4.7 Review

Folic Acid Supplementation Improves Glycemic Control for Diabetes Prevention and Management: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Folic acid ameliorates palmitate-induced inflammation through decreasing homocysteine and inhibiting NF-κB pathway in HepG2 cells

Molood Bagherieh et al.

Summary: In this study, it was found that folic acid can attenuate inflammation in HepG2 cells by reducing ROS and homocysteine levels, as well as inhibiting the activation of the NF-kappa B pathway. These findings provide a potential new approach for preventing inflammation in non-alcoholic fatty liver disease.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2023)

Article Biochemistry & Molecular Biology

Effects of concurrent training on irisin and fibronectin type-III domain containing 5 (FNDC5) expression in visceral adipose tissue in type-2 diabetic rats

Ahmad Abdi et al.

Summary: Concurrent training (CT) was found to increase the expression of FNDC5 gene in the visceral adipose tissue (VAT) of type-2 diabetic rats. Additionally, eight weeks of CT improved insulin resistance, insulin, and glucose levels in these rats. However, it did not significantly alter irisin levels.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2022)

Review Food Science & Technology

Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials

Omid Asbaghi et al.

Summary: Folic acid supplementation significantly reduces serum triglyceride and total cholesterol concentrations, but has no effect on LDL and HDL cholesterol concentrations. There is a significant dose-response relationship between the dose of folic acid supplementation and serum concentrations of HDL cholesterol.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Review Nutrition & Dietetics

Effects of pistachios on anthropometric indices, inflammatory markers, endothelial function and blood pressure in adults: a systematic review and meta-analysis of randomised controlled trials

Omid Asbaghi et al.

Summary: The study suggests that consuming pistachios can significantly reduce systolic blood pressure levels but has no significant effects on other indices. Further large-scale studies are needed to confirm these findings.

BRITISH JOURNAL OF NUTRITION (2021)

Review Biochemistry & Molecular Biology

Effects of chromium supplementation on lipid profile in patients with type 2 diabetes: A systematic review and dose-response meta-analysis of randomized controlled trials

Omid Asbaghi et al.

Summary: The study shows that chromium supplementation can significantly improve lipid profile in patients with type 2 diabetes by decreasing TG and TC levels, and increasing HDL levels, but has no significant effect on LDL levels.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2021)

Review Biochemistry & Molecular Biology

Effects of Folic Acid Supplementation on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Omid Asbaghi et al.

Summary: Folic acid supplementation significantly increased serum concentrations of glutathione and total antioxidant capacity, while decreasing serum concentrations of malondialdehyde.

ANTIOXIDANTS (2021)

Review Endocrinology & Metabolism

A Review on Cellular and Molecular Mechanisms Linked to the Development of Diabetes Complications

Rishabh A. Babel et al.

Summary: Modern lifestyle, changing eating habits, and reduced physical work are known to contribute to the global pandemic of diabetes. Hyperglycemia in diabetes leads to both microvascular and macrovascular complications, with oxidative stress and production of reactive oxygen species playing a central role in the development of these complications.

CURRENT DIABETES REVIEWS (2021)

Article Pharmacology & Pharmacy

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

Mengjie Jiang et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Nutrition & Dietetics

Effect of folate supplementation on insulin sensitivity and type 2 diabetes: a meta-analysis of randomized controlled trials

Mads Vendelbo Lind et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2019)

Article Endocrinology & Metabolism

The effect of probiotic supplementation on glycemic control and lipid profile in patients with type 2 diabetes: A randomized placebo controlled trial

Elham Razmpoosh et al.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2019)

Review Endocrinology & Metabolism

The Influence of Psychological Stress on the Initiation and Progression of Diabetes and Cancer

Reza Afrisham et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (2019)

Article Medicine, General & Internal

Predictors of poor glycemic control in adult with type 2 diabetes in South-Eastern Nigeria

Innocent Chidi Anioke et al.

AFRICAN HEALTH SCIENCES (2019)

Article Cell Biology

Folic Acid Improves the Inflammatory Response in LPS-Activated THP-1 Macrophages

Mirian Samblas et al.

MEDIATORS OF INFLAMMATION (2018)

Review Multidisciplinary Sciences

Global folate status in women of reproductive age: a systematic review with emphasis on methodological issues

Lisa M. Rogers et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2018)

Review Endocrinology & Metabolism

Implication of homocysteine in diabetes and impact of folate and vitamin B12 in diabetic population

M. Tahir Mursleen et al.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2017)

Article Endocrinology & Metabolism

The Effects of Folate Supplementation on Carotid Intima-Media Thickness and Metabolic Status in Patients with Metabolic Syndrome

Hamid Reza Talari et al.

ANNALS OF NUTRITION AND METABOLISM (2016)

Article Medicine, Research & Experimental

Investigating the effects of Capparis Spinosa on hepatic gluconeogenesis and lipid content in streptozotocin-induced diabetic rats

Mohammad Taha Jalali et al.

BIOMEDICINE & PHARMACOTHERAPY (2016)

Article Medicine, General & Internal

Evaluation of the effect of high-dose folic acid on endothelial dysfunction in pre-eclamptic patients: A randomized clinical trial

Mohammad Hashemi et al.

JOURNAL OF RESEARCH IN MEDICAL SCIENCES (2016)

Review Medicine, General & Internal

Folic acid and diseases - supplement it or not?

Siaw-Cheok Liew

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA (2016)

Article Nutrition & Dietetics

Folate administration decreases oxidative status and blood pressure in postmenopausal women

Angelo Cagnacci et al.

EUROPEAN JOURNAL OF NUTRITION (2015)

Review Hematology

Measurement of Red Cell Lifespan and Aging

Robert S. Franco

TRANSFUSION MEDICINE AND HEMOTHERAPY (2012)

Article Endocrinology & Metabolism

Effect of folic acid supplementation on biochemical indices in overweight and obese men with type 2 diabetes

Bahram Pourghassem Gargari et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2011)

Review Biochemistry & Molecular Biology

Oxidative stress, insulin signaling, and diabetes

Justin L. Rains et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Article Medicine, General & Internal

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials

Julian P. T. Higgins et al.

BMJ-BRITISH MEDICAL JOURNAL (2011)

Article Medicine, Research & Experimental

Folic Acid and Vitamin B12 Supplementation Improves Coronary Flow Reserve in Elderly Subjects with Vitamin B12 Deficiency

Ramazan Kurt et al.

ARCHIVES OF MEDICAL RESEARCH (2010)

Article Substance Abuse

Gender and alcohol consumption: patterns from the multinational GENACIS project

Richard W. Wilsnack et al.

ADDICTION (2009)

Review Medicine, General & Internal

Gender Differences in Insulin Resistance, Body Composition, and Energy Balance

Eliza B. Geer et al.

GENDER MEDICINE (2009)

Review Medicine, General & Internal

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

David Moher et al.

PLOS MEDICINE (2009)

Article Nutrition & Dietetics

Gender and body size affect the response of erythrocyte folate to folic acid treatment

Renate M. Winkels et al.

JOURNAL OF NUTRITION (2008)

Article Nutrition & Dietetics

Adipose Inflammation, Insulin Resistance, and Cardiovascular Disease

Arti Shah et al.

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2008)

Editorial Material Medicine, General & Internal

GRADE:: an emerging consensus on rating quality of evidence and strength of recommendations

Gordon H. Guyatt et al.

BRITISH MEDICAL JOURNAL (2008)

Article Economics

Gender differences in smoking behavior

Thomas Bauer et al.

HEALTH ECONOMICS (2007)

Article Cardiac & Cardiovascular Systems

Effect of folic acid on endothelial function following acute myocardial infarction

An L. Moens et al.

AMERICAN JOURNAL OF CARDIOLOGY (2007)

Article Medicine, General & Internal

High- but not low-dose folic acid improves endothelial function in coronary artery disease

S. J. Moat et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Endocrinology & Metabolism

Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects

A. Solini et al.

INTERNATIONAL JOURNAL OF OBESITY (2006)

Article Peripheral Vascular Disease

Folic acid improves endothelial dysfunction in type 2 diabetes - an effect independent of homocysteine-lowering

Lawrence M. Title et al.

VASCULAR MEDICINE (2006)

Article Endocrinology & Metabolism

L-folic acid supplementation in healthy postmenopausal women: Effect on homocysteine and glycolipid metabolism

P Villa et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Article Peripheral Vascular Disease

Short-term oral folic acid supplementation enhances endothelial function in patients with type 2 diabetes

AA Mangoni et al.

AMERICAN JOURNAL OF HYPERTENSION (2005)

Article Medicine, General & Internal

Measuring inconsistency in meta-analyses

JPT Higgins et al.

BMJ-BRITISH MEDICAL JOURNAL (2003)

Article Obstetrics & Gynecology

Serum folate and Vitamin B12 levels in women using modern oral contraceptives (OC) containing 20 μg ethinyl estradiol

MW Sütterlin et al.

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2003)

Article Peripheral Vascular Disease

Essential hypertension in adolescents:: Association with insulin resistance and with metabolism of homocysteine and vitamins

R Kahleová et al.

AMERICAN JOURNAL OF HYPERTENSION (2002)

Article Biochemistry & Molecular Biology

Free radical scavenging behavior of folic acid: Evidence for possible antioxidant activity

R Joshi et al.

FREE RADICAL BIOLOGY AND MEDICINE (2001)