Green and catalyst-free synthesis of aminoanthraquinone derivatives in solvent-free conditions

In this study, new derivatives of aminoanthraquinone have been synthesized via one-pot three-component condensation reaction of 1- and 2-amino anthraquinones, triethyl orthoformate and CH-acid compounds without using any solvent or catalyst in mild temperature (50 degrees C). This simple and efficient method yields the desired products in short reaction time (14-50 min) and good to excellent yields (85-96%). Moreover, chemical structures of synthesized products have been entirely confirmed by FT-IR, H-1 and (CNMR)-C-13 and mass spectroscopy and melting points.

Automated summary

In this study, new derivatives of aminoanthraquinone were synthesized efficiently via a one-pot three-component condensation reaction, yielding the desired products in short time with good to excellent yields. The chemical structures of the synthesized products were confirmed using various analytical techniques.