Journal
MATERIALS
Volume 14, Issue 16, Pages -Publisher
MDPI
DOI: 10.3390/ma14164543
Keywords
nanoparticles; biosynthesis; antimicrobial activity; Stenocereus queretaroensis peel extract; pitaya peel
Ask authors/readers for more resources
In this study, the phytochemical composition of pitaya peel was evaluated and silver nanoparticles (AgNPs) with potent antimicrobial activity were successfully synthesized using a environmentally friendly biological method. The AgNPs showed strong antimicrobial activity against a variety of bacteria and fungi, suggesting their potential use as disinfectants and in biofilm formulations for packaging products.
The synthesis and application of nanomaterials as antioxidants and cytotoxic agents has increased in recent years. Biological methods go beyond the chemical and physical synthesis that is expensive and not friendly to the environment. Foodborne pathogens and microorganisms causing candidiasis are responsible of 5-10% hospitalized patients. The nutritional properties of the fruit called pitaya, from the Stenocereus queretaroensis species, have been little explored. Therefore, in this study the phytochemical composition of S. queretaroensis peel was evaluated and silver nanoparticles (AgNPs) were synthesized biologically in an environmentally friendly way by S. queretaroensis peel aqueous extract that contains phytochemicals capable of reducing silver nitrate. The antimicrobial activity of the AgNPs was tested by determining the minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC) and time-kill kinetics. AgNPs were characterized visually, by UV-visible spectroscopy and TEM. FTIR spectroscopy identified metabolites responsible for the AgNPs formation. AgNPs showed potent antimicrobial activity against gram-negative and gram-positive bacteria, against fungi, and a methicillin-resistant strain of S. aureus. MIC and MBC values were as low as 0.078 and 0.156 mu g/mL using AgNPs biosynthesized by S. queretaroensis fruit peel and the time kill assay started a log reduction in CFU/mL at 1 x MIC and 2 x MIC. S. queretaroensis-mediated AgNPs could be the basis for the formulation of biofilms for packaging products or as disinfectants for use on different surfaces.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available