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Helicobacter pylori eradication: Exploring its impacts on the gastric mucosa

Journal

WORLD JOURNAL OF GASTROENTEROLOGY
Volume 27, Issue 31, Pages 5152-5170

Publisher

BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v27.i31.5152

Keywords

Helicobacter pylori; Gastric mucosa; Histology; Endoscopic findings; Gastrointestinal microbiota; Eradication therapy

Funding

  1. National Natural Science Foundation of China [722211A00352]

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H. pylori infection affects gastric mucosal functions significantly, and eradication can lead to functional recovery.
Helicobacter pylori (H. pylori) infects approximately 50% of all humans globally. Persistent H. pylori infection causes multiple gastric and extragastric diseases, indicating the importance of early diagnosis and timely treatment. H. pylori eradication produces dramatic changes in the gastric mucosa, resulting in restored function. Consequently, to better understand the importance of H. pylori eradication and clarify the subsequent recovery of gastric mucosal functions after eradication, we summarize histological, endoscopic, and gastric microbiota changes to assess the therapeutic effects on the gastric mucosa.

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