Disparities in infant mortality from all-infectious, vaccine-preventable, and non-vaccine preventable diseases in relation to parental education

Background: The burden of infectious diseases in infants is substantial. Parental education has been considered as a critical factor for predicting infant mortality. However, even though some studies have been done about relationship between infectious disease and parent's education level, no researches have been conducted specifically about vaccine-preventable and non-vaccine-preventable disease mortality by parent's educational level. Purpose: This study aimed to compare infant mortality rates from all-infectious diseases, vaccine preventable and non-vaccine-preventable diseases by mother's and father's education levels. Methods: We used 2017 US Linked Birth and Infant Death Data from National Center for Health Statistics, which included 3,153,574 live births and 13,870 deaths. To identify the association between each mother's and father's education level and all-infectious disease, vaccine-preventable disease, and non-vaccine-preventable disease infant mortality, logistic regression analyses were conducted by using educational level 1 as the reference. All-infectious diseases, vaccine-preventable and non-vaccine-preventable diseases were identified by vaccination recommendation of 2017 CDC guideline. Education levels were classified into four groups: level 1, through 12th grade with no diploma; Level 2, high school graduate or GED completed; Level 3, some college credit but no degree or associate degree; and Level 4, bachelor's degree, master's degree, doctorate or professional degree. Results: Higher parents' education level was appreciably associated with lower infant mortality from all cause, all-infectious diseases, vaccine-preventable diseases, and non-vaccine-preventable diseases. Moreover, each mother's and father's education level was correlated to infant mortality due to vaccine-preventable diseases on the whole education level, while all-infectious disease and non vaccine-preventable disease mortality is related with parent's education level only if their education level is fairly high. In other words, the adjusted odds for vaccine-preventable disease mortality were significantly lower than that for all-infectious and non-vaccine-preventable disease mortality at education level 2 and 3 and still smaller at education level 4. Conclusion: These finding implies that each mother's and father's higher education level was associated with lower infant mortality rate from all-infectious diseases, vaccine-preventable diseases, and non vaccine-preventable diseases. Furthermore, each level of mother's and father's education was more likely to be related to infant mortality by vaccine-preventable diseases than that of infant mortality by all infectious diseases, and non-vaccine-preventable diseases. (c) 2021 Elsevier Ltd. All rights reserved.

Automated summary

This study aimed to compare infant mortality rates from all-infectious diseases, vaccine-preventable diseases and non-vaccine-preventable diseases by mother's and father's education levels. Results showed that higher parents' education level was appreciably associated with lower infant mortality from all cause, all-infectious diseases, vaccine-preventable diseases, and non-vaccine-preventable diseases. Moreover, each mother's and father's education level was correlated to infant mortality due to vaccine-preventable diseases on the whole education level.