Journal
RESPIRATORY MEDICINE
Volume 186, Issue -, Pages -Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.rmed.2021.106531
Keywords
COVID-19 pneumonia; Low dose radiation therapy; Inflammation; Macrophages
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The covid-19 pandemic has greatly impacted countries worldwide, with patients often developing respiratory diseases that could progress to SARS-CoV-2 pneumonia. Severe cases of SARS-CoV-2 pneumonia trigger a systemic inflammatory response, but low-dose radiation therapy can help by reducing inflammation and modulating the immune system, thereby easing the burden on healthcare systems.
The covid-19 pandemic has been affecting many countries across the world and lost precious lives. Most patients suffer from respiratory disease which progresses to the severe acute respiratory syndrome, termed as SARS-CoV-2 pneumonia. A systemic inflammatory response occurs in SARS-CoV-2 pneumonia severely ill patients, The inflammation process if uncontrolled has a detrimental effect, and the release of cytokines play an important role leading to lung fibrosis. Radiation therapy used in low doses has an anti-inflammatory and immunomodulatory effect. Its low cost, wider availability, and decreased risk of acute side effects can reduce the burden on the health care system.
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