Journal
GASTROENTEROLOGY
Volume 150, Issue 8, Pages 1786-1797Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.gastro.2016.02.043
Keywords
Clinical Profiles; Alcoholic Liver Disease; Asia; Europe; North America
Categories
Funding
- Veterans Affairs Research and Administration [1I01CX000361]
- United States Department of Defense [W81XWH-12-1-0497]
- NIH/NIAAA [5U01AA018389]
Ask authors/readers for more resources
Alcoholic liver diseases comprise a spectrum of clinical disorders and changes in liver tissue that can be detected by pathology analysis. These range from steatosis to more severe signs and symptoms of liver disease associated with inflammation, such as those observed in patients with alcoholic hepatitis or cirrhosis. Although the relationship between alcohol consumption and liver disease is well established, severe alcohol-related morbidities develop in only a minority of people who consume alcohol in excess. Inter-individual differences in susceptibility to the toxic effects of alcohol have been studied extensively-they include pattern of alcohol consumption, sex, environmental factors (such as diet), and genetic factors, which vary widely among different parts of the world. Alcoholic liver disease is becoming more common in many parts of Asia, but is decreasing in Western Europe. Treatment approaches, including availability of medications, models of care, and approach to transplantation, differ among regions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available