4.8 Article

Community factors and excess mortality in first wave of the COVID-19 pandemic in England

Journal

NATURE COMMUNICATIONS
Volume 12, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41467-021-23935-x

Keywords

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Funding

  1. PHE as part of the MRC-PHE Centre for Environment and Health
  2. UK Medical Research Council [MR/L01341X/1]
  3. National Institute for Health Research (NIHR) through its Health Protection Units (HPRUs) at Imperial College London in Environmental Exposures and Health and in Chemical and Radiation Threats and Hazards
  4. National Institute for Health Research (NIHR) through Health Data Research UK (HDR UK)
  5. Medical Research Council (MRC) [MR/S019669/1]
  6. British Heart Foundation Imperial College Centre for Research Excellence [RE/18/4/34215]
  7. NIHR Imperial College Biomedical Research Centre (BRC)
  8. NIHR HPRU in Environmental Exposures and Health [NIHR-200880]
  9. NIHR HPRU in Chemical and Radiation Threats and Hazards [NIHR-200922]
  10. HDR UK
  11. UK Dementia Research Institute at Imperial College London
  12. UK Medical Research Council
  13. Alzheimer's Research UK [MC_PC_17114]
  14. Huo Family Foundation for research into COVID-19
  15. Wellcome Trust [209376/Z/17/Z]
  16. US Environmental Protection Agency (EPA), as part of the Centre for Clean Air Climate Solution [R835873]
  17. HDR UK Hub DISCOVER-NOW
  18. Alzheimer's Society

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This study identified characteristics at the community level associated with increased risk of excess mortality during the first wave of the COVID-19 pandemic in England, including high density of care homes, high proportion of residents on income support, living in overcrowded homes, and non-white ethnicity. No association was found with population density or air pollution.
Risk factors for increased risk of death from COVID-19 have been identified, but less is known on characteristics that make communities resilient or vulnerable to the mortality impacts of the pandemic. We applied a two-stage Bayesian spatial model to quantify inequalities in excess mortality in people aged 40 years and older at the community level during the first wave of the pandemic in England, March-May 2020 compared with 2015-2019. Here we show that communities with an increased risk of excess mortality had a high density of care homes, and/or high proportion of residents on income support, living in overcrowded homes and/or with a non-white ethnicity. We found no association between population density or air pollution and excess mortality. Effective and timely public health and healthcare measures that target the communities at greatest risk are urgently needed to avoid further widening of inequalities in mortality patterns as the pandemic progresses. COVID-19-related mortality in England shows geographical variation but the reasons for this are not well understood. This study estimated excess mortality in the first wave of the pandemic and found associations with higher density of care homes, overcrowding, and economic deprivation, but not with population density or air pollution.

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