4.7 Article

Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Role of Oxidative Stress in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Implications for Prevention and Therapy

Johanna C. Arroyave-Ospina et al.

Summary: Oxidative stress plays a major role in the pathophysiology of chronic liver diseases, particularly in non-alcoholic liver disease (NAFLD). The antioxidant response, regulated by the Nrf2/ARE pathway, is crucial in combating oxidative stress-induced damage.

ANTIOXIDANTS (2021)

Review Biochemistry & Molecular Biology

Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis-Roles as Putative Treatment Targets?

Alexandra Zisser et al.

Summary: Hepatic fibrosis is a key predictor of mortality in NASH patients, with activated HSCs playing a crucial role in liver scarring. Targeting the fate of HSCs may hold promise for treating NASH-associated hepatic fibrosis.

BIOMEDICINES (2021)

Review Pharmacology & Pharmacy

Challenges and opportunities in drug development for nonalcoholic steatohepatitis

Matthias Ocker

EUROPEAN JOURNAL OF PHARMACOLOGY (2020)

Editorial Material Gastroenterology & Hepatology

Redefining non-alcoholic fatty liver disease: what's in a name?

[Anonymous]

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

Editorial Material Gastroenterology & Hepatology

From NAFLD to MAFLD: when pathophysiology succeeds

Herbert Tilg et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Article Gastroenterology & Hepatology

Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK

Ana Sandoval-Rodriguez et al.

HEPATOLOGY COMMUNICATIONS (2020)

Article Medicine, General & Internal

Insights Into the Characteristics of Sweet Syndrome in Patients With and Without Hematologic Malignancy

Siting Zheng et al.

FRONTIERS IN MEDICINE (2020)

Article Medicine, Research & Experimental

Pirfenidone prevents and reverses hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages

Guanliang Chen et al.

LABORATORY INVESTIGATION (2019)

Article Cell Biology

Green Tea Prevents NAFLD by Modulation of miR-34a and miR-194 Expression in a High-Fat Diet Mouse Model

L. F. Torres et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

Review Gastroenterology & Hepatology

Human hepatic stellate cell isolation and characterization

Linshan Shang et al.

JOURNAL OF GASTROENTEROLOGY (2018)

Review Gastroenterology & Hepatology

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

Zobair Younossi et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)

Article Biotechnology & Applied Microbiology

Total RNA extraction from tissues for microRNA and target gene expression analysis: not all kits are created equal

Rikki A. M. Brown et al.

BMC BIOTECHNOLOGY (2018)

Review Biochemistry & Molecular Biology

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

David Hojland Ipsen et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Cell Biology

Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease

Mario Masarone et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Review Biochemistry & Molecular Biology

A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease

Zhonge Chen et al.

LIPIDS IN HEALTH AND DISEASE (2017)

Review Gastroenterology & Hepatology

Clinical epidemiology and disease burden of nonalcoholic fatty liver disease

Brandon J. Perumpail et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2017)

Article Multidisciplinary Sciences

Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis

Chikara Komiya et al.

SCIENTIFIC REPORTS (2017)

Article Gastroenterology & Hepatology

Nonalcoholic Fatty Liver Disease in Latinos

Sammy Saab et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2016)

Review Gastroenterology & Hepatology

Role of MicroRNAs in NAFLD/NASH

Gyongyi Szabo et al.

DIGESTIVE DISEASES AND SCIENCES (2016)

Review Biochemistry & Molecular Biology

Molecular Pathogenesis of NASH

Alessandra Caligiuri et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Oncology

miRNAs in non-alcoholic fatty liver disease

Zhen He et al.

FRONTIERS OF MEDICINE (2016)

Article Physiology

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease

Jarkko Soronen et al.

PHYSIOLOGICAL REPORTS (2016)

Review Medicine, General & Internal

Role and New Insights of Pirfenidone in Fibrotic Diseases

David Alejandro Lopez-de la Mora et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2015)

Article Medicine, Research & Experimental

miR-21 regulates triglyceride and cholesterol metabolism in non-alcoholic fatty liver disease by targeting HMGCR

Chuanzheng Sun et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2015)

Review Gastroenterology & Hepatology

miR-122-A key factor and therapeutic target in liver disease

Simonetta Bandiera et al.

JOURNAL OF HEPATOLOGY (2015)

Article Gastroenterology & Hepatology

miRNA-103: Molecular link between insulin resistance and nonalcoholic fatty liver disease

Qian Xu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Article Multidisciplinary Sciences

A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism

Yang Xu et al.

NATURE COMMUNICATIONS (2015)

Article Medicine, General & Internal

Nonalcoholic fatty liver disease

Elizabeth M. Brunt et al.

NATURE REVIEWS DISEASE PRIMERS (2015)

Review Medicine, General & Internal

MicroRNAs in Nonalcoholic Fatty Liver Disease

Gyoergy Baffy

JOURNAL OF CLINICAL MEDICINE (2015)

Review Gastroenterology & Hepatology

MicroRNAs in liver disease

Gyongyi Szabo et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)

Review Gastroenterology & Hepatology

Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis

Seung-Hoi Koo

CLINICAL AND MOLECULAR HEPATOLOGY (2013)

Review Biochemistry & Molecular Biology

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

Anabela P. Rolo et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Article Gastroenterology & Hepatology

Transition from hepatic steatosis to steatohepatitis: Unique microRNA patterns and potential downstream functions and pathways

Xi Jin et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2012)

Review Nutrition & Dietetics

The Role of MicroRNAs in Cholesterol Efflux and Hepatic Lipid Metabolism

Kathryn J. Moore et al.

ANNUAL REVIEW OF NUTRITION, VOL 31 (2011)

Article Multidisciplinary Sciences

MicroRNAs 103 and 107 regulate insulin sensitivity

Mirko Trajkovski et al.

NATURE (2011)

Review Gastroenterology & Hepatology

Obesity and Nonalcoholic Fatty Liver Disease: Biochemical, Metabolic, and Clinical Implications

Elisa Fabbrini et al.

HEPATOLOGY (2010)

Article Pharmacology & Pharmacy

Pirfenidone inhibits carbon tetrachloride- and albumin complex-induced liver fibrosis in rodents by preventing activation of hepatic stellate cells

Xin-Yan Zhao et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2009)

Review Cell Biology

miR-21: a small multi-faceted RNA

Anna M. Krichevsky et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)

Article Biochemical Research Methods

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Da Wei Huang et al.

NATURE PROTOCOLS (2009)

Article Pharmacology & Pharmacy

Potent antioxidant role of Pirfenidone in experimental cirrhosis

Adriana Salazar-Montes et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

Article Gastroenterology & Hepatology

Nonalcoholic Steatohepatitis Is Associated with Altered Hepatic MicroRNA Expression

Onpan Cheung et al.

HEPATOLOGY (2008)

Article Biochemical Research Methods

Analyzing real-time PCR data by the comparative C-T method

Thomas D. Schmittgen et al.

NATURE PROTOCOLS (2008)

Review Biochemistry & Molecular Biology

MicroRNAs: Genomics, biogenesis, mechanism, and function

DP Bartel

Article Gastroenterology & Hepatology

Pirfenidone effectively reverses experimental liver fibrosis

L García et al.

JOURNAL OF HEPATOLOGY (2002)