Related references
Note: Only part of the references are listed.Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria
Ilyas Alav et al.
CHEMICAL REVIEWS (2021)
AcrB: a mean, keen, drug efflux machine
Jessica Kobylka et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2020)
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB
Heng-Keat Tam et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance
Meinan Lyu et al.
MBIO (2020)
Multidrug efflux pumps: structure, function and regulation
Dijun Du et al.
NATURE REVIEWS MICROBIOLOGY (2018)
Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
Martijn Zwama et al.
NATURE COMMUNICATIONS (2018)
Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria
Ganesh Krishnamoorthy et al.
MBIO (2017)
An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump
Zhao Wang et al.
ELIFE (2017)
Polder maps: improving OMIT maps by excluding bulk solvent
Dorothee Liebschner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2017)
Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB
Sabine Schuster et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB
Christine Oswald et al.
NATURE COMMUNICATIONS (2016)
Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate
Abdessamad Ababou et al.
PLOS ONE (2016)
The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
Xian-Zhi Li et al.
CLINICAL MICROBIOLOGY REVIEWS (2015)
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
Thomas Eicher et al.
ELIFE (2014)
Some Ligands Enhance the Efflux of Other Ligands by the Escherichia coli Multidrug Pump AcrB
Alfred D. Kinana et al.
BIOCHEMISTRY (2013)
RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms
Paolo Ruggerone et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Structural basis for the inhibition of bacterial multidrug exporters
Ryosuke Nakashima et al.
NATURE (2013)
Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution
Jeffrey J. Headd et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
Thomas Eicher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
Eva Chovancova et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
REFMAC5 for the refinement of macromolecular crystal structures
Garib N. Murshudov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Overview of the CCP4 suite and current developments
Martyn D. Winn et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
Ryosuke Nakashima et al.
NATURE (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
XDS
Wolfgang Kabsch
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Substrate path in the AcrB multidrug efflux pump of Escherichia coli
Fasahath Husain et al.
MOLECULAR MICROBIOLOGY (2010)
Crucial Role of Asp408 in the Proton Translocation Pathway of Multidrug Transporter AcrB: Evidence from Site-Directed Mutagenesis and Carbodiimide Labeling
Markus A. Seeger et al.
BIOCHEMISTRY (2009)
Mechanisms of RND multidrug efflux pumps
Hiroshi Nikaido et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2009)
Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli
Keiji Nagano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance
Markus A. Seeger et al.
CURRENT DRUG TARGETS (2008)
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB
Markus A. Seeger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Microscale fluorescent thermal stability assay for membrane proteins
Alexander I. Alexandrov et al.
STRUCTURE (2008)
Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors
Gaby Sennhauser et al.
PLOS BIOLOGY (2007)
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Satoshi Murakami et al.
NATURE (2006)
Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism
Markus A. Seeger et al.
SCIENCE (2006)
Crystal structure of bacterial multidrug efflux transporter AcrB
S Murakami et al.
NATURE (2002)
Purification, crystallization and preliminary diffraction studies of AcrB, an inner-membrane multi-drug efflux protein
KM Pos et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2002)