4.8 Article

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

Related references

Note: Only part of the references are listed.
Editorial Material Chemistry, Medicinal

Spotlight on AKT: Current Therapeutic Challenges

Ina Landel et al.

ACS MEDICINAL CHEMISTRY LETTERS (2020)

Article Biochemistry & Molecular Biology

The EMBL-EBI search and sequence analysis tools APIs in 2019

Fabio Madeira et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Chemistry, Multidisciplinary

Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity

Lena Quambusch et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Biochemistry & Molecular Biology

SWISS-MODEL: homology modelling of protein structures and complexes

Andrew Waterhouse et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Oncology

AKT Inhibition in Solid Tumors With AKT1 Mutations

David M. Hyman et al.

JOURNAL OF CLINICAL ONCOLOGY (2017)

Article Biochemistry & Molecular Biology

Covalent Protein Labeling at Glutamic Acids

Pablo Martin-Gago et al.

CELL CHEMICAL BIOLOGY (2017)

Article Chemistry, Multidisciplinary

Covalent-Allosteric Kinase Inhibitors

Joern Weisner et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Multidisciplinary Sciences

Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression

Nicolle M. Linnerth-Petrik et al.

PLOS ONE (2014)

Article Multidisciplinary Sciences

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

Phillip A. Schwartz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Chemistry, Multidisciplinary

The PDB_REDO server for macromolecular structure model optimization

Robbie P. Joosten et al.

IUCRJ (2014)

Article Biochemical Research Methods

Towards automated crystallographic structure refinement with phenix.refine

Pavel V. Afonine et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)

Review Cell Biology

Akt signalling in health and disease

Ingeborg Hers et al.

CELLULAR SIGNALLING (2011)

Article Biochemical Research Methods

MolProbity: all-atom structure validation for macromolecular crystallography

Vincent B. Chen et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Biochemical Research Methods

XDS

Wolfgang Kabsch

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Cell Biology

The Akt isoforms are present at distinct subcellular locations

Stacey A. Santi et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)

Review Chemistry, Medicinal

Proteus in the World of Proteins: Conformational Changes in Protein Kinases

Matthias Rabiller et al.

ARCHIV DER PHARMAZIE (2010)

Article Cell Biology

The Akt kinases Isoform specificity in metabolism and cancer

Eva Gonzalez et al.

CELL CYCLE (2009)

Review Biochemistry & Molecular Biology

PI3K/Akt: getting it right matters

T. F. Franke

ONCOGENE (2008)

Article Biochemistry & Molecular Biology

Novel inositol phospholipid headgroup surrogate crystallized in the pleckstrin homology domain of protein kinase Bα

Stephen J. Mills et al.

ACS CHEMICAL BIOLOGY (2007)

Review Oncology

Ba/F3 cells and their use in kinase drug discovery

Markus Warmuth et al.

CURRENT OPINION IN ONCOLOGY (2007)

Review Biochemistry & Molecular Biology

Perturbations of the AKT signaling pathway in human cancer

DA Altomare et al.

ONCOGENE (2005)

Article Biochemical Research Methods

PRODRG:: a tool for high-throughput crystallography of protein-ligand complexes

AW Schüttelkopf et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Multidisciplinary Sciences

Exploring biology with small organic molecules

BR Stockwell

NATURE (2004)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Crystal structure of an inactive Akt2 kinase domain

X Huang et al.

STRUCTURE (2003)