Journal
TRENDS IN CELL BIOLOGY
Volume 31, Issue 8, Pages 613-615Publisher
CELL PRESS
DOI: 10.1016/j.tcb.2021.04.006
Keywords
-
Categories
Funding
- National Institutes of Health [AI40646]
- ALSAC
Ask authors/readers for more resources
The study reveals a non-canonical process in which ATG8 proteins can be ligated to phosphatidylserine, potentially leading to different consequences during autophagy.
During autophagy, proteins of the ATG8 family are conjugated to phosphatidylethanolamine (PE) in double-membrane structures called phagophores. Now, Durgan et al. have found that, during the non-canonical process of conjugating ATG8 proteins to single-membrane structures, ATG8 can be ligated to phosphatidylserine. Here, I discuss the potential consequences of their findings.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available