Outcomes of curative-intent radiotherapy in non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD)

Outcomes of non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD n = 587) and interstitial lung disease (ILD n = 34) treated with curative-intent radiotherapy were retrospectively investigated. Presence of ILD but not decreased forced expiratory volume in 1-second correlated with poor overall survival. Increased breathlessness and oxygen requirements after radiotherapy were observed in severe/very severe COPD and ILD. (c) 2021 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 160 (2021) 78-81

Automated summary

The outcomes of NSCLC patients with COPD and ILD treated with curative-intent radiotherapy were retrospectively investigated. Poor overall survival was correlated with the presence of ILD, but not with decreased forced expiratory volume in 1-second. Increased breathlessness and oxygen requirements after radiotherapy were observed in severe/very severe COPD and ILD patients.