4.7 Review

Engineered Living Materials: Taxonomies and Emerging Trends

Journal

TRENDS IN BIOTECHNOLOGY
Volume 39, Issue 6, Pages 574-583

Publisher

CELL PRESS
DOI: 10.1016/j.tibtech.2020.10.009

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Funding

  1. Defense Advanced Research Projects Agency [HR00111720039]

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The field of engineered living materials (ELMs) at the intersection of synthetic biology and materials science has become a new, standalone discipline, where the fusion of bioengineering and classical materials science has led to significant breakthroughs in the synthesis of complex materials. However, the transdisciplinary nature and rapid growth of the field have made it challenging for holistic comprehension of achievements related to ELM tools, techniques, and applications across disciplines.
At the intersection of synthetic biology and materials science, the field of engineered living materials (ELMs) has evolved into a new, standalone discipline. The fusion of bioengineering's design-build-test-learn approaches with classical materials science has yielded breakthrough innovations in the synthesis of complex, biologically active materials for functional applications in therapeutics, electronics, construction, and beyond. However, the transdisciplinary nature of the ELM field - and its rapid growth - has made holistic comprehension of achievements related to the tools, techniques, and applications of ELMs difficult across disciplines. To this end, this review proposes an emergent taxonomy of ELM research and uses the categorization to discuss current trends and stateof-the-art advancements, significant opportunities, and imminent challenges for scientists and engineers in the field.

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