4.7 Article

Magneto-Endosomalytic Therapy for Cancer

Journal

ADVANCED HEALTHCARE MATERIALS
Volume 11, Issue 9, Pages -

Publisher

WILEY
DOI: 10.1002/adhm.202101010

Keywords

cancer; endosomalytic; Feraheme; magnetic nanoparticles; therapy; translation

Funding

  1. Department of Bioengineering at the University of Washington

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A simple yet effective cancer treatment method involves repurposing clinically approved magnetic nanoparticles and utilizing static parallel magnetic fields for intracellular nanoparticle self-assembly, leading to targeted cell death while preserving other cells and organs intact. This approach opens up a new avenue for cancer treatment by utilizing nanosciences and nanoparticle design principles accumulated over the past decades.
A remarkably simple yet effective mode of cancer treatment is reported by repurposing clinically approved magnetic nanoparticles (MNPs). Intracellular nanoparticle self-assembly directed by static parallel magnetic fields leads to cell death in targeted tissues while leaving other cells and organs intact. This simple concept opens a new avenue to treat cancer, capitalizing on nanosciences and the nanoparticle (NP) design principles accumulated in the past decades.

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