Comment on Individual heterozygosity predicts translocation success in threatened desert tortoises

Scott et al. (Reports, 27 November 2020, p. 1086) bring much-needed attention to species conservation by demonstrating heterozygote superiority among translocated tortoises. However, we believe that their recommended heterozygosity decision rule risks taking conservation genomics backward. We argue that their advice could misguide conservation management aimed at establishing viable populations, and that it can be improved by also assessing the genetic load.

Automated summary

Scott et al. bring attention to species conservation by demonstrating heterozygote superiority among translocated tortoises, but their recommended decision rule may risk setbacks in conservation genomics. Further assessment and improvement are needed to guide conservation management effectively.