A Review on Synthetic Approaches towards Kavalactones

Kavalactones are classes of alpha-pyrone and 5,6-dihydropyrone derivatives showing various biological activities, and numerous approaches have been reported for the preparation of these molecules. In this review, we discuss the different synthetic approaches towards these naturally occurring lactones, in both racemic and enantiomerically pure forms, that have been reported in the literature to date. It is hoped that this review will assist researchers in the development of additional and efficient synthetic routes towards kavalactones.

Automated summary

This review discusses various synthetic approaches towards kavalactones and aims to assist researchers in developing additional and efficient synthetic routes.