Related references
Note: Only part of the references are listed.Macropinocytosis confers resistance to therapies targeting cancer anabolism
Vaishali Jayashankar et al.
NATURE COMMUNICATIONS (2020)
AXL Controls Directed Migration of Mesenchymal Triple-Negative Breast Cancer Cells
Olivier Zajac et al.
CELLS (2020)
Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis
Bryan King et al.
GENES & DEVELOPMENT (2020)
AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network
Afnan Abu-Thuraia et al.
NATURE COMMUNICATIONS (2020)
Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells
Or-Yam Revach et al.
CANCER RESEARCH (2019)
The pervasiveness of macropinocytosis in oncological malignancies
Cosimo Commisso
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2019)
Metabolic functions of macropinocytosis
Wilhelm Palm
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2019)
Challenges for the Clinical Development of PI3K Inhibitors: Strategies to Improve Their Impact in Solid Tumors
Ariella B. Hanker et al.
CANCER DISCOVERY (2019)
PI3Kβ links integrin activation and PI(3,4)P2 production during invadopodial maturation
Zahra Erami et al.
MOLECULAR BIOLOGY OF THE CELL (2019)
EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
Szu-Wei Lee et al.
DEVELOPMENTAL CELL (2019)
TAM receptors, Phosphatidylserine, inflammation, and Cancer
Tal Burstyn-Cohen et al.
CELL COMMUNICATION AND SIGNALING (2019)
The PRIDE database and related tools and resources in 2019: improving support for quantification data
Yasset Perez-Riverol et al.
NUCLEIC ACIDS RESEARCH (2019)
Axl Can Serve as Entry Factor for Lassa Virus Depending on the Functional Glycosylation of Dystroglycan
Chiara Fedeli et al.
JOURNAL OF VIROLOGY (2018)
Actin-Basec Cell Protrusion in a 3D Matrix
Patrick T. Caswell et al.
TRENDS IN CELL BIOLOGY (2018)
A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration
Corallino Salvatore et al.
NATURE COMMUNICATIONS (2018)
PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells
Seong M. Kim et al.
CANCER DISCOVERY (2018)
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression
Marie-Anne Goyette et al.
CELL REPORTS (2018)
Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane: cytoskeleton interface
Christine Chiasson-MacKenzie et al.
GENES & DEVELOPMENT (2018)
A NUMB-EFA6B-ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility
Martina Zobel et al.
JOURNAL OF CELL BIOLOGY (2018)
63PDPredictive and pharmacodynamic biomarkers associated with phase II, selective and orally bioavailable AXL inhibitor bemcentinib across multiple clinical trials
B Holt et al.
ANNALS OF ONCOLOGY (2018)
Dorsal ruffles enhance activation of Akt by growth factors
Sei Yoshida et al.
JOURNAL OF CELL SCIENCE (2018)
Drinking problems: mechanisms of macropinosome formation and maturation
Catherine M. Buckley et al.
FEBS JOURNAL (2017)
Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis
Robert J. Eddy et al.
TRENDS IN CELL BIOLOGY (2017)
Macropinocytosis: A Metabolic Adaptation to nutrient Stress in Cancer
Maria Victoria Recouvreux et al.
FRONTIERS IN ENDOCRINOLOGY (2017)
AXL-Driven EMT State as a Targetable Conduit in Cancer
Jane Antony et al.
CANCER RESEARCH (2017)
Emerging Biological Principles of Metastasis
Arthur W. Lambert et al.
CELL (2017)
EMT, cell plasticity and metastasis
Christine L. Chaffer et al.
CANCER AND METASTASIS REVIEWS (2016)
Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase
Stanley G. Kimani et al.
CELL COMMUNICATION AND SIGNALING (2016)
Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo
Julia Onken et al.
ONCOTARGET (2016)
Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response
Viralkumar Davra et al.
CANCERS (2016)
The Receptor Tyrosine Kinase AXL in Cancer Progression
Erinn B. Rankin et al.
CANCERS (2016)
Growth factor signaling to mTORC1 by amino acid-laden macropinosomes
Sei Yoshida et al.
JOURNAL OF CELL BIOLOGY (2015)
Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes
Jean-Philippe Lambert et al.
JOURNAL OF PROTEOMICS (2015)
Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression
Bo Sun et al.
BIOMEDICAL REPORTS (2015)
The receptor tyrosine kinase Axl in cancer: Biological functions and therapeutic implications
Juliano D. Paccez et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Receptor Tyrosine Kinases, TYRO3, AXL, and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-induced Activation
Wen-I Tsou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1
James B. Reinecke et al.
JOURNAL OF CELL SCIENCE (2014)
Diversification of TAM receptor tyrosine kinase function
Anna Zagorska et al.
NATURE IMMUNOLOGY (2014)
Determining the macropinocytic index of cells through a quantitative image-based assay
Cosimo Commisso et al.
NATURE PROTOCOLS (2014)
AXL kinase as a novel target for cancer therapy
Xiaoliang Wu et al.
ONCOTARGET (2014)
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities
Erin D. Lew et al.
ELIFE (2014)
TAM receptors in apoptotic cell clearance, autoimmunity, and cancer
Khanh-Quynh Nguyen et al.
AUTOIMMUNITY (2013)
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
Cosimo Commisso et al.
NATURE (2013)
First Axl inhibitor enters clinical trials
Cormac Sheridan
NATURE BIOTECHNOLOGY (2013)
Endocytosis of Receptor Tyrosine Kinases
Lai Kuan Goh et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Effects of Membrane Trafficking on Signaling by Receptor Tyrosine Kinases
Marta Miaczynska
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
Kyle J. Roux et al.
JOURNAL OF CELL BIOLOGY (2012)
Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complex
Yu Wang et al.
JOURNAL OF CELL BIOLOGY (2012)
Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor
S. Babak Azimifar et al.
JOURNAL OF CELL SCIENCE (2012)
Functions and Regulation of Circular Dorsal Ruffles
Jing-Ling Hoon et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration
Zhizhan Gu et al.
JOURNAL OF CELL BIOLOGY (2011)
The Tyro3 Receptor Kinase Axl Enhances Macropinocytosis of Zaire Ebolavirus
Catherine L. Hunt et al.
JOURNAL OF VIROLOGY (2011)
TAM receptors and the clearance of apoptotic cells
Greg Lemke et al.
CLEARANCE OF DYING CELLS IN HEALTHY AND DISEASED IMMUNE SYSTEMS (2010)
AXL Is an Essential Factor and Therapeutic Target for Metastatic Ovarian Cancer
Erinn B. Rankin et al.
CANCER RESEARCH (2010)
Dorsal Ruffle Microdomains Potentiate Met Receptor Tyrosine Kinase Signaling and Down-regulation
Jasmine V. Abella et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling
Mirkka Koivusalo et al.
JOURNAL OF CELL BIOLOGY (2010)
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
Christine Gjerdrum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
EMT, the cytoskeleton, and cancer cell invasion
Mahmut Yilmaz et al.
CANCER AND METASTASIS REVIEWS (2009)
Adhesion signaling - crosstalk between integrins, Src and Rho
Stephan Huveneers et al.
JOURNAL OF CELL SCIENCE (2009)
Axl and growth arrest - Specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme
Markus Hutterer et al.
CLINICAL CANCER RESEARCH (2008)
Regulation of the actin cytoskeleton in cancer cell migration and invasion
Hideki Yamaguchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats
Emmani B. M. Nascimento et al.
DIABETES (2006)
Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival
P Vajkoczy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization
JD Orth et al.
CANCER RESEARCH (2006)
Analysis of Gas6 in human platelets and plasma
I Balogh et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
The Rab5 effector rabankyrin-5 regulates and coordinates different endocytic mechanisms
C Schnatwinkel et al.
PLOS BIOLOGY (2004)
Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles
R Buccione et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases
L Lanzetti et al.
NATURE (2004)
A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells
EW Krueger et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Share Paper
