4.7 Review

Fusion genes in gynecologic tumors: the occurrence, molecular mechanism and prospect for therapy

Related references

Note: Only part of the references are listed.
Article Oncology

Cancer statistics, 2020

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2020)

Article Multidisciplinary Sciences

Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary

Sarah H. Kim et al.

NATURE COMMUNICATIONS (2020)

Article Oncology

Inhibition of MAN2A1 Enhances the Immune Response to Anti-PD-L1 in Human Tumors

Sailing Shi et al.

CLINICAL CANCER RESEARCH (2020)

Article Multidisciplinary Sciences

Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer

Elizabeth L. Christie et al.

NATURE COMMUNICATIONS (2019)

Article Pathology

Clinicopathologic Characterization of GREB1-rearranged Uterine Sarcomas With Variable Sex-Cord Differentiation

Cheng-Han Lee et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2019)

Article Biochemistry & Molecular Biology

Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer

Zannel Blanchard et al.

GENOME RESEARCH (2019)

Review Genetics & Heredity

BCOR involvement in cancer

Annalisa Astolfi et al.

EPIGENOMICS (2019)

Review Oncology

The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis

Stephen P. Ducray et al.

CANCERS (2019)

Article Biotechnology & Applied Microbiology

JAZF1 Suppresses Papillary Thyroid Carcinoma Cell Proliferation and Facilitates Apoptosis via Regulating TAK1/NF-κB Pathways

Liangliang Huang et al.

ONCOTARGETS AND THERAPY (2019)

Review Oncology

Targeting chromatin complexes in fusion protein-driven malignancies

Gerard L. Brien et al.

NATURE REVIEWS CANCER (2019)

Article Cell Biology

FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signalling

Ting Cai et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)

Article Medicine, Research & Experimental

Hedgehog signaling drives medulloblastoma growth via CDK6

David R. Raleigh et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Oncology

Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer

Alexey A. Efanov et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Article Biochemistry & Molecular Biology

TumorFusions: an integrative resource for cancer-associated transcript fusions

Xin Hu et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Oncology

Jazf1 promotes prostate cancer progression by activating JNK/Slug

Yonghun Sung et al.

ONCOTARGET (2018)

Article Oncology

Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer

Alexey A. Efanov et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Article Pathology

ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus

Nissreen Mohammad et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2018)

Article Oncology

Identification of novel cyclin gene fusion transcripts in endometrioid ovarian carcinomas

Antonio Agostini et al.

INTERNATIONAL JOURNAL OF CANCER (2018)

Article Biochemistry & Molecular Biology

FHL2 interacts with EGFR to promote glioblastoma growth

Lili Sun et al.

ONCOGENE (2018)

Article Oncology

Novel EPC1 gene fusions in endometrial stromal sarcoma

Brendan C. Dickson et al.

GENES CHROMOSOMES & CANCER (2018)

Article Multidisciplinary Sciences

A metabolic function of FGFR3-TACC3 gene fusions in cancer

Veronique Frattini et al.

NATURE (2018)

Article Gastroenterology & Hepatology

MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice

Zhang-Hui Chen et al.

GASTROENTEROLOGY (2017)

Article Oncology

Fusion of the genes BRD8 and PHF1 in endometrial stromal sarcoma

Francesca Micci et al.

GENES CHROMOSOMES & CANCER (2017)

Review Medicine, General & Internal

Uterine inflammatory myofibroblastic tumor: more common than expected Case report and review

Vincenzo Dario Mandato et al.

MEDICINE (2017)

Article Multidisciplinary Sciences

Polycomb-like proteins link the PRC2 complex to CpG islands

Haojie Li et al.

NATURE (2017)

Article Multidisciplinary Sciences

Chronic sun exposure-related fusion oncogenes EGFR-PPARGC1A in cutaneous squamous cell carcinoma

Sho Egashira et al.

SCIENTIFIC REPORTS (2017)

Article Oncology

Involvement of DPP9 in gene fusions in serous ovarian carcinoma

Marianne Lislerud Smebye et al.

BMC CANCER (2017)

Article Pathology

Uterine Inflammatory Myofibroblastic Tumors Frequently Harbor ALK Fusions With IGFBP5 and THBS1

Josh D. Haimes et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2017)

Article Biochemistry & Molecular Biology

INTEGRATE: gene fusion discovery using whole genome and transcriptome data

Jin Zhang et al.

GENOME RESEARCH (2016)

Review Genetics & Heredity

JAZF1/SUZ12 gene fusion in endometrial stromal sarcomas

Andelko Hrzenjak

ORPHANET JOURNAL OF RARE DISEASES (2016)

Article Medicine, Research & Experimental

Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer

Anne Laugesen et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

Review Pharmacology & Pharmacy

An overview of microRNAs

Scott M. Hammond

ADVANCED DRUG DELIVERY REVIEWS (2015)

Review Cell Biology

Detecting and targetting oncogenic fusion proteins in the genomic era

Monika A. Davare et al.

BIOLOGY OF THE CELL (2015)

Letter Gastroenterology & Hepatology

GLI2 as a Marker of Hedgehog-Responsive Cells

Alexandra Grzelak Candice et al.

HEPATOLOGY (2015)

Editorial Material Oncology

The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene

Michael M. Gottesman et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Article Multidisciplinary Sciences

Recurrent BCAM-AKT2 fusion gene leads to a constitutively activated AKT2 fusion kinase in high-grade serous ovarian carcinoma

Kalpana Kannan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Novel kinase fusion transcripts found in endometrial cancer

Ryo Tamura et al.

SCIENTIFIC REPORTS (2015)

Editorial Material Oncology

The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene

Michael M. Gottesman et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Review Oncology

The emerging complexity of gene fusions in cancer

Fredrik Mertens et al.

NATURE REVIEWS CANCER (2015)

Article Biochemical Research Methods

circlize implements and enhances circular visualization in R

Zuguang Gu et al.

BIOINFORMATICS (2014)

Review Obstetrics & Gynecology

Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature

Erin A. Blake et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2014)

Review Oncology

Chimeric RNAs Generated by Intergenic Splicing in Normal and Cancer Cells

Kasey Jividen et al.

GENES CHROMOSOMES & CANCER (2014)

Article Oncology

Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma

Barbara Dewaele et al.

INTERNATIONAL JOURNAL OF CANCER (2014)

Article Oncology

RET Rearrangements in Lung Adenocarcinoma and Radiation

Sanja Dacic et al.

JOURNAL OF THORACIC ONCOLOGY (2014)

Article Multidisciplinary Sciences

Integrated genomic characterization of endometrial carcinoma

Gad Getz et al.

NATURE (2013)

Article Genetics & Heredity

Activating ESR1 mutations in hormone-resistant metastatic breast cancer

Dan R. Robinson et al.

NATURE GENETICS (2013)

Review Oncology

Tyrosine kinase gene rearrangements in epithelial malignancies

Alice T. Shaw et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

Rsk-mediated phosphorylation and 14-3-3ε binding of Apaf-1 suppresses cytochrome c-induced apoptosis

Jiyeon Kim et al.

EMBO JOURNAL (2012)

Article Multidisciplinary Sciences

Novel Fusion of MYST/Esa1-Associated Factor 6 and PHF1 in Endometrial Stromal Sarcoma

Ioannis Panagopoulos et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma

Cheng-Han Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

Philip J. Stephens et al.

Article Biochemistry & Molecular Biology

Isoform-specific Regulation of Akt Signaling by the Endosomal Protein WDFY2

Helena A. Walz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Multidisciplinary Sciences

A small-cell lung cancer genome with complex signatures of tobacco exposure

Erin D. Pleasance et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

Inhibition of proliferation and differentiation and promotion of apoptosis by cyclin L2 in mouse embryonic carcinoma P19 cells

Lili Zhuo et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Review Cell Biology

Biochemical mechanisms of gene regulation by polycomb group protein complexes

Juerg Mueller et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)

Article Multidisciplinary Sciences

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

Ram-Shankar Mani et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore

Kim De Keersmaecker et al.

MOLECULAR CELL (2008)

Review Oncology

MLL translocations, histone modifications and leukaemia stem-cell development

Andrei V. Krivtsov et al.

NATURE REVIEWS CANCER (2007)

Article Medicine, General & Internal

Overexpression of cyclin L2 induces apoptosis and cell-cycle arrest in human lung cancer cells

Li Hong-li et al.

CHINESE MEDICAL JOURNAL (2007)

Review Oncology

The impact of translocations and gene fusions on cancer causation

Felix Mitelman et al.

NATURE REVIEWS CANCER (2007)

Review Biochemistry & Molecular Biology

Evidence of recurrent gene fusions in common epithelial tumors

Chandan Kumar-Sinha et al.

TRENDS IN MOLECULAR MEDICINE (2006)

Review Oncology

Rare uterine cancers

S Acharya et al.

LANCET ONCOLOGY (2005)

Article Multidisciplinary Sciences

Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

Y Hahn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4

T Nakajima et al.

NUCLEIC ACIDS RESEARCH (2004)

Review Cell Biology

Closing in on the biological functions of FPS/FES and FER

P Greer

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Oncology

Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family

E de Alava et al.

JOURNAL OF CLINICAL ONCOLOGY (2000)