4.6 Editorial Material

Function Follows Form: Gene Expression and Prenatal Screening

Journal

TRENDS IN MOLECULAR MEDICINE
Volume 27, Issue 8, Pages 725-727

Publisher

CELL PRESS
DOI: 10.1016/j.molmed.2021.06.001

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Funding

  1. NIH [HG200400-04]

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Traditionally, prenatal testing has focused on using imaging to assess fetal anatomy. However, measuring mRNA transcripts in maternal blood can provide a more precise evaluation of fetal function, helping identify pregnancies that require closer monitoring and babies that should be delivered in special care settings.
To date, prenatal testing has relied on imaging to determine fetal 'form' (anatomy). 'Function', as ascertained by measuring fetal or placental mRNA transcripts in maternal blood, has the potential to more precisely determine which pregnancies need closer monitoring and which babies should be delivered in special care settings.

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