4.7 Review

A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents

Related references

Note: Only part of the references are listed.
Review Pharmacology & Pharmacy

COVID-19: A Case for Inhibiting NLRP3 Inflammasome, Suppression of Inflammation with Curcumin?

Ali Saeedi-Boroujeni et al.

Summary: Curcumin, the active ingredient in turmeric, exhibits anti-inflammatory and anti-inflammasome properties, making it a potential candidate for the treatment of COVID-19 infection due to its regulation of intracellular signaling pathways involved in inflammation.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2021)

Article Immunology

Miconia albicans and Curcuma longa herbal medicines positively modulate joint pain, function and inflammation in patients with osteoarthritis: a clinical study

Thiago P. O. Gomes et al.

Summary: This study found that the treatment of knee osteoarthritis with Curcuma longa and Miconia albicans had comparable effects to ibuprofen, significantly reducing pain and improving patient function.

INFLAMMOPHARMACOLOGY (2021)

Review Medicine, Research & Experimental

Will curcumin nanosystems be the next promising antiviral alternatives in COVID-19 treatment trials?

Douglas Dourado et al.

Summary: Curcumin and its nanostructured systems show potential as antiviral keys for treating SARS-CoV-2, with the possibility of improving treatment efficacy by increasing bioavailability and therapeutic efficiency.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Cell & Tissue Engineering

Curcumin Supplementation Enhances Bone Marrow Mesenchymal Stem Cells to Promote the Anabolism of Articular Chondrocytes and Cartilage Repair

Rui Zhang et al.

Summary: This study investigated the effects of curcumin on the therapeutic effects of BMSCs in osteoarthritis, finding that curcumin supplementation enhanced the proliferation, migration, and anabolic gene expression of articular chondrocytes when cocultured with BMSCs, leading to improved cartilage repair and slowed OA progression.

CELL TRANSPLANTATION (2021)

Article Dentistry, Oral Surgery & Medicine

Oral nano-curcuminon gingival inflammation in patients with gingivitis and mild periodontitis

Meisam Malekzadeh et al.

Summary: This study evaluated the effects of oral nano-curcumin on gingival inflammation in patients with gingivitis and mild periodontitis, finding that nano-curcumin has positive effects on reducing inflammation and gingival bleeding. Nano-curcumin capsules with systemic target site have higher bioavailability than topical forms.

CLINICAL AND EXPERIMENTAL DENTAL RESEARCH (2021)

Review Biochemistry & Molecular Biology

Mutual Two-Way Interactions of Curcumin and Gut Microbiota

Ryszard Pluta et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Pharmacology & Pharmacy

Curcumin for the Management of Periodontal Diseases: A Review

Fatemeh Forouzanfar et al.

CURRENT PHARMACEUTICAL DESIGN (2020)

Article Integrative & Complementary Medicine

New concentration of curcumin orabase in recurrent aphthous stomatitis: A randomized, controlled clinical trial

Seyed Javad Kia et al.

JOURNAL OF HERBAL MEDICINE (2020)

Review Integrative & Complementary Medicine

Biochemistry, Safety, Pharmacological Activities, and Clinical Applications of Turmeric: A Mechanistic Review

Rabia Shabir Ahmad et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2020)

Review Food Science & Technology

Curcumin (a constituent of turmeric): New treatment option against COVID-19

Fatemeh Babaei et al.

FOOD SCIENCE & NUTRITION (2020)

Review Nanoscience & Nanotechnology

Review of Curcumin Physicochemical Targeting Delivery System

Lanmei Li et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Integrative & Complementary Medicine

The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial

Neda Jamali et al.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2020)

Review Cell Biology

Evidence of curcumin and curcumin analogue effects in skin diseases: A narrative review

Yunes Panahi et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Article Biotechnology & Applied Microbiology

The effect of chrysin-curcumin-loaded nanofibres on the wound-healing process in male rats

Zoheyr Mohammadi et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

Article Immunology

Curcumin attenuates collagen-induced rat arthritis via anti-inflammatory and apoptotic effects

Qirui Wang et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2019)

Article Integrative & Complementary Medicine

Curcumin Inhibits Joint Contracture through PTEN Demethylation and Targeting PI3K/Akt/mTOR Pathway in Myofibroblasts from Human Joint Capsule

Ze Zhuang et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2019)

Article Pharmacology & Pharmacy

Antimicrobial Activity of Curcuma longa L. Extract on Periodontal Pathogens

Mohammad Jalaluddin et al.

JOURNAL OF PHARMACY AND BIOALLIED SCIENCES (2019)

Article Cardiac & Cardiovascular Systems

Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases

Kana Shimizu et al.

EUROPEAN CARDIOLOGY REVIEW (2019)

Article Integrative & Complementary Medicine

Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study

Armine Haroyan et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)

Review Dermatology

Turmeric: A condiment, cosmetic and cure

Hima Gopinath et al.

INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY (2018)

Review Pharmacology & Pharmacy

Curcumin in turmeric: Basic and clinical evidence for a potential role in analgesia

U. J. Eke-Okoro et al.

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2018)

Review Pharmacology & Pharmacy

The clinical efficacy of curcumin-containing nutraceuticals: An overview of systematic reviews

Ester Pagano et al.

PHARMACOLOGICAL RESEARCH (2018)

Review Chemistry, Medicinal

Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review

Vahid Soleimani et al.

PHYTOTHERAPY RESEARCH (2018)

Article Dermatology

Turmeric tonic as a treatment in scalp psoriasis: A randomized placebo-control clinical trial

Parichehr Bahraini et al.

JOURNAL OF COSMETIC DERMATOLOGY (2018)

Article Dentistry, Oral Surgery & Medicine

Protective effect and related mechanisms of curcumin in rat experimental periodontitis

Chang-Jie Xiao et al.

HEAD & FACE MEDICINE (2018)

Review Agriculture, Dairy & Animal Science

The crucial roles of inflammatory mediators in inflammation: A review

L. A. Abdulkhaleq et al.

VETERINARY WORLD (2018)

Article Cell Biology

Curcumin Protects Skin against UVB-Induced Cytotoxicity via the Keap1-Nrf2 Pathway: The Use of a Microemulsion Delivery System

Maya Ben Yehuda Greenwald et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Editorial Material Oncology

Curcumin: A Natural Multitarget Treatment for Pancreatic Cancer

Amirhossein Sahebkar

INTEGRATIVE CANCER THERAPIES (2016)

Article Pharmacology & Pharmacy

Emu oil based nano-emulgel for topical delivery of curcumin

Manish Kumar Jeengar et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)

Article Veterinary Sciences

Therapeutic effect of topical application of curcumin during treatment of radiation burns in a mini-pig model

Joongsun Kim et al.

JOURNAL OF VETERINARY SCIENCE (2016)

Article Biochemistry & Molecular Biology

Protective Effect of Curcumin Against Acute Ultraviolet B Irradiation-induced Photo-damage

Huaping Li et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2016)

Article Chemistry, Medicinal

Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial

Sepideh Rahmani et al.

PHYTOTHERAPY RESEARCH (2016)

Review Integrative & Complementary Medicine

Clinical efficacy of turmeric use in gingivitis: A comprehensive review

Karissa A. Stoyell et al.

Complementary Therapies in Clinical Practice (2016)

Article Physiology

Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS)

Lesley M. Nicol et al.

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2015)

Article Biotechnology & Applied Microbiology

Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis Vulgaris

Emiliano Antiga et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Article Pharmacology & Pharmacy

Effect of curcumin on diabetic peripheral neuropathic pain: Possible involvement of opioid system

Hamid R. Banafshe et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2014)

Article Nutrition & Dietetics

Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial

Franchek Drobnic et al.

JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2014)

Article Chemistry, Medicinal

Curcuminoid Treatment for Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Trial

Yunes Panahi et al.

PHYTOTHERAPY RESEARCH (2014)

Review Pharmacology & Pharmacy

Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

Subash C. Gupta et al.

AAPS JOURNAL (2013)

Article Dentistry, Oral Surgery & Medicine

Curcumin inhibits inflammatory response and bone loss during experimental periodontitis in rats

Te Zhou et al.

ACTA ODONTOLOGICA SCANDINAVICA (2013)

Review Biochemistry & Molecular Biology

Curcumin in inflammatory diseases

Adeeb Shehzad et al.

BIOFACTORS (2013)

Review Pharmacology & Pharmacy

Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers

Bharat B. Aggarwal et al.

BRITISH JOURNAL OF PHARMACOLOGY (2013)

Article Medicine, General & Internal

Curcumin Attenuates Diabetic Neuropathic Pain by Downregulating TNF-alpha in a Rat Model

Yue Li et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2013)

Article Gastroenterology & Hepatology

Tolerability of Curcumin in Pediatric Inflammatory Bowel Disease: A Forced-Dose Titration Study

David L. Suskind et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2013)

Article Rheumatology

Evidence that TNF-β ( lymphotoxin α) can activate the inflammatory environment in human chondrocytes

Constanze Buhrmann et al.

ARTHRITIS RESEARCH & THERAPY (2013)

Review Biochemistry & Molecular Biology

Renoprotective effect of the antioxidant curcumin: Recent findings

Joyce Trujillo et al.

REDOX BIOLOGY (2013)

Article Behavioral Sciences

Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats

Hanan Naeim Attia et al.

BEHAVIOURAL PHARMACOLOGY (2012)

Review Gastroenterology & Hepatology

Curcumin and Inflammatory Bowel Disease: Biological Mechanisms and Clinical Implication

Tauseef Ali et al.

DIGESTION (2012)

Article Food Science & Technology

Antinociceptiye Profiles and Mechanisms of Orally Administered Curcumin in Various Pain Models

Soo-Hyun Park et al.

JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY (2012)

Article Clinical Neurology

Evidence for the Participation of ATP-sensitive Potassium Channels in the Antinociceptive Effect of Curcumin

Marco Antonio De Paz-Campos et al.

KOREAN JOURNAL OF PAIN (2012)

Article Pharmacology & Pharmacy

An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L

Vijayastelter B. Liju et al.

INDIAN JOURNAL OF PHARMACOLOGY (2011)

Review Biochemistry & Molecular Biology

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

Purusotam Basnet et al.

MOLECULES (2011)

Article Multidisciplinary Sciences

Interleukin-1 beta-Induced Extracellular Matrix Degradation and Glycosaminoglycan Release Is Inhibited by Curcumin in an Explant Model of Cartilage Inflammation

Abigail L. Clutterbuck et al.

NATURAL COMPOUNDS AND THEIR ROLE IN APOPTOTIC CELL SIGNALING PATHWAYS (2009)

Review Biochemistry & Molecular Biology

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

Bharat B. Aggarwal et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)

Article Integrative & Complementary Medicine

Efficacy and Safety of Curcuma domestica Extracts in Patients with Knee Osteoarthritis

Vilai Kuptniratsaikul et al.

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2009)

Review Chemistry, Physical

Photophysics, photochemistry and photobiology of curcumin: Studies from organic solutions, bio-mimetics and living cells

K. Indira Priyadarsini

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS (2009)

Article Chemistry, Medicinal

Evaluation of Antihyperalgesic Effect of Curcumin on Formalin-Induced Orofacial Pain in Rat

Niti Mittal et al.

PHYTOTHERAPY RESEARCH (2009)

Review Dermatology

Inflammation in wound repair: Molecular and cellular mechanisms

Sabine A. Eming et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)

Article Dermatology

Contact urticaria from curcumin

Melinda Liddle et al.

DERMATITIS (2006)

Article Gastroenterology & Hepatology

Curcumin maintenance therapy for ulcerative colitis: Randomized, multicenter, double-blind, placebo-controlled trial

Hiroyuki Hanai et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Agriculture, Multidisciplinary

Effects of ingested turmeric oleoresin on glucose and lipid metabolisms in obese diabetic mice: A DNA Microarray study

Shinichi Honda et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)

Article Chemistry, Multidisciplinary

Curcumin regulated shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis

Ming Zhang et al.

ACTA PHARMACOLOGICA SINICA (2006)

Article Pharmacology & Pharmacy

Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain

S Sharma et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2006)

Article Gastroenterology & Hepatology

Curcumin therapy in inflammatory bowel disease: A pilot study

PR Holt et al.

DIGESTIVE DISEASES AND SCIENCES (2005)

Article Pharmacology & Pharmacy

The effects of curcumin on depressive-like behaviors in mice

Y Xu et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2005)

Article Biochemistry & Molecular Biology

Curcumin for malaria therapy

RC Reddy et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Review Integrative & Complementary Medicine

Biological basis for the use of botanicals in osteoarthritis and rheumatoid arthritis: A review

S Ahmed et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2005)

Article Integrative & Complementary Medicine

Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: A pilot study

R Bundy et al.

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2004)

Article Biochemistry & Molecular Biology

Hepatoprotective effect of sesquiterpenes in turmeric

M Miyakoshi et al.

BIOFACTORS (2004)

Article Biotechnology & Applied Microbiology

Antimutagenic potential of curcumin on chromosomal aberrations in Wistar rats

Y Shukla et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2002)

Article Critical Care Medicine

Protective effects of curcumin against oxidative damage on skin cells in vitro: Its implication for wound healing

TT Phan et al.

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE (2001)

Article Parasitology

Biological activities of Curcuma longa L.

CAC Araújo et al.

MEMORIAS DO INSTITUTO OSWALDO CRUZ (2001)