamental Re-search Funds for the Central Universities [20826041D4160]
  3. Sichuan Science and Technology Programs [2020KJT0031-2020ZHCG0051, 2020KJT0061-2020ZH FP0148]
  4. Strategic Project of Zi Gong Science& Technology Bureau [2019CDZG-S15]
  5. Sichuan University [2020SCUNG122]

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This study verified the application prospects of berberine hydrochloride in antibacterial fibers, the coating modified polyurethane fiber showed good antibacterial properties, mechanical properties, and surface wettability, and is expected to be applied in the biomedical field.
(1) Background: Bacterial infections have long threatened global public safety; hence, it is significant to continuously develop antibacterial fibers that are closely related to people's daily lives. Berberine hydrochloride is a natural antibacterial agent that has application prospects in the preparation of antibacterial fibers. (2) Methods: This study firstly verified the antibacterial properties of berberine hydrochloride and its possible antibacterial mechanism. Thereafter, berberine hydrochloride was introduced into the self-made melt-spun polyurethane fiber through optimized coating technology. The performance of coating modified polyurethane fiber has been systematically evaluated, including its antibacterial properties, mechanical properties, and surface wettability. (3) Results: Results show that the antibacterial polyurethane fiber with desirable comprehensive properties is expected to be used in the biomedical fields. (4) Conclusions: The research also provides a reference for the development and application of other natural antibacterial ingredients in fiber fields.

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