4.5 Article

The Nuclear Lamina

Related references

Note: Only part of the references are listed.
Article Cell & Tissue Engineering

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

Parisha P. Shah et al.

Summary: Pathogenic mutations in LMNA can lead to abnormal nuclear structure and laminopathies, with specific disruptions in peripheral chromatin and gene misexpression in non-myocyte lineages, highlighting the role of lamina-chromatin interactions in safeguarding cellular identity.

CELL STEM CELL (2021)

Review Cell Biology

LINC complex regulation of genome organization and function

Xianrong Wong et al.

Summary: Disruption to nuclear organization and architecture can contribute to various diseases. The LINC complexes, which connect the nucleus to cytoplasmic cytoskeletal networks, play a crucial role in the physical organization and function of the genome. This connection allows for the constant detection of environmental mechanical stimuli, resulting in altered regulation of nuclear architecture and genome function.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2021)

Article Biology

Mapping the micro-proteome of the nuclear lamina and lamina-associated domains

Xianrong Wong et al.

Summary: The nuclear lamina is a protein network that provides structural and gene regulatory functions. LADs are a large fraction of the mammalian genome that are repressed by their association to the nuclear periphery. By using two different methods, proteins at the nuclear periphery have been identified and essential proteins for LAD function have been discovered.

LIFE SCIENCE ALLIANCE (2021)

Review Genetics & Heredity

Methods for mapping 3D chromosome architecture

Rieke Kempfer et al.

NATURE REVIEWS GENETICS (2020)

Review Genetics & Heredity

Advances in Chromatin Imaging at Kilobase-Scale Resolution

Alistair Boettiger et al.

TRENDS IN GENETICS (2020)

Review Genetics & Heredity

The Laminopathies and the Insights They Provide into the Structural and Functional Organization of the Nucleus

Xianrong Wong et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 21, 2020 (2020)

Article Multidisciplinary Sciences

Histone H3K9 methylation promotes formation of genome compartments in Caenorhabditis elegans via chromosome compaction and perinuclear anchoring

Qian Bian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Cell Biology

Fluid-like chromatin: Toward understanding the real chromatin organization present in the cell

Kazuhiro Maeshima et al.

CURRENT OPINION IN CELL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Cell cycle dynamics of lamina-associated DNA

Tom van Schaik et al.

EMBO REPORTS (2020)

Article Biochemistry & Molecular Biology

Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells

Hilmar Strickfaden et al.

Review Biochemistry & Molecular Biology

Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq

Shaoqian Ma et al.

MOLECULAR BIOMEDICINE (2020)

Review Biotechnology & Applied Microbiology

Lamina-associated domains: peripheral matters and internal affairs

Nolwenn Briand et al.

GENOME BIOLOGY (2020)

Article Engineering, Biomedical

The Driving Force: Nuclear Mechanotransduction in Cellular Function, Fate, and Disease

Melanie Maurer et al.

Annual Review of Biomedical Engineering (2019)

Article Biochemistry & Molecular Biology

Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs

Christ Leemans et al.

Article Multidisciplinary Sciences

Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei

Daphne S. Cabianca et al.

NATURE (2019)

Article Multidisciplinary Sciences

Heterochromatin drives compartmentalization of inverted and conventional nuclei

Martin Falk et al.

NATURE (2019)

Article Multidisciplinary Sciences

Chromatin structure dynamics during the mitosis-to-G1 phase transition

Haoyue Zhang et al.

NATURE (2019)

Review Genetics & Heredity

Coaching from the sidelines: the nuclear periphery in genome regulation

Abigail Buchwalter et al.

NATURE REVIEWS GENETICS (2019)

Article Cell Biology

Mechanotransduction via the LINC complex regulates DNA replication in myonuclei

Shuoshuo Wang et al.

JOURNAL OF CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Lamins Organize the Global Three-Dimensional Genome from the Nuclear Periphery

Xiaobin Zheng et al.

MOLECULAR CELL (2018)

Article Multidisciplinary Sciences

A pathway for mitotic chromosome formation

Johan H. Gibcus et al.

SCIENCE (2018)

Article Chemistry, Multidisciplinary

A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks

Bingbing X. Li et al.

ACS CENTRAL SCIENCE (2018)

Article Cell Biology

The Emerging Role of Lamin C as an Important LMNA Isoform in Mechanophenotype

Rafael D. Gonzalez-Cruz et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)

Article Multidisciplinary Sciences

Phase separation drives heterochromatin domain formation

Amy R. Strom et al.

NATURE (2017)

Article Multidisciplinary Sciences

The molecular architecture of lamins in somatic cells

Yagmur Turgay et al.

NATURE (2017)

Article Multidisciplinary Sciences

Two independent modes of chromatin organization revealed by cohesin removal

Wibke Schwarzer et al.

NATURE (2017)

Article Multidisciplinary Sciences

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

Adam G. Larson et al.

NATURE (2017)

Article Cell Biology

Identification of novel RNA isoforms of LMNA

Emily DeBoy et al.

NUCLEUS (2017)

Article Cell Biology

Identification of novel RNA isoforms of LMNA

Emily DeBoy et al.

NUCLEUS (2017)

Article Biochemistry & Molecular Biology

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction

Andrey Poleshko et al.

Article Biochemistry & Molecular Biology

A-type Lamins Form Distinct Filamentous Networks with Differential Nuclear Pore Complex Associations

Wei Xie et al.

CURRENT BIOLOGY (2016)

Review Biochemistry & Molecular Biology

Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man

Jennifer C. Harr et al.

EMBO REPORTS (2016)

Article Chemistry, Physical

Transcription upregulation via force-induced direct stretching of chromatin

Arash Tajik et al.

NATURE MATERIALS (2016)

Article Cell Biology

Laminopathies disrupt epigenomic developmental programs and cell fate

Jelena Perovanovic et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Review Biochemistry & Molecular Biology

Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation

Yosef Gruenbaum et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)

Review Biochemistry & Molecular Biology

Making the LINC: SUN and KASH protein interactions

Dae In Kim et al.

BIOLOGICAL CHEMISTRY (2015)

Article Engineering, Biomedical

Cytoskeletal tension induces the polarized architecture of the nucleus

Dong-Hwee Kim et al.

BIOMATERIALS (2015)

Article Biochemistry & Molecular Biology

Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

Jop Kind et al.

Article Biochemistry & Molecular Biology

53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair

Francisca Lottersberger et al.

Article Biochemistry & Molecular Biology

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos

Adriana Gonzalez-Sandoval et al.

Review Cell Biology

Nuclear membrane diversity: underlying tissue-specific pathologies in disease?

Howard J. Worman et al.

CURRENT OPINION IN CELL BIOLOGY (2015)

Review Cell Biology

Lamins: the structure and protein complexes

Yosef Gruenbaum et al.

CURRENT OPINION IN CELL BIOLOGY (2015)

Review Cell Biology

Lamins at the crossroads of mechanosignaling

Selma Osmanagic-Myers et al.

GENES & DEVELOPMENT (2015)

Review Cell Biology

Accessorizing and anchoring the LINC complex for multifunctionality

Wakam Chang et al.

JOURNAL OF CELL BIOLOGY (2015)

Article Cell Biology

Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy

Takeshi Shimi et al.

MOLECULAR BIOLOGY OF THE CELL (2015)

Article Biochemistry & Molecular Biology

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changesin cellular differentiation

James Fraser et al.

MOLECULAR SYSTEMS BIOLOGY (2015)

Article Multidisciplinary Sciences

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

Adrian L. Sanborn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness

Takashi Furusawa et al.

NATURE COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

The p.R482W substitution in A-type lamins deregulates SREBP1 activity in Dunnigan-type familial partial lipodystrophy

Nathalie Vadrot et al.

HUMAN MOLECULAR GENETICS (2015)

Review Biotechnology & Applied Microbiology

Chromatin states and nuclear organization in development - a view from the nuclear lamina

Anna Mattout et al.

GENOME BIOLOGY (2015)

Article Biophysics

Actomyosin Pulls to Advance the Nucleus in a Migrating Tissue Cell

Jun Wu et al.

BIOPHYSICAL JOURNAL (2014)

Article Biochemistry & Molecular Biology

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Suhas S. P. Rao et al.

Article Cell Biology

NET gains and losses: the role of changing nuclear envelope proteomes in genome regulation

Xianrong Wong et al.

CURRENT OPINION IN CELL BIOLOGY (2014)

Article Cell Biology

Nucleolus and nuclear periphery: Velcro for heterochromatin

Jan Padeken et al.

CURRENT OPINION IN CELL BIOLOGY (2014)

Article Cell Biology

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

Takamasa Harada et al.

JOURNAL OF CELL BIOLOGY (2014)

Article Cell Biology

Interphase phosphorylation of lamin A

Vitaly Kochin et al.

JOURNAL OF CELL SCIENCE (2014)

Article Biochemistry & Molecular Biology

Nuclear Structures Surrounding Internal Lamin Invaginations

Sona Legartova et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2014)

Article Multidisciplinary Sciences

Topologically associating domains are stable units of replication-timing regulation

Benjamin D. Pope et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks

Francois Aymard et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)

Article Multidisciplinary Sciences

Nesprins: Tissue-Specific Expression of Epsilon and Other Short Isoforms

Nguyen Thuy Duong et al.

PLOS ONE (2014)

Article Cell Biology

Specifying peripheral heterochromatin during nuclear lamina reassembly

Andrey Poleshko et al.

NUCLEUS (2014)

Article Biochemistry & Molecular Biology

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

Jop Kind et al.

Article Biochemistry & Molecular Biology

Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment

Jennifer E. Phillips-Cremins et al.

Review Biochemistry & Molecular Biology

Partners and post-translational modifications of nuclear lamins

Dan N. Simon et al.

CHROMOSOMA (2013)

Review Biochemistry & Molecular Biology

The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatin

Andrea Rothballer et al.

CHROMOSOMA (2013)

Review Biochemistry & Molecular Biology

Nesprins: from the nuclear envelope and beyond

Dipen Rajgor et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2013)

Article Biochemistry & Molecular Biology

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

Wouter Meuleman et al.

GENOME RESEARCH (2013)

Article Cell Biology

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence

Oliver Dreesen et al.

JOURNAL OF CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

Jae-Won Shin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Organization of the Mitotic Chromosome

Natalia Naumova et al.

SCIENCE (2013)

Review Cell Biology

Tissue specificity in the nuclear envelope supports its functional complexity

Jose I. de las Heras et al.

NUCLEUS (2013)

Article Cell Biology

The nuclear envelope LEM-domain protein emerin

Jason M. Berk et al.

NUCLEUS (2013)

Article Biochemistry & Molecular Biology

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

Joseph M. Zullo et al.

Article Biochemistry & Molecular Biology

Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery

Benjamin D. Towbin et al.

Article Biochemistry & Molecular Biology

The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity

Justin Demmerle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation

Yasuhiro Hirano et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Cell Biology

Lamins at a glance

Chin Yee Ho et al.

JOURNAL OF CELL SCIENCE (2012)

Article Biochemistry & Molecular Biology

Nuclear lamina at the crossroads of the cytoplasm and nucleus

Larry Gerace et al.

JOURNAL OF STRUCTURAL BIOLOGY (2012)

Article Multidisciplinary Sciences

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Jesse R. Dixon et al.

NATURE (2012)

Article Multidisciplinary Sciences

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

Hea-Jin Jung et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Cell Biology

The nuclear envelope proteome differs notably between tissues

Nadia Korfali et al.

NUCLEUS (2012)

Article Biochemistry & Molecular Biology

Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function

Maria L. Lombardi et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2011)

Article Cell Biology

A dual role for A-type lamins in DNA double-strand break repair

Abena B. Redwood et al.

CELL CYCLE (2011)

Article Cell Biology

Subnuclear segregation of genes and core promoter factors in myogenesis

Jie Yao et al.

GENES & DEVELOPMENT (2011)

Article Cell Biology

The role of nuclear lamin B1 in cell proliferation and senescence

Takeshi Shimi et al.

GENES & DEVELOPMENT (2011)

Article Developmental Biology

The role of Drosophila Lamin C in muscle function and gene expression

George Dialynas et al.

DEVELOPMENT (2010)

Article Biochemistry & Molecular Biology

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Daan Peric-Hupkes et al.

MOLECULAR CELL (2010)

Article Multidisciplinary Sciences

Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation

Stephanie K. Mewborn et al.

PLOS ONE (2010)

Article Multidisciplinary Sciences

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

G. W. Gant Luxton et al.

SCIENCE (2010)

Article Cell Biology

Nuclear Lamins

Thomas Dechat et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)

Article Cell Biology

Lamin-binding Proteins

Katherine L. Wilson et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)

Article Cell Biology

Chromosome Territories

Thomas Cremer et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)

Article Cell Biology

LINC complexes in health and disease

Alexandre Mejat et al.

NUCLEUS (2010)

Review Cell Biology

Role of A-type lamins in signaling, transcription, and chromatin organization

Vicente Andres et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

The Supramolecular Organization of the C. elegans Nuclear Lamin Filament

Kfir Ben-Harush et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Erez Lieberman-Aiden et al.

SCIENCE (2009)

Article Cell Biology

The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

Dale K. Shumaker et al.

JOURNAL OF CELL BIOLOGY (2008)

Review Cell Biology

Histone modifications and nuclear architecture:: A review

Eva Bartova et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2008)

Article Multidisciplinary Sciences

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

K. L. Reddy et al.

NATURE (2008)

Article Genetics & Heredity

Recruitment to the nuclear periphery can alter expression of genes in human cells

Lee E. Finlan et al.

PLOS GENETICS (2008)

Article Biochemistry & Molecular Biology

High-resolution profiling of histone methylations in the human genome

Artern Barski et al.

Article Biochemistry & Molecular Biology

Solution NMR structure of the barrier-to-autointegration factor-emerin complex

Mengli Cai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemical Research Methods

Detection of in vivo protein-DNA interactions using DamID in mammalian cells

Maartje J. Vogel et al.

NATURE PROTOCOLS (2007)

Review Cell Biology

Barrier-to-autointegration factor - a BAFfling little protein

Ayelet Margalit et al.

TRENDS IN CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology

Sebastian Ulbert et al.

FEBS LETTERS (2006)

Article Cell Biology

Nuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis

I-Hsiung Brandon Chen et al.

BMC CELL BIOLOGY (2006)

Article Multidisciplinary Sciences

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

Dale K. Shumaker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

A mitotic lamin B matrix induced by RanGTP required for spindle assembly

MY Tsai et al.

SCIENCE (2006)

Article Cell Biology

Dynamic properties of germ line-specific lamin B3:: The role of the shortened rod domain

W Schütz et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2005)

Article Multidisciplinary Sciences

Lamin B1 is required for mouse development and nuclear integrity

L Vergnes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Dynamic interaction between BAF and emerin revealed by FRAP, FLIP, and FRET analyses in living HeLa cells

T Shimi et al.

JOURNAL OF STRUCTURAL BIOLOGY (2004)

Review Biochemical Research Methods

Chromatin immunoprecipitation assay

PM Das et al.

BIOTECHNIQUES (2004)

Article Cell Biology

Nup358 integrates nuclear envelope breakdown with kinetochore assembly

D Salina et al.

JOURNAL OF CELL BIOLOGY (2003)

Article Multidisciplinary Sciences

Nuclear membrane proteins with potential disease links found by subtractive proteomics

EC Schirmer et al.

SCIENCE (2003)

Review Cell Biology

Remodelling the walls of the nucleus

B Burke et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Multidisciplinary Sciences

Capturing chromosome conformation

J Dekker et al.

SCIENCE (2002)

Review Biochemistry & Molecular Biology

Inner nuclear membrane proteins: functions and targeting

L Holmer et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2001)

Article Biochemistry & Molecular Biology

LAP2 binds to BAF•DNA complexes:: requirement for the LEM domain and modulation by variable regions

DK Shumaker et al.

EMBO JOURNAL (2001)

Review Genetics & Heredity

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

T Cremer et al.

NATURE REVIEWS GENETICS (2001)

Article Biochemistry & Molecular Biology

MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin

F Lin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)