4.8 Article

Disparate regulation of IMD signaling drives sex differences in infection pathology in Drosophila melanogaster

Related references

Note: Only part of the references are listed.
Article Biology

Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

Jason W. Millington et al.

Summary: This study found that a protein-rich diet increases body size in female fruit flies, but not males, by enhancing the activity of the conserved insulin/insulin-like growth factor signaling pathway (IIS). The sex-biased upregulation of IIS activity in females is triggered by a diet-induced increase in stunted mRNA, revealing new sex-specific roles for certain genes. Additionally, the sex determination gene transformer promotes the diet-induced increase in stunted mRNA via the transcriptional coactivator Spargel to regulate the difference in body size plasticity between males and females.

ELIFE (2021)

Article Immunology

Origins of Metabolic Pathology inFrancisella-InfectedDrosophila

Crystal M. Vincent et al.

FRONTIERS IN IMMUNOLOGY (2020)

Editorial Material Immunology

Sex differences in immunity INTRODUCTION

Hanna Lotter et al.

SEMINARS IN IMMUNOPATHOLOGY (2019)

Article Biochemistry & Molecular Biology

The genetic architecture of defence as resistance to and tolerance of bacterial infection in Drosophila melanogaster

Virginia M. Howick et al.

MOLECULAR ECOLOGY (2017)

Review Entomology

Reproduction-Immunity Trade-Offs in Insects

Robin A. Schwenke et al.

ANNUAL REVIEW OF ENTOMOLOGY, VOL 61 (2016)

Article Microbiology

SeXX Matters in Infectious Disease Pathogenesis

Landon G. vom Steeg et al.

PLOS PATHOGENS (2016)

Review Immunology

Sex differences in immune responses

Sabra L. Klein et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Genetics & Heredity

The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size

Elizabeth J. Rideout et al.

PLOS GENETICS (2015)

Article Biology

Sexual antagonism for resistance and tolerance to infection in Drosophila melanogaster

Crystal M. Vincent et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Article Multidisciplinary Sciences

dRYBP Contributes to the Negative Regulation of the Drosophila Imd Pathway

Ricardo Aparicio et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Listeria monocytogenes Infection Causes Metabolic Shifts in Drosophila melanogaster

Moria C. Chambers et al.

PLOS ONE (2012)

Review Multidisciplinary Sciences

Disease Tolerance as a Defense Strategy

Ruslan Medzhitov et al.

SCIENCE (2012)

Article Microbiology

CD200 Receptor Controls Sex-Specific TLR7 Responses to Viral Infection

Guruswamy Karnam et al.

PLOS PATHOGENS (2012)

Review Cell Biology

The struggle for iron - a metal at the host-pathogen interface

Manfred Nairz et al.

CELLULAR MICROBIOLOGY (2010)

Review Microbiology

Molecular mechanisms of Escherichia coli pathogenicity

Matthew A. Croxen et al.

NATURE REVIEWS MICROBIOLOGY (2010)

Article Respiratory System

Adaptive immunity to rhinoviruses: sex and age matter

Melanie L. Carroll et al.

RESPIRATORY RESEARCH (2010)

Article Public, Environmental & Occupational Health

Characterization of Francisella tularensis Strains, Comparing Their Carbon Source Utilization

M. Gyuranecz et al.

ZOONOSES AND PUBLIC HEALTH (2010)

Article Neurosciences

Obesity-Blocking Neurons in Drosophila

Bader Al-Anzi et al.

NEURON (2009)

Article Biology

On sexual dimorphism in immune function

Charles L. Nunn et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2009)

Review Pathology

Sex differences in autoimmune disease from a pathological perspective

DeLisa Fairweather et al.

AMERICAN JOURNAL OF PATHOLOGY (2008)

Article Immunology

Pirk is a negative regulator of the Drosophila Imd pathway

Anni Kleino et al.

JOURNAL OF IMMUNOLOGY (2008)

Article Biochemistry & Molecular Biology

A Signaling Protease Required for Melanization in Drosophila Affects Resistance and Tolerance of Infections

Janelle S. Ayres et al.

PLOS BIOLOGY (2008)

Article Microbiology

A specific primed immune response in Drosophila is dependent on phagocytes

Linh N. Pham et al.

PLOS PATHOGENS (2007)

Review Ecology

Mating and immunity in invertebrates

Mara K. N. Lawniczak et al.

TRENDS IN ECOLOGY & EVOLUTION (2007)

Article Biochemistry & Molecular Biology

Akt and foxo dysregulation contribute to infection-induced wasting in Drosophila

Marc S. Dionne et al.

CURRENT BIOLOGY (2006)

Article Biochemistry & Molecular Biology

The Toll and Imd pathways are the major regulators of the immune response in Drosophila

E De Gregorio et al.

EMBO JOURNAL (2002)

Review Immunology

Drosophila innate immunity: an evolutionary perspective

JA Hoffmann et al.

NATURE IMMUNOLOGY (2002)

Article Biochemistry & Molecular Biology

Interactions between the cellular and humoral immune responses in Drosophila

M Elrod-Erickson et al.

CURRENT BIOLOGY (2000)