4.3 Article

Resetting the bar: Statistical significance in whole-genome sequencing-based association studies of global populations

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants

Joao Fadista et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2016)

Article Genetics & Heredity

Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set

Masahiro Kanai et al.

JOURNAL OF HUMAN GENETICS (2016)

Article Genetics & Heredity

Addressing Population-Specific Multiple Testing Burdens in Genetic Association Studies

Rafal S. Sobota et al.

ANNALS OF HUMAN GENETICS (2015)

Article Multidisciplinary Sciences

A global reference for human genetic variation

David M. Altshuler et al.

NATURE (2015)

Editorial Material Biochemical Research Methods

Successful test launch for nanopore sequencing

Nicholas J. Loman et al.

NATURE METHODS (2015)

Review Genetics & Heredity

Rare-Variant Association Analysis: Study Designs and Statistical Tests

Seunggeung Lee et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2014)

Article Genetics & Heredity

Estimating Genome-Wide Significance for Whole-Genome Sequencing Studies

ChangJiang Xu et al.

GENETIC EPIDEMIOLOGY (2014)

Article Multidisciplinary Sciences

Guidelines for investigating causality of sequence variants in human disease

D. G. MacArthur et al.

NATURE (2014)

News Item Multidisciplinary Sciences

The $1,000 genome

Erika Check Hayden

NATURE (2014)

Article Genetics & Heredity

Whole-genome sequence variation, population structure and demographic history of the Dutch population

Laurent C. Francioli et al.

NATURE GENETICS (2014)

Article Biochemistry & Molecular Biology

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

Danielle Welter et al.

NUCLEIC ACIDS RESEARCH (2014)

Review Genetics & Heredity

Association Claims in the Sequencing Era

Sara L. Pulit et al.

GENES (2014)

Article Biochemical Research Methods

Genotype calling and phasing using next-generation sequencing reads and a haplotype scaffold

Androniki Menelaou et al.

BIOINFORMATICS (2013)

News Item Multidisciplinary Sciences

3 WAYS TO BLOW THE WHISTLE

Ed Yong et al.

NATURE (2013)

Article Genetics & Heredity

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

Jacob Gratten et al.

NATURE GENETICS (2013)

Editorial Material Neurosciences

Raising standards

[Anonymous]

NATURE NEUROSCIENCE (2013)

Review Genetics & Heredity

Sequencing studies in human genetics: design and interpretation

David B. Goldstein et al.

NATURE REVIEWS GENETICS (2013)

Editorial Material Multidisciplinary Sciences

The time is right to confront misconduct

Colin Macilwain

NATURE (2012)

Article Multidisciplinary Sciences

An integrated map of genetic variation from 1,092 human genomes

David M. Altshuler et al.

NATURE (2012)

Article Genetics & Heredity

Exome sequencing and the genetic basis of complex traits

Adam Kiezun et al.

NATURE GENETICS (2012)

Article Multidisciplinary Sciences

A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

Daniel G. MacArthur et al.

SCIENCE (2012)

Article Biochemical Research Methods

HAPGEN2: simulation of multiple disease SNPs

Zhan Su et al.

BIOINFORMATICS (2011)

Article Genetics & Heredity

Identification of low-frequency variants associated with gout and serum uric acid levels

Patrick Sulem et al.

NATURE GENETICS (2011)

Article Genetics & Heredity

A framework for variation discovery and genotyping using next-generation DNA sequencing data

Mark A. DePristo et al.

NATURE GENETICS (2011)

Article Biotechnology & Applied Microbiology

The functional spectrum of low-frequency coding variation

Gabor T. Marth et al.

GENOME BIOLOGY (2011)

Article Biochemistry & Molecular Biology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna et al.

GENOME RESEARCH (2010)

Article Multidisciplinary Sciences

Integrating common and rare genetic variation in diverse human populations

David M. Altshuler et al.

NATURE (2010)

Review Genetics & Heredity

Genome-wide association studies in diverse populations

Noah A. Rosenberg et al.

NATURE REVIEWS GENETICS (2010)

Article Multidisciplinary Sciences

Multiethnic Genetic Association Studies Improve Power for Locus Discovery

Sara L. Pulit et al.

PLOS ONE (2010)

Article Multidisciplinary Sciences

Power of deep, all-exon resequencing for discovery of human trait genes

Gregory V. Kryukov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Genetics & Heredity

African Genetic Diversity: Implications for Human Demographic History, Modern Human Origins, and Complex Disease Mapping

Michael C. Campbell et al.

Annual Review of Genomics and Human Genetics (2008)

Article Genetics & Heredity

Estimation of significance thresholds for genomewide association scans

Frank Dudbridge et al.

GENETIC EPIDEMIOLOGY (2008)

Article Genetics & Heredity

PLINK: A tool set for whole-genome association and population-based linkage analyses

Shaun Purcell et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Genetics & Heredity

Principal components analysis corrects for stratification in genome-wide association studies

Alkes L. Price et al.

NATURE GENETICS (2006)

Review Genetics & Heredity

A comprehensive review of genetic association studies

JN Hirschhorn et al.

GENETICS IN MEDICINE (2002)