Journal
ACS CATALYSIS
Volume 11, Issue 11, Pages 6590-6595Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.1c01670
Keywords
C-H activation; electrochemistry; C-O bond formation; reductive elimination; high-valent pathway
Categories
Funding
- Institute for Basic Science [IBSR010-D1, IBSR010-Y1]
Ask authors/readers for more resources
In this study, a Rh-catalyzed C-H acyloxylation under mild electrolytic conditions was developed, with anodic oxidation of a key rhodacyclic carboxylate intermediate enabling the product-releasing C-O bond-forming reductive elimination process. The accumulation of carboxylate near the electrode surface further induced the desired C-O bond formation, allowing ambient catalytic C-H oxygenation using stoichiometric amounts of readily accessible carboxylic acid coupling partners.
Herein, we describe the development of a Rh-catalyzed C-H acyloxylation under mild electrolytic conditions. Anodic oxidation of a key rhodacyclic carboxylate intermediate was found to enable the product-releasing C-O bond-forming reductive elimination process. An accumulation of carboxylate near the electrode surface was rationalized to further induce the desired C-O bond formation, allowing an ambient catalytic C-H oxygenation using stoichiometric amounts of readily accessible carboxylic acid coupling partners.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available