Journal
RADIOLOGIA MEDICA
Volume 126, Issue 12, Pages 1609-1618Publisher
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s11547-021-01412-1
Keywords
Phosphaturic mesenchymal tumors; Oncogenic osteomalacia; Tumor-induced osteomalacia; Fibroblast growth factor 23
Funding
- Universita di Foggia within the CRUI-CARE Agreement
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Phosphaturic mesenchymal tumors (PMTs) are rare neoplasms of soft tissue or bone origin that often result in tumor-induced osteomalacia. They exhibit polymorphic features on radiological and histological examinations, leading to challenges in differential diagnosis with other mesenchymal tumors.
Phosphaturic mesenchymal tumors (PMTs) are rare mesenchymal neoplasms of soft tissue or bone origin that can give rise to a challenge in diagnostic imaging. These tumors are frequently associated with tumor-induced osteomalacia, also called oncogenic osteomalacia, which is a rare paraneoplastic syndrome characterized by ectopic secretion of fibroblast growth factor 23, a hormone that regulates serum phosphate level. PMTs show polymorphic features on both radiological findings and histological examination, causing problems in diagnosis owing to their similarity with other mesenchymal tumors. Thus, this paper aims to describe radiological aspects of PMTs and suggest an imaging pathway for accurate diagnosis throughout the evidence from the literature review.
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