4.6 Article

Characteristics and Clinical Outcomes of 116,539 Patients Hospitalized with COVID-19-Poland, March-December 2020

Journal

VIRUSES-BASEL
Volume 13, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/v13081458

Keywords

SARS-CoV-2; COVID-19; risk factors; mortality; hospitalization; intensive care unit; COVID-19 prediction ICU; Poland

Categories

Funding

  1. Medical University of Warsaw [NZC/Z/PW1/N/20, PW/Z/5/4/20(1)]
  2. Ministry of Health

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A retrospective analysis of COVID-19 hospitalized patients in Poland from March to December 2020 found that patients over 60 years of age, male gender, and those with cardiovascular diseases or genitourinary system diseases had higher odds of COVID-19-related in-hospital death risk. The presence of at least one comorbidity more than doubled the risk of in-hospital death, emphasizing the importance of managing underlying health conditions during a COVID-19 infection.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19). This study aimed to characterize patients hospitalized with COVID-19 in Poland between March and December 2020, as well as to identify factors associated with COVID 19-related risk of in-hospital death. This retrospective analysis was based on data from the hospital discharge reports on COVID-19 patients hospitalized in Poland between March and December 2020. A total of 116,539 discharge reports on patients hospitalized with COVID-19 were analyzed. Among patients with COVID-19, 21,490 (18.4%) died during hospitalization. Patients over 60 years of age (OR = 7.74; 95%CI: 7.37-8.12; p < 0.001), men (OR = 1.42; 95%CI: 1.38-1.47; p < 0.001) as well as those with cardiovascular diseases (OR = 1.51; 95%CI: 1.46-1.56; p < 0.001) or disease of the genitourinary system (OR = 1.39; 95%CI: 1.31-1.47; p < 0.001) had much higher odds of COVID 19-related risk of in-hospital death. The presence of at least one comorbidity more than doubled the COVID 19-related risk of in-hospital death (OR = 2.23; 95%CI: 2.14-2.32; p < 0.01). The following predictors of admission to ICU were found in multivariable analysis: age over 60 years (OR: 2.03; 95%CI: 1.90-2.16), male sex (OR: 1.79; 95%CI: 1.69-1.89), presence of at least one cardiovascular disease (OR: 1.26; 95%CI: 1.19-1.34), presence of at least one endocrine, nutritional and metabolic disease (OR: 1.17; 95%CI: 1.07-1.28).

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