Considering the level of myositis-specific autoantibodies could improve the precision of multiplex assay : lesson from patients with multiple positive results

Summary: Studies have shown that detection of multiple myositis-specific autoantibodies in patients with inflammatory myopathies is less rare than commonly accepted, possibly due to specificity issues with commercially available multiplex immunoassays. True "multiple MSA-positive" patients may exist, though they are likely rare.