Journal
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
Volume 22, Issue 1, Pages 404-428Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14686996.2021.1924044
Keywords
Nanoparticles; magnetic nanoparticles; gold nanoparticles; black phosphorus nanosheets; composite scaffolds; photothermal therapy; tissue engineering
Categories
Funding
- JSPS KAKENHI [19H04475]
- Grants-in-Aid for Scientific Research [19H04475] Funding Source: KAKEN
Ask authors/readers for more resources
Photothermal therapy is a promising method for cancer treatment with less severe side effects. The use of photothermal agents and composite scaffolds can enhance treatment efficacy while minimizing adverse effects, promoting the reconstruction and regeneration of tissues and organs.
Photothermal therapy (PTT) has attracted broad attention as a promising method for cancer therapy with less severe side effects than conventional radiation therapy, chemotherapy and surgical resection. PTT relies on the photoconversion capacity of photothermal agents (PTAs), and a wide variety of nanomaterials have been employed as PTAs for cancer therapy due to their excellent photothermal properties. The PTAs are systematically or locally administered and become enriched in cancer cells to increase ablation efficiency. In recent years, PTAs and three-dimensional scaffolds have been hybridized to realize the local delivery of PTAs for the repeated ablation of cancer cells. Meanwhile, the composite scaffolds can stimulate the reconstruction and regeneration of the functional tissues and organs after ablation of cancer cells. A variety of composite scaffolds of photothermal nanomaterials have been prepared to combine the advantages of different modalities to maximize their therapeutic efficacy with minimal side effects. The synergistic effects make the composite scaffolds attractive for biomedical applications. This review summarizes these latest advances and discusses the future prospects. [GRAPHICS] .
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available