Calibration-free potentiometric sensing with solid-contact ion-selective electrodes

In recent years, an important aspect of research into the improvement of ion-selective electrodes (ISEs) has been the development of solid-contact ISEs for calibration-free measurements, with the goal of sensors that can be implemented with ease for long-term, in situ analysis with very limited or no maintenance. This review discusses the definition of the term calibration-free in this context, and it gives suggestions as to what types of information should be reported if a claim of calibration-free usage is made. Relevant literature in this field is reviewed, with a focus on different mechanisms of ion-toelectron signal transduction. Different types of redox-active, capacitive, and mixed-mechanism transduction modes are discussed in view of the reproducibility and stability of the potential responses they provide. (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

Research in recent years has focused on the development of solid-contact ISEs for calibration-free measurements in long-term, in situ analysis. This review discusses the definition of calibration-free usage and relevant literature, with a focus on different mechanisms of ion-to-electron signal transduction and different types of transduction modes.