Related references
Note: Only part of the references are listed.Mapping the SARS-CoV-2-Host Protein-Protein Interactome by Affinity Purification Mass Spectrometry and Proximity-Dependent Biotin Labeling: A Rational and Straightforward Route to Discover Host-Directed Anti-SARS-CoV-2 Therapeutics
Rosa Terracciano et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir
Goran Kokic et al.
NATURE COMMUNICATIONS (2021)
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
Kirill Gorshkov et al.
ACS INFECTIOUS DISEASES (2021)
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
Alexey Stukalov et al.
NATURE (2021)
Regulation of LC3B levels by ubiquitination and proteasomal degradation
Rui Jia et al.
AUTOPHAGY (2020)
Disposing of misfolded ER proteins: A troubled substrate's way out of the ER
Christina Oikonomou et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou et al.
NATURE (2020)
A Novel Coronavirus from Patients with Pneumonia in China, 2019
Na Zhu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
ER-Phagy: Quality Control and Turnover of Endoplasmic Reticulum
Haruka Chino et al.
TRENDS IN CELL BIOLOGY (2020)
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
Timothy P. Sheahan et al.
NATURE COMMUNICATIONS (2020)
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya et al.
NATURE MICROBIOLOGY (2020)
COVID-19: consider cytokine storm syndromes and immunosuppression
Puja Mehta et al.
LANCET (2020)
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
Denisa Bojkova et al.
NATURE (2020)
The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Mehdi Bouhaddou et al.
CELL (2020)
Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets
Katia Fecchi et al.
FRONTIERS IN MICROBIOLOGY (2020)
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
Natacha S. Ogando et al.
JOURNAL OF GENERAL VIROLOGY (2020)
Coronavirus interactions with the cellular autophagy machinery
Katelyn Miller et al.
AUTOPHAGY (2020)
A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis
Eric J. Snijder et al.
PLOS BIOLOGY (2020)
Shotgun proteomics analysis of SARS-CoV-2-infected cells and how it can optimize whole viral particle antigen production for vaccines
Lucia Grenga et al.
EMERGING MICROBES & INFECTIONS (2020)
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis
Yaping Wei et al.
PHARMACOLOGICAL RESEARCH (2019)
Human Coronavirus: Host-Pathogen Interaction
To Sing Fung et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 73 (2019)
The N-Degron Pathway Mediates ER-phagy
Chang Hoon Ji et al.
MOLECULAR CELL (2019)
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
Yingyao Zhou et al.
NATURE COMMUNICATIONS (2019)
A Phase II, Multicenter, Single-Arm Study of Mipsagargin (G-202) as a Second-Line Therapy Following Sorafenib for Adult Patients with Progressive Advanced Hepatocellular Carcinoma
Devalingam Mahalingam et al.
CANCERS (2019)
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
Ariane J. Brown et al.
ANTIVIRAL RESEARCH (2019)
UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
Megan C. Kopp et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends
Kristine Faye R. Pobre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Cellular Zinc Finger Protein 622 Hinders Human Adenovirus Lytic Growth and Limits Binding of the Viral pVII Protein to Virus DNA
Kwangchol Mun et al.
JOURNAL OF VIROLOGY (2019)
Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation
Dara E. Leto et al.
MOLECULAR CELL (2019)
The PRIDE database and related tools and resources in 2019: improving support for quantification data
Yasset Perez-Riverol et al.
NUCLEIC ACIDS RESEARCH (2019)
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
Damian Szklarczyk et al.
NUCLEIC ACIDS RESEARCH (2019)
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
G. Elif Karagoz et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)
fastp: an ultra-fast all-in-one FASTQ preprocessor
Shifu Chen et al.
BIOINFORMATICS (2018)
Divergent synthesis of thapsigargin analogs
Hang Chu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α
Denisse Sepulveda et al.
MOLECULAR CELL (2018)
The Unfolded Protein Response and Cell Fate Control
Claudio Hetz et al.
MOLECULAR CELL (2018)
A brief history of autophagy from cell biology to physiology and disease
Noboru Mizushima
NATURE CELL BIOLOGY (2018)
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
Tsun-Kai Chang et al.
MOLECULAR CELL (2018)
Use of a temporary immersion bioreactor system for the sustainable production of thapsigargin in shoot cultures of Thapsia garganica
Carmen Quinonero Lopez et al.
PLANT METHODS (2018)
Scalable Synthesis of (-)-Thapsigargin
Hang Chu et al.
ACS CENTRAL SCIENCE (2017)
HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum
Jie Wang et al.
GENE (2017)
Monitoring and Measuring Autophagy
Saori R. Yoshii et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response
Pankaj Sehgal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Activation of the Unfolded Protein Response by Lipid Bilayer Stress
Kristina Halbleib et al.
MOLECULAR CELL (2017)
Fine-tuning PERK signaling to control cell fate under stress
Hery Urra et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Pathview Web: user friendly pathway visualization and data integration
Weijun Luo et al.
NUCLEIC ACIDS RESEARCH (2017)
The Growing Toolbox for Protein Synthesis Studies
Shintaro Iwasaki et al.
TRENDS IN BIOCHEMICAL SCIENCES (2017)
Fine-tuning PERK signaling to control cell fate under stress
Hery Urra et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells
Michael Poppe et al.
PLOS PATHOGENS (2017)
Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours
D. Mahalingam et al.
BRITISH JOURNAL OF CANCER (2016)
Protein misfolding in the endoplasmic reticulum as a conduit to human disease
Miao Wang et al.
NATURE (2016)
The Perseus computational platform for comprehensive analysis of (prote)omics data
Stefka Tyanova et al.
NATURE METHODS (2016)
The MaxQuant computational platform for mass spectrometry-based shotgun proteomics
Stefka Tyanova et al.
NATURE PROTOCOLS (2016)
SARS and MERS: recent insights into emerging coronaviruses
Emmie de Wit et al.
NATURE REVIEWS MICROBIOLOGY (2016)
Coronaviruses and the human airway: a universal system for virus-host interaction studies
Hulda R. Jonsdottir et al.
VIROLOGY JOURNAL (2016)
Endoplasmic Reticulum: The Favorite Intracellular Niche for Viral Replication and Assembly
Ines Romero-Brey et al.
VIRUSES-BASEL (2016)
The unfolded protein response in immunity and inflammation
Joep Grootjans et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling
Marta Carrara et al.
EMBO JOURNAL (2015)
p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
Yoshinori Katsuragi et al.
FEBS JOURNAL (2015)
Role of the Unfolded Protein Response, GRP78 and GRP94 in Organ Homeostasis
Genyuan Zhu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2015)
BiP and Its Nucleotide Exchange Factors Grp170 and Sil1: Mechanisms of Action and Biological Functions
Julia Behnke et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
Thapsigargin-From Thapsia L. to Mipsagargin
Trine Bundgaard Andersen et al.
MOLECULES (2015)
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation
Shengyi Sun et al.
NATURE CELL BIOLOGY (2015)
Targeting thapsigargin towards tumors
Nhu Thi Quynh Doan et al.
STEROIDS (2015)
Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification
Caroline Mauvezin et al.
NATURE COMMUNICATIONS (2015)
The cystathionine γ-lyase/hydrogen sulfide system maintains cellular glutathione status
Zheng-Wei Lee et al.
BIOCHEMICAL JOURNAL (2014)
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Yang Liao et al.
BIOINFORMATICS (2014)
Endoplasmic reticulum stress response in yeast and humans
Haoxi Wu et al.
BIOSCIENCE REPORTS (2014)
How Viruses Hijack the ERAD Tuning Machinery
Julia Noack et al.
JOURNAL OF VIROLOGY (2014)
Herp coordinates compartmentalization and recruitment of HRD1 and misfolded proteins for ERAD
Julia Leitman et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
ERAD and how viruses exploit it
Hyewon Byun et al.
FRONTIERS IN MICROBIOLOGY (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Herp depletion protects from protein aggregation by up-regulating autophagy
Clara Quiroga et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
Jaeseok Han et al.
NATURE CELL BIOLOGY (2013)
IRE1: ER stress sensor and cell fate executor
Yani Chen et al.
TRENDS IN CELL BIOLOGY (2013)
Coronavirus infections in hospitalized pediatric patients with acute respiratory tract disease
Monika Jevsnik et al.
BMC INFECTIOUS DISEASES (2012)
Cleaning Up: ER-Associated Degradation to the Rescue
Jeffrey L. Brodsky
CELL (2012)
Endoplasmic reticulum stress regulation of the Kar2p/BiP chaperone alleviates proteotoxicity via dual degradation pathways
Chia-Ling Hsu et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Defining human ERAD networks through an integrative mapping strategy
John C. Christianson et al.
NATURE CELL BIOLOGY (2012)
Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
The structure of the PERK kinase domain suggests the mechanism for its activation
Wenjun Cui et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2011)
Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy
Ian G. Ganley et al.
AUTOPHAGY (2011)
Update on Rhinovirus and Coronavirus Infections
Stephen B. Greenberg
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus
Ying Liao et al.
VIROLOGY (2011)
CHAC1/MGC4504 Is a Novel Proapoptotic Component of the Unfolded Protein Response, Downstream of the ATF4-ATF3-CHOP Cascade
Imran N. Mungrue et al.
JOURNAL OF IMMUNOLOGY (2009)
Characterization of an ERAD pathway for nonglyclosylated BiP substrates, which require Herp
Yuki Okuda-Shimizu et al.
MOLECULAR CELL (2007)
Advances in immunosuppressive therapy
Wendy Marder et al.
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2007)
Integration of biological networks and gene expression data using Cytoscape
Melissa S. Cline et al.
NATURE PROTOCOLS (2007)
Genetic variability of human coronavirus OC43-, 229E-, and NL63-like strains and their association with lower respiratory tract infections of hospitalized infants and immunocompromised patients
G Gerna et al.
JOURNAL OF MEDICAL VIROLOGY (2006)
JNK and PI3k/Akt signaling pathways are required for establishing persistent SARS-CoV infection in Vero E6 cells
T Mizutani et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
Inhibition of beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3
M Spiegel et al.
JOURNAL OF VIROLOGY (2005)
Herp is dually regulated by both the endoplasmic reticulum stress-specific branch of the unfolded protein response and a branch that is shared with other cellular stress pathways
YJ Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome
Y Guan et al.
LANCET (2004)
Characterization of a novel coronavirus associated with severe acute respiratory syndrome
PA Rota et al.
SCIENCE (2003)
Identification of a novel coronavirus in patients with severe acute respiratory syndrome
C Drosten et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress
K Kokame et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution
C Toyoshima et al.
NATURE (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)