Targeting Parasympathetic Activity to Improve Autonomic Tone and Clinical Outcomes

In this review we will briefly summarize the evidence that autonomic imbalance, more specifically reduced parasympathetic activity to the heart, generates and/or maintains many cardiorespiratory diseases and will discuss mechanisms and sites, from myocytes to the brain, that are potential translational targets for restoring parasympathetic activity and improving cardiorespiratory health.

Automated summary

This review summarizes the evidence linking autonomic imbalance to cardiorespiratory diseases, with a focus on reduced parasympathetic activity. It also discusses potential mechanisms and targets for restoring parasympathetic activity and improving cardiorespiratory health, from myocytes to the brain.