Boron Lewis Pair Mediated C-H Activation and Borylation

In the few past years, the chemistry of frustrated Lewis pairs (FLP) has enabled a plethora of transformations that would otherwise only be possible using transition metal catalysts. Of particular interest are C-H bond activation and borylation reactions, which are the subject of this review. The FLP borylation chemistry is compared with the early borylation methodologies using strongly electrophilic boreniurn ions. We present the mechanism of the C-H borylation using interand intramolecular Lewis pairs, along with some applications of these transformations.

Automated summary

In recent years, the chemistry of frustrated Lewis pairs (FLP) has enabled various transformations, particularly in C-H bond activation and borylation reactions. A comparison is made between FLP borylation chemistry and early borylation methodologies. The mechanism of C-H borylation using inter- and intramolecular Lewis pairs, along with some applications, is presented.