4.8 Article

Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer

Related references

Note: Only part of the references are listed.
Article Genetics & Heredity

Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress

Bettina J. Lehman et al.

Summary: The study reveals that CTCF is highly sensitive to diverse forms of stress in human primary cells, leading to changes in its localization and interactions with RNA. The stress-sensitive pool of CTCF protein can be restored through proteasome inhibition. This stress response in CTCF is observed during neuronal differentiation, highlighting its potential role in cell differentiation regulation.

PLOS GENETICS (2021)

Review Multidisciplinary Sciences

The biology, function, and biomedical applications of exosomes

Raghu Kalluri et al.

SCIENCE (2020)

Review Cell Biology

Classical and Nonclassical Intercellular Communication in Senescence and Ageing

Juan Antonio Fafian-Labora et al.

TRENDS IN CELL BIOLOGY (2020)

Review Oncology

How the ageing microenvironment influences tumour progression

Mitchell Fane et al.

NATURE REVIEWS CANCER (2020)

Article Multidisciplinary Sciences

L1 drives IFN in senescent cells and promotes age-associated inflammation

Marco De Cecco et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

Reassessment of Exosome Composition

Dennis K. Jeppesen et al.

Article Biochemistry & Molecular Biology

Transcriptome signature of cellular senescence

Gabriel Casella et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Biochemistry & Molecular Biology

Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF

Anders S. Hansen et al.

MOLECULAR CELL (2019)

Article Biochemistry & Molecular Biology

RNA Interactions Are Essential for CTCF-Mediated Genome Organization

Ricardo Saldana-Meyer et al.

MOLECULAR CELL (2019)

Review Oncology

Unmasking senescence: context-dependent effects of SASP in cancer

Douglas V. Faget et al.

NATURE REVIEWS CANCER (2019)

Article Biochemistry & Molecular Biology

Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer

Quan Zhu et al.

MOLECULAR CELL (2018)

Article Multidisciplinary Sciences

Chromosomal instability drives metastasis through a cytosolic DNA response

Samuel F. Bakhoum et al.

NATURE (2018)

Review Genetics & Heredity

Structural variation in the 3D genome

Malte Spielmann et al.

NATURE REVIEWS GENETICS (2018)

Article Multidisciplinary Sciences

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

Akiko Takahashi et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers

Yu Amanda Guo et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA

Hideharu Hashimoto et al.

MOLECULAR CELL (2017)

Article Multidisciplinary Sciences

Cytoplasmic chromatin triggers inflammation in senescence and cancer

Zhixun Dou et al.

NATURE (2017)

Article Multidisciplinary Sciences

CTCF prevents genomic instability by promoting homologous recombination-directed DNA double-strand break repair

Fengchao Lang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

cGAS is essential for cellular senescence

Hui Yang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Senescent tumor cells lead the collective invasion in thyroid cancer

Young Hwa Kim et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

Masaki Takasugi et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

Akiko Takahashi et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Cohesin Loss Eliminates All Loop Domains

Suhas S. P. Rao et al.

Review Biochemistry & Molecular Biology

Senescence in Health and Disease

Shenghui He et al.

Article Cell & Tissue Engineering

Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle

Aurelie Chiche et al.

CELL STEM CELL (2017)

Review Cell Biology

From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence

Christopher D. Wiley et al.

CELL METABOLISM (2016)

Article Multidisciplinary Sciences

Reorganization of chromosome architecture in replicative cellular senescence

Steven W. Criscione et al.

SCIENCE ADVANCES (2016)

Article Biochemistry & Molecular Biology

Locus-Specific Targeting to the X Chromosome Revealed by the RNA Interactome of CTCF

Johnny T. Kung et al.

MOLECULAR CELL (2015)

Article Multidisciplinary Sciences

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

Francesca Bersani et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Suhas S. P. Rao et al.

Review Cell Biology

Cellular senescence: from physiology to pathology

Daniel Munoz-Espin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Cell Biology

CTCF Haploinsufficiency Destabilizes DNA Methylation and Predisposes to Cancer

Christopher J. Kemp et al.

CELL REPORTS (2014)

Article Cell Biology

Senescent cells harbour features of the cancer epigenome

Hazel A. Cruickshanks et al.

NATURE CELL BIOLOGY (2013)

Article Cell Biology

Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis

Liesbeth C. W. Vredeveld et al.

GENES & DEVELOPMENT (2012)

Article Biochemistry & Molecular Biology

DNA Damage Signaling Triggers Degradation of Histone Methyltransferases through APC/CCdh1 in Senescent Cells

Akiko Takahashi et al.

MOLECULAR CELL (2012)

Article Multidisciplinary Sciences

Loss of Maternal CTCF Is Associated with Peri-Implantation Lethality of Ctcf Null Embryos

James M. Moore et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

David T. Ting et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

Cohesins functionally associate with CTCF on mammalian chromosome arms

Vania Parelho et al.

Article Multidisciplinary Sciences

Cohesin mediates transcriptional insulation by CCCTC-binding factor

Kerstin S. Wendt et al.

NATURE (2008)

Article Multidisciplinary Sciences

CTCF physically links cohesin to chromatin

Eric D. Rubio et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)