4.7 Article

Outcomes of curative-intent radiotherapy in non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD)

Journal

RADIOTHERAPY AND ONCOLOGY
Volume 160, Issue -, Pages 78-81

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2021.04.014

Keywords

NSCLC; COPD; ILD; FEV1; Radiotherapy; Survival

Funding

  1. Manchester Cancer Research Centre, The Christie Charity
  2. University of Manchester
  3. Cancer Research UK [C147/A18083, C147/A25254]

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The outcomes of NSCLC patients with COPD and ILD treated with curative-intent radiotherapy were retrospectively investigated. Poor overall survival was correlated with the presence of ILD, but not with decreased forced expiratory volume in 1-second. Increased breathlessness and oxygen requirements after radiotherapy were observed in severe/very severe COPD and ILD patients.
Outcomes of non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD n = 587) and interstitial lung disease (ILD n = 34) treated with curative-intent radiotherapy were retrospectively investigated. Presence of ILD but not decreased forced expiratory volume in 1-second correlated with poor overall survival. Increased breathlessness and oxygen requirements after radiotherapy were observed in severe/very severe COPD and ILD. (c) 2021 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 160 (2021) 78-81

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