Journal
SYNTHETIC COMMUNICATIONS
Volume 51, Issue 15, Pages 2316-2323Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2021.1933037
Keywords
Acetic acid; amines; ethanol; N-alkylation; xanthate esters
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Funding
- UGC-SAP DRS III
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The N-alkylation of amines by the reaction with xanthate esters in the presence of acetic acid catalyst in ethanol is efficient, environmentally friendly, and a general approach. A probable mechanism for the N-alkylation of amines is proposed in the study.
N-alkylation of amines by the reaction with xanthate esters in the presence of acetic acid catalyst in ethanol is reported. Short reaction time, high yield, general applicability and environmentally benign nature are the noteworthy features of our protocol. The probable mechanism for the formation N-alkylation of amines is proposed.
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