Related references
Note: Only part of the references are listed.Calcium modulation of cardiac sodium channels
Christopher N. Johnson
JOURNAL OF PHYSIOLOGY-LONDON (2020)
PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts
Shanna Hamilton et al.
JOURNAL OF PHYSIOLOGY-LONDON (2020)
Structure of the Cardiac Sodium Channel
Daohua Jiang et al.
CELL (2020)
Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics
Guoxia Liu et al.
NATURE (2020)
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1
Manuela Mura et al.
STEM CELL RESEARCH (2020)
Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy
Raffaele Coppini et al.
CARDIOVASCULAR RESEARCH (2020)
Heritable arrhythmia syndromes associated with abnormal cardiac sodium channel function: ionic and non-ionic mechanisms
Mathilde R. Rivaud et al.
CARDIOVASCULAR RESEARCH (2020)
Modulation of the cardiac Na+-Ca2+ exchanger by cytoplasmic protons: Molecular mechanisms and physiological implications
Kyle Scranton et al.
CELL CALCIUM (2020)
Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue
Zsofia Kohajda et al.
FRONTIERS IN PHARMACOLOGY (2020)
Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities
Cristian Trovato et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)
Inherited cardiac arrhythmias
Peter J. Schwartz et al.
NATURE REVIEWS DISEASE PRIMERS (2020)
Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies
Ka Hou Christien Li et al.
IJC HEART & VASCULATURE (2020)
Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice
Steffen Pabel et al.
BASIC RESEARCH IN CARDIOLOGY (2020)
Chronic in vivo angiotensin II administration differentially modulates the slow delayed rectifier channels in atrial and ventricular myocytes
Dimitar P. Zankov et al.
HEART RHYTHM (2019)
Atrial Ca2+/calmodulin-dependent protein kinase II: A druggable master switch of atrial fibrillation-associated atrial remodeling?
Dobromir Dobrev
HEART RHYTHM (2019)
Animal models of arrhythmia: classic electrophysiology to genetically modified large animals
Sebastian Clauss et al.
NATURE REVIEWS CARDIOLOGY (2019)
Extracellular ATP and -NAD alter electrical properties and cholinergic effects in the rat heart in age-specific manner
Ksenia B. Pustovit et al.
PURINERGIC SIGNALLING (2019)
Cardiac fibrosis: potential therapeutic targets
Shuin Park et al.
TRANSLATIONAL RESEARCH (2019)
Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D
Xin Zhou et al.
FRONTIERS IN PHYSIOLOGY (2019)
β-Adrenergic Receptor Stimulation and Alternans in the Border Zone of a Healed Infarct: An ex vivo Study and Computational Investigation of Arrhythmogenesis
Jakub Tomek et al.
FRONTIERS IN PHYSIOLOGY (2019)
Modeling Reentry in the Short QT Syndrome With Human-Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets
Rami Shinnawi et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)
Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue
Sung-Jin Park et al.
CIRCULATION (2019)
Differentiating Right- and Left-Sided Outflow Tract Ventricular Arrhythmias: Classical ECG Signatures and Prediction Algorithms
Robert D. Anderson et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2019)
Transcriptional and Epigenetic Regulation of Cardiac Electrophysiology
Jesus Jimenez et al.
PEDIATRIC CARDIOLOGY (2019)
Human Induced Pluripotent Stem-Cell-Derived Cardiomyocytes as Models for Genetic Cardiomyopathies
Andreas Brodehl et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Inherited Cardiac Arrhythmias and Channelopathies
Jessica Kline et al.
MEDICAL CLINICS OF NORTH AMERICA (2019)
A Distinct Pool of Nav1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes
Jean-Sebastien Rougier et al.
FRONTIERS IN PHYSIOLOGY (2019)
Differential Modulation of IK and ICa,L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria
Laura Martinez-Mateu et al.
FRONTIERS IN PHYSIOLOGY (2019)
Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting
David G. Strauss et al.
THERAPEUTIC INNOVATION & REGULATORY SCIENCE (2019)
'Mature' resting membrane potentials in hiPSC-CMs: fact or artefact?
Arie O. Verkerk et al.
EUROPACE (2019)
High arrhythmic risk in antero-septal acute myocardial ischemia is explained by increased transmural reentry occurrence
Hector Martinez-Navarro et al.
SCIENTIFIC REPORTS (2019)
Transient outward K+ current can strongly modulate action potential duration and initiate alternans in the human atrium
Haibo Ni et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2019)
Drug potency on inhibiting late Na+ current is sensitive to gating modifier and current region where drug effects were measured
Min Wu et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2019)
Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility
Katja E. Odening et al.
EUROPEAN HEART JOURNAL (2019)
Absence of Functional Nav1.8 Channels in Non-diseased Atrial and Ventricular Cardiomyocytes
Simona Casini et al.
CARDIOVASCULAR DRUGS AND THERAPY (2019)
Channelopathies That Lead to Sudden Cardiac Death: Clinicaland Genetic Aspects
Jonathan R. Skinner et al.
HEART LUNG AND CIRCULATION (2019)
Calcium/calmodulin-dependent protein kinase II causes atrial structural remodeling associated with atrial fibrillation and heart failure
Zhao Liu et al.
HEART RHYTHM (2019)
Generation of human induced pluripotent stem cell line carrying SCN5AC2204 > T Brugada mutation (MUSli009-A-1) introduced by CRISPR/Cas9-mediated genome editing
Paweorn Angsutararux et al.
STEM CELL RESEARCH (2019)
R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome
Fernanda C. P. Mesquita et al.
SCIENTIFIC REPORTS (2019)
Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block
Jakub Tomek et al.
ELIFE (2019)
The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy
Shakil Ahmad et al.
ESC HEART FAILURE (2019)
Familial Sinus Node Disease Caused by a Gain of GIRK (G-Protein Activated Inwardly Rectifying K+ Channel) Channel Function
Johanna Kuss et al.
CIRCULATION-GENOMIC AND PRECISION MEDICINE (2019)
From Bernstein's rheotome to Neher-Sakmann's patch electrode. The action potential
Edward Carmeliet
PHYSIOLOGICAL REPORTS (2019)
Cardiac structure and function in elite Native Hawaiian and Pacific Islander Rugby Football League athletes: an exploratory study
Christopher Johnson et al.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING (2018)
Influence of genetic modifiers on sudden cardiac death cases
Tina Jenewein et al.
INTERNATIONAL JOURNAL OF LEGAL MEDICINE (2018)
Differential effects of inhibitory G protein isoforms on G protein-gated inwardly rectifying K+ currents in adult murine atria
Muriel Nobles et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2018)
From ionic to cellular variability in human atrial myocytes: an integrative computational and experimental study
Anna Muszkiewicz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)
Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K-2P) channels in murine disease models: focus on TASK-1
Felix Wiedmann et al.
BASIC RESEARCH IN CARDIOLOGY (2018)
The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations
Smiruthi Ramasubramanian et al.
BIOPHYSICAL JOURNAL (2018)
Metformin restores electrophysiology of small conductance calcium-activated potassium channels in the atrium of GK diabetic rats
Xi Fu et al.
BMC CARDIOVASCULAR DISORDERS (2018)
Noradrenaline up-regulates volume-regulated chloride current by PKA-independent cAMP/exchange protein activated by cAMP pathway in human atrial myocytes
Guo-Sheng Xiao et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium
Cecilia Ferrantini et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Comparison of the effects of I-K,I-ACh, I-Kr, and I-Na block in conscious dogs with atrial fibrillation and on action potentials in remodeled atrial trabeculae
Viktor Juhasz et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2018)
Mutations in voltage-gated L-type calcium channel: implications in cardiac arrhythmia
Qing Zhang et al.
CHANNELS (2018)
Heart Disease and Stroke Statistics-2018 Update A Report From the American Heart Association
Emelia J. Benjamin et al.
CIRCULATION (2018)
Aging Modulates the Substrate and Triggers Remodeling in Atrial Fibrillation
Yung-Kuo Lin et al.
CIRCULATION JOURNAL (2018)
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists
Priyanka Garg et al.
CIRCULATION RESEARCH (2018)
Sex Differences in Cardiac Arrhythmias Clinical and Research Implications
Ashkan Ehdaie et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2018)
Differential Expression and Remodeling of Transient Outward Potassium Currents in Human Left Ventricles
Eric K. Johnson et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2018)
QTc prolongation in short-term treatment of schizophrenia patients: effects of different antipsychotics and genetic factors
Ilja Spellmann et al.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2018)
Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation
Jordi Heijman et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2018)
O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts
Peng Yu et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2018)
Hydrogen sulphide increases pulmonary veins and atrial arrhythmogenesis with activation of protein kinase C
Chao-Shun Chan et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Sudden cardiac death in J wave syndrome with short QT associated to a novel mutation in Na-v 1.8 coding gene SCN10A: First case report for a possible pharmacogenomic role
Giuseppe Di Stolfo et al.
JOURNAL OF ELECTROCARDIOLOGY (2018)
A double-blind, randomised, placebo-controlled, cross-over study assessing the use of XEN-D0103 in patients with paroxysmal atrial fibrillation and implanted pacemakers allowing continuous beat-to-beat monitoring of drug efficacy
S. R. Shunmugam et al.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2018)
A contemporary view of atrioventricular nodal physiology
Steven M. Markowitz et al.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2018)
Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics
Kylie A. Beattie et al.
JOURNAL OF PHYSIOLOGY-LONDON (2018)
Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals
Oleg E. Osadchii
PLOS ONE (2018)
Genome Editing in Induced Pluripotent Stem Cells using CRISPR/Cas9
Ronen Ben Jehuda et al.
STEM CELL REVIEWS AND REPORTS (2018)
The genetic architecture of long QT syndrome: A critical reappraisal
John R. Giudicessi et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2018)
Relationship between KCNQ1 (LQT1) and KCNH2 (LQT2) gene mutations and sudden death during illegal drug use
Sayaka Nagasawa et al.
SCIENTIFIC REPORTS (2018)
Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) Increases Small-Conductance Ca2+-Activated K+ Current in Patients with Chronic Atrial Fibrillation
Xuehui Fan et al.
MEDICAL SCIENCE MONITOR (2018)
Genome Editing in Induced Pluripotent Stem Cells using CRISPR/Cas9
Ronen Ben Jehuda et al.
STEM CELL REVIEWS AND REPORTS (2018)
Automatic Optimization of an in Silico Model of Human iPSC Derived Cardiomyocytes Recapitulating Calcium Handling Abnormalities
Michelangelo Paci et al.
FRONTIERS IN PHYSIOLOGY (2018)
Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium
Marine E. Martinez et al.
FRONTIERS IN PHYSIOLOGY (2018)
Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling
Jussi T. Koivumaki et al.
FRONTIERS IN PHYSIOLOGY (2018)
A Heart for Diversity: Simulating Variability in Cardiac Arrhythmia Research
Haibo Ni et al.
FRONTIERS IN PHYSIOLOGY (2018)
Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes
Andras Horvath et al.
STEM CELL REPORTS (2018)
Long-term Outcomes of Pediatric-Onset Hypertrophic Cardiomyopathy and Age-Specific Risk Factors for Lethal Arrhythmic Events
Niccolo Maurizi et al.
JAMA CARDIOLOGY (2018)
Rat atrial engineered heart tissue: a new in vitro model to study atrial biology
Julia Krause et al.
BASIC RESEARCH IN CARDIOLOGY (2018)
Cardiac fibrosis: new insights into the pathogenesis
Zhen-Guo Ma et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2018)
Unique Ca2+-Cycling Protein Abundance and Regulation Sustains Local Ca2+ Releases and Spontaneous Firing of Rabbit Sinoatrial Node Cells
Tatiana M. Vinogradova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Left atrial thrombus despite continuous direct oral anticoagulant or warfarin therapy in patients with atrial fibrillation: insights into rates and timing of thrombus resolution
Michael S. Wu et al.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2018)
Purkinje physiology and pathophysiology
Penelope A. Boyden
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2018)
Present Status of Brugada Syndrome JACC State-of-the-Art Review
Josep Brugada et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)
Clinical Diagnosis, Imaging, and Genetics of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia JACC State-of-the-Art Review
Estelle Gandjbakhch et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)
Satellite cells delivered in their niche efficiently generate functional myotubes in three-dimensional cell culture
Johanna Prueller et al.
PLOS ONE (2018)
Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges
Marcia R. S. S. Vagos et al.
FRONTIERS IN PHYSIOLOGY (2018)
Myocyte [Na+](i) Dysregulation in Heart Failure and Diabetic Cardiomyopathy
Sanda Despa
FRONTIERS IN PHYSIOLOGY (2018)
Modulation of Cardiac Alternans by Altered Sarcoplasmic Reticulum Calcium Release: A Simulation Study
Jakub Tomek et al.
FRONTIERS IN PHYSIOLOGY (2018)
Modernized Classification of Cardiac Antiarrhythmic Drugs
Ming Lei et al.
CIRCULATION (2018)
Heart Failure Differentially Modulates the Effects of Ivabradine on the Electrical Activity of the Sinoatrial Node and Pulmonary Veins
Chao-Shun Chan et al.
JOURNAL OF CARDIAC FAILURE (2018)
The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction
Dennis M. Abraham et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Effects of β-subunit on gating of a potassium ion channel: Molecular simulations of cardiac IKs activation
Jiajing Xu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2018)
Corrected QT Interval Prolongation in Psychopharmacological Treatment and Its Modulation by Genetic Variation
Filippo Corponi et al.
NEUROPSYCHOBIOLOGY (2018)
Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry
Thomas M. Roston et al.
PLOS ONE (2018)
Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel
Marieke W. Veldkamp et al.
NATURE COMMUNICATIONS (2018)
Caveolin-3 Microdomain: Arrhythmia Implications for Potassium Inward Rectifier and Cardiac Sodium Channel
Ravi Vaidyanathan et al.
FRONTIERS IN PHYSIOLOGY (2018)
Proarrhythmic Remodeling of Calcium Homeostasis in Cardiac Disease; Implications for Diabetes and Obesity
Shanna Hamilton et al.
FRONTIERS IN PHYSIOLOGY (2018)
Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation
Cristina E. Molina et al.
FRONTIERS IN PHYSIOLOGY (2018)
Altered Ca2+ and Na+ Homeostasis in Human Hypertrophic Cardiomyopathy: Implications for Arrhythmogenesis
Raffaele Coppini et al.
FRONTIERS IN PHYSIOLOGY (2018)
Perspectives on the Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Biomedical Research
Christine L. Mummery
STEM CELL REPORTS (2018)
Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking
Ivan Kopljar et al.
STEM CELL REPORTS (2018)
Recent Advances in Short QT Syndrome
Oscar Campuzano et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2018)
Mechanisms Underlying the Actions of Antidepressant and Antipsychotic Drugs That Cause Sudden Cardiac Arrest
Serge Sicouri et al.
ARRHYTHMIA & ELECTROPHYSIOLOGY REVIEW (2018)
Interventricular differences in sodium current and its potential role in Brugada syndrome
Kirstine Calloe et al.
PHYSIOLOGICAL REPORTS (2018)
A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia
Mirko Baruscotti et al.
EUROPEAN HEART JOURNAL (2017)
TREK-1 (K2P2.1) K+ channels are suppressed in patients with atrial fibrillation and heart failure and provide therapeutic targets for rhythm control
Patrick Lugenbiel et al.
BASIC RESEARCH IN CARDIOLOGY (2017)
Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy
Constanze Schmidt et al.
EUROPEAN HEART JOURNAL (2017)
Atrial Fibrillation in Hypertrophic Cardiomyopathy
Kaivan Vaidya et al.
HEART LUNG AND CIRCULATION (2017)
Sick sinus syndrome with HCN4 mutations shows early onset and frequent association with atrial fibrillation and left ventricular noncompaction
Taisuke Ishikawa et al.
HEART RHYTHM (2017)
Subcellular localization of Na/K-ATPase isoforms in ventricular myocytes
Garrick K. Yuen et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
Permissive role of reduced inwardly-rectifying potassium current density in the automaticity of the guinea pig pulmonary vein myocardium
Yayoi Tsuneoka et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2017)
Kir2.1 and K2P1 channels reconstitute two levels of resting membrane potential in cardiomyocytes
Dongchuan Zuo et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Computational analysis of the human sinus node action potential: model development and effects of mutations
Alan Fabbri et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Hypertension-induced remodelling: on the interactions of cardiac risk factors
Jakub Tomek et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics
Nipavan Chiamvimonvat et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Calcium-mediated cellular triggered activity in atrial fibrillation
Dobromir Dobrev et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Quantitative analysis of the Ca2+-dependent regulation of delayed rectifier K+ current IKs in rabbit ventricular myocytes
Daniel C. Bartos et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Knockdown of cardiac Kir3.1 gene with siRNA can improve bradycardia in an experimental sinus bradycardia rat model
Yang Li et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2017)
MECHANISTIC PATHWAYS OF SEX DIFFERENCES IN CARDIOVASCULAR DISEASE
Vera Regitz-Zagrosek et al.
PHYSIOLOGICAL REVIEWS (2017)
MOLECULAR PATHOPHYSIOLOGY OF CONGENITAL LONG QT SYNDROME
M. S. Bohnen et al.
PHYSIOLOGICAL REVIEWS (2017)
MURINE ELECTROPHYSIOLOGICAL MODELS OF CARDIAC ARRHYTHMOGENESIS
Christopher L. -H. Huang
PHYSIOLOGICAL REVIEWS (2017)
Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure
Constanze Schmidt et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2017)
Stretch-activated potassium currents in the heart: Focus on TREK-1 and arrhythmias
Niels Decher et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2017)
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Kasper Thorsen et al.
NATURE COMMUNICATIONS (2017)
A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reconstructions
Michael A. Colman et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Sodium Channel Remodeling in Subcellular Microdomains of Murine Failing Cardiomyocytes
Mathilde R. Rivaud et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
Small-Conductance Calcium-Activated Potassium Current in Normal Rabbit Cardiac Purkinje Cells
Thomas A. Reher et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
Computational Cardiac Modeling Reveals Mechanisms of Ventricular Arrhythmogenesis in Long QT Syndrome Type 8: CACNA1C R858H Mutation Linked to Ventricular Fibrillation
Jieyun Bai et al.
FRONTIERS IN PHYSIOLOGY (2017)
Spatial Patterns of Excitation at Tissue and Whole Organ Level Due to Early Afterdepolarizations
Nele Vandersickel et al.
FRONTIERS IN PHYSIOLOGY (2017)
The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study
Oliver J. Britton et al.
FRONTIERS IN PHYSIOLOGY (2017)
Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment
Sara Dutta et al.
FRONTIERS IN PHYSIOLOGY (2017)
Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity
Elisa Passini et al.
FRONTIERS IN PHYSIOLOGY (2017)
Gating mechanisms underlying deactivation slowing by two KCNQ1 atrial fibrillation mutations
Gary Peng et al.
SCIENTIFIC REPORTS (2017)
Stress-Kinase Regulation of TASK-1 and TASK-3
Susanne Rinne et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Mechanisms of spontaneous pacing: sinoatrial nodal cells, neonatal cardiomyocytes, and human stem cell derived cardiomyocytes
Martin Morad et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2017)
Na+-H+ exchanger and proton channel in heart failure associated with Becker and Duchenne muscular dystrophies
Ghassan Bkaily et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2017)
Atrial-selective K+ channel blockers: potential antiarrhythmic drugs in atrial fibrillation?
Ursula Ravens
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2017)
Activation and Inhibition of Sodium-Hydrogen Exchanger Is a Mechanism That Links the Pathophysiology and Treatment of Diabetes Mellitus With That of Heart Failure
Milton Packer
CIRCULATION (2017)
β-Adrenergic receptor stimulation inhibits proarrhythmic alternans in postinfarction border zone cardiomyocytes: a computational analysis
Jakub Tomek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2017)
Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations
Simona Casini et al.
CARDIOVASCULAR DRUGS AND THERAPY (2017)
Diffuse interstitial fibrosis assessed by cardiac magnetic resonance is associated with dispersion of ventricular repolarization in patients with hypertrophic cardiomyopathy
David Hurtado-de-Mendoza et al.
JOURNAL OF ARRHYTHMIA (2017)
Role of abnormal repolarization in the mechanism of cardiac arrhythmia
O. E. Osadchii
ACTA PHYSIOLOGICA (2017)
Restitution slope is principally determined by steady-state action potential duration
Michael J. Shattock et al.
CARDIOVASCULAR RESEARCH (2017)
The role of spatial organization of Ca2+ release sites in the generation of arrhythmogenic diastolic Ca2+ release in myocytes from failing hearts
Andriy E. Belevych et al.
BASIC RESEARCH IN CARDIOLOGY (2017)
Calcium Signaling Series
David A. Eisner et al.
CIRCULATION RESEARCH (2017)
Local transmural action potential gradients are absent in the isolated, intact dog heart but present in the corresponding coronary-perfused wedge
Bastiaan J. Boukens et al.
PHYSIOLOGICAL REPORTS (2017)
Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes
Yen-Yu Lu et al.
CLINICAL SCIENCE (2017)
Synergistic activation of G protein-gated inwardly rectifying potassium channels by cholesterol and PI(4,5)P2
Anna N. Bukiya et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)
Calcium Signaling and Cardiac Arrhythmias
Andrew P. Landstrom et al.
CIRCULATION RESEARCH (2017)
Electrophysiology of Hypokalemia and Hyperkalemia
James N. Weiss et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2017)
Diagnostic, stratification du risque rythmique et prise en charge du syndrome de Brugada
Jean-Baptiste Gourraud et al.
ARCHIVES OF CARDIOVASCULAR DISEASES (2017)
Sodium permeable and hypersensitive TREK-1 channels cause ventricular tachycardia
Niels Decher et al.
EMBO MOLECULAR MEDICINE (2017)
Dynamical mechanisms of phase-2 early afterdepolarizations in human ventricular myocytes: insights from bifurcation analyses of two mathematical models
Yasutaka Kurata et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2017)
Improving the In Silico Assessment of Proarrhythmia Risk by Combining hERG (Human Ether-a-go-go-Related Gene) Channel-Drug Binding Kinetics and Multichannel Pharmacology
Zhihua Li et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2017)
In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes
Xin Zhou et al.
CIRCULATION RESEARCH (2016)
Drug-induced proarrhythmia: risk factors and electrophysiological mechanisms
Gerrit Frommeyer et al.
NATURE REVIEWS CARDIOLOGY (2016)
Myocyte repolarization modulates myocardial function in aging dogs
Andrea Sorrentino et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2016)
A technical review of optical mapping of intracellular calcium within myocardial tissue
Rafael Jaimes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2016)
Cardiac sympatho-vagal balance and ventricular arrhythmia
Manish Kalla et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2016)
Enhancement of Automaticity by Mechanical Stretch of the Isolated Guinea Pig Pulmonary Vein Myocardium
Shogo Hamaguchi et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2016)
A Dynamical Threshold for Cardiac Delayed Afterdepolarization-Mediated Triggered Activity
Michael B. Liu et al.
BIOPHYSICAL JOURNAL (2016)
The novel late Na+ current inhibitor, GS-6615 (eleclazine) and its anti-arrhythmic effects in rabbit isolated heart preparations
Sridharan Rajamani et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene
Peter Major et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Sex Differences in the Biology and Pathology of the Aging Heart
Kaitlyn M. Keller et al.
CANADIAN JOURNAL OF CARDIOLOGY (2016)
Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction
Esma N. Okatan et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2016)
Short QT Syndrome in Current Clinical Practice
Sahil Khera et al.
CARDIOLOGY IN REVIEW (2016)
Atrial Fibrillation-Mediated Upregulation of miR-30d Regulates Myocardial Electrical Remodeling of the G-Protein-Gated K+ Channel, IK.ACh
Masaki Morishima et al.
CIRCULATION JOURNAL (2016)
Histological and Histometric Characterization of Myocardial Fibrosis in End-Stage Hypertrophic Cardiomyopathy: A Clinical-Pathological Study of 30 Explanted Hearts
Giuseppe Galati et al.
CIRCULATION-HEART FAILURE (2016)
Latrunculin B modulates electrophysiological characteristics and arrhythmogenesis in pulmonary vein cardiomyocytes
Yen-Yu Lu et al.
CLINICAL SCIENCE (2016)
Role of CaMKII and PKA in Early Afterdepolarization of Human Ventricular Myocardium Cell: A Computational Model Study
Ling Dai et al.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2016)
Brugada Syndrome: Clinical, Genetic, Molecular, Cellular, and Ionic Aspects
Charles Antzelevitch et al.
CURRENT PROBLEMS IN CARDIOLOGY (2016)
Electrolyte disturbances differentially regulate sinoatrial node and pulmonary vein electrical activity: A contribution to hypokalemia- or hyponatremia-induced atrial fibrillation
Yen-Yu Lu et al.
HEART RHYTHM (2016)
Carnitine deficiency induces a short QT syndrome
Julien Roussel et al.
HEART RHYTHM (2016)
Renal failure induces atrial arrhythmogenesis from discrepant electrophysiological remodeling and calcium regulation in pulmonary veins, sinoatrial node, and atria
Shih-Yu Huang et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)
Remodeling of the intercalated disc related to aging in the mouse heart
Tomasz A. Bonda et al.
JOURNAL OF CARDIOLOGY (2016)
Sex-related differences in age-associated downregulation of human ventricular myocardial β1-adrenergic receptors
JoAnn Lindenfeld et al.
JOURNAL OF HEART AND LUNG TRANSPLANTATION (2016)
Current controversies in determining the main mechanisms of atrial fibrillation
U. Schotten et al.
JOURNAL OF INTERNAL MEDICINE (2016)
Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If funny current
Mirko Baruscotti et al.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2016)
The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size
Alex Horby Christensen et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Characterization and influence of cardiac background sodium current in the atrioventricular node
Hongwei Cheng et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Sarcolemmal Ca2+-entry through L-type Ca2+ channels controls the profile of Ca2+-activated Cl- current in canine ventricular myocytes
Balks Horvath et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift
Hitoshi Uchinoumi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
Ross H. Johnstone et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy
Elisa Passini et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes
Stefano Morotti et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Perpetuation of torsade de pointes in heterogeneous hearts: competing foci or re-entry?
Nele Vandersickel et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
The agonist-specific voltage dependence of M2 muscarinic receptors modulates the deactivation of the acetylcholine-gated K+ current (I KACh)
Eloy G. Moreno-Galindo et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Anti-arrhythmic strategies for atrial fibrillation The role of computational modeling in discovery, development, and optimization
Eleonora Grandi et al.
PHARMACOLOGY & THERAPEUTICS (2016)
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments
Zsofia Kohajda et al.
PLOS ONE (2016)
Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition
E. Pueyo et al.
PLOS ONE (2016)
Early afterdepolarizations promote transmural reentry in ischemic human ventricles with reduced repolarization reserve
Sara Dutta et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2016)
Dispersion in ventricular repolarization in the human, canine and porcine heart
Tobias Opthof et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2016)
Variability in cardiac electrophysiology: Using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm
Anna Muszkiewicz et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2016)
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase
Svetlana N. Reilly et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc
Alejandra Leo-Macias et al.
NATURE COMMUNICATIONS (2016)
Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes
Shih-Yu Huang et al.
ONCOTARGET (2016)
A unified theory of calcium alternans in ventricular myocytes
Zhilin Qu et al.
SCIENTIFIC REPORTS (2016)
Molecular and Electrophysiological Mechanisms Underlying Cardiac Arrhythmogenesis in Diabetes Mellitus
Gary Tse et al.
JOURNAL OF DIABETES RESEARCH (2016)
A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity
Andrew P. Holmes et al.
PLOS ONE (2016)
Spatial Heterogeneity of Cx43 is an Arrhythmogenic Substrate of Polymorphic Ventricular Tachycardias during Compensated Cardiac Hypertrophy in Rats
Mohamed Boulaksil et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2016)
Atrial Electrophysiological Remodeling and Fibrillation in Heart Failure
Sandeep V. Pandit et al.
CLINICAL MEDICINE INSIGHTS-CARDIOLOGY (2016)
Multiple ion channel block by the cation channel inhibitor SKF-96365 in myocytes from the rabbit atrioventricular node
Hongwei Cheng et al.
PHYSIOLOGICAL REPORTS (2016)
Interaction of DPP10a with Kv4.3 channel complex results in a sustained current component of human transient outward current Ito
K. Turnow et al.
BASIC RESEARCH IN CARDIOLOGY (2015)
Calcium-Voltage Coupling in the Genesis of Early and Delayed Afterdepolarizations in Cardiac Myocytes
Zhen Song et al.
BIOPHYSICAL JOURNAL (2015)
Na+-H+ exchanger inhibitor prevents early death in hereditary cardiomyopathy
Ghassan Bkaily et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2015)
A new KCNQ1 mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome
Cristina Moreno et al.
CARDIOVASCULAR RESEARCH (2015)
Altered Myocardial Calcium Cycling and Energetics in Heart Failure-A Rational Approach for Disease Treatment
Przemek A. Gorski et al.
CELL METABOLISM (2015)
Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation
Constanze Schmidt et al.
CIRCULATION (2015)
Role of Inflammation in Atrial Fibrillation Pathophysiology and Management
Masahide Harada et al.
CIRCULATION JOURNAL (2015)
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Insights Into Molecular, Cellular, and Functional Phenotypes
Ioannis Karakikes et al.
CIRCULATION RESEARCH (2015)
Loss-of-Function SCN5A Mutations Associated With Sinus Node Dysfunction, Atrial Arrhythmias, and Poor Pacemaker Capture
David Y. Chiang et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2015)
Traditional vs. genetic pathogenesis of arrhythmogenic right ventricular cardiomyopathy
Dongdong Que et al.
EUROPACE (2015)
Delayed afterdepolarizations generate both triggers and a vulnerable substrate promoting reentry in cardiac tissue
Michael B. Liu et al.
HEART RHYTHM (2015)
Synergistic antiarrhythmic effect of combining inhibition of Ca2+-activated K+ (SK) channels and voltage-gated Na+ channels in an isolated heart model of atrial fibrillation
Jeppe Egedal Kirchhoff et al.
HEART RHYTHM (2015)
Selective and non-selective non-steroidal anti-inflammatory drugs differentially regulate pulmonary vein and atrial arrhythmogenesis
Chien-Jung Chang et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)
Down-regulation of the Small Conductance Calcium-activated Potassium Channels in Diabetic Mouse Atria
Fu Yi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
IKs Gain- and Loss-of-Function in Early-Onset Lone Atrial Fibrillation
Annette Buur Steffensen et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2015)
Oxidant and Inflammatory Mechanisms and Targeted Therapy in Atrial Fibrillation: An Update
Alejandra Gutierrez et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2015)
Oxidant stress promotes disease by activating CaMKII
Mark E. Anderson
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Thyroid stimulating hormone directly modulates cardiac electrical activity
H. Alonso et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes
Susanne Rinne et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Perspective: A dynamics-based classification of ventricular arrhythmias
James N. Weiss et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization
Jonathan M. Cordeiro et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
T-tubule disruption promotes calcium alternans in failing ventricular myocytes: Mechanistic insights from computational modeling
Michael Nival et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Sick sinus syndrome and atrial fibrillation in older persons - A view from the sinoatrial nodal myocyte
O. Monfredi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Na+/Ca2+ exchange and Na+/K+-ATPase in the heart
Michael J. Shattock et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Heart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling
Victor P. Long et al.
LIFE SCIENCES (2015)
Late Na+ current and protracted electrical recovery are critical determinants of the aging myopathy
Sergio Signore et al.
NATURE COMMUNICATIONS (2015)
Cell-Specific Cardiac Electrophysiology Models
Willemijn Groenendaal et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome
Alfonso Bueno-Orovio et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Functional role of voltage gated Ca2+ channels in heart automaticity
Pietro Mesirca et al.
FRONTIERS IN PHYSIOLOGY (2015)
Cytosolic calcium ions exert a major influence on the firing rate and maintenance of pacemaker activity in guinea-pig sinus node
Rebecca A. Capel et al.
FRONTIERS IN PHYSIOLOGY (2015)
The importance of Ca2+-dependent mechanisms for the initiation of the heartbeat
Rebecca A. Capel et al.
FRONTIERS IN PHYSIOLOGY (2015)
From two competing oscillators to one coupled-clock pacemaker cell system
Yael Yaniv et al.
FRONTIERS IN PHYSIOLOGY (2015)
The Uremic Toxin Indoxyl Sulfate Increases Pulmonary Vein and Atrial Arrhythmogenesis
Wei-Ta Chen et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2015)
Contribution of sodium channel neuronal isoform Na(v)1.1 to late sodium current in ventricular myocytes from failing hearts
Sudhish Mishra et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
The potassium current carried by TREK-1 channels in rat cardiac ventricular muscle
Mandy Bodnar et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation
Claire Poulet et al.
PLOS ONE (2015)
Ion Channels in the Heart
Daniel C. Bartos et al.
COMPREHENSIVE PHYSIOLOGY (2015)
The Role of Dyadic Organization in Regulation of Sarcoplasmic Reticulum Ca2+ Handling during Rest in Rabbit Ventricular Myocytes
Elisa Bovo et al.
BIOPHYSICAL JOURNAL (2014)
Selective Na+/Ca2+ exchanger inhibition prevents Ca2+ overload-induced triggered arrhythmias
Norbert Nagy et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice
Ming-Ming Wu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization
Bo Liang et al.
CARDIOVASCULAR RESEARCH (2014)
SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation
Eleonora Savio-Galimberti et al.
CARDIOVASCULAR RESEARCH (2014)
Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria
Lasse Skibsbye et al.
CARDIOVASCULAR RESEARCH (2014)
Dominant Frequency Increase Rate Predicts Transition from Paroxysmal to Long-Term Persistent Atrial Fibrillation
Raphael P. Martins et al.
CIRCULATION (2014)
Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog
Xiao-Yan Qi et al.
CIRCULATION (2014)
Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression
Jordi Heijman et al.
CIRCULATION RESEARCH (2014)
Electrocardiographic T Wave and its Relation With Ventricular Repolarization Along Major Anatomical Axes
Veronique M. F. Meijborg et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2014)
Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder
Corinna Friedrich et al.
EMBO MOLECULAR MEDICINE (2014)
Inhibition of cardiac two-pore-domain K+ (K2p) channels - an emerging antiarrhythmic concept
Constanze Schmidt et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
How do sex hormones modify arrhythmogenesis in Long QT syndrome? Sex hormone effects on arrhythmogenic substrate and triggered activity
Katja E. Odening et al.
HEART RHYTHM (2014)
Distinctive electrophysiological characteristics of right ventricular out-flow tract cardiomyocytes
Yen-Yu Lu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2014)
In vivo recording of Zhang's phenomenon (His electrogram alternans): a novel index of atrioventricular node dual pathway conduction
Youhua Zhang
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2014)
Pathological impact of hyperpolarization-activated chloride current peculiar to rat pulmonary vein cardiomyocytes
Yosuke Okamoto et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Cardiac fibrosis and arrhythmogenesis: The road to repair is paved with perils
Thao P. Nguyen et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Detailed characterization of microRNA changes in a canine heart failure model: Relationship to arrhythmogenic structural remodeling
Yu Chen et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Misinterpretation of the mouse ECG: 'musing the waves of Mus musculus'
Bastiaan J. Boukens et al.
JOURNAL OF PHYSIOLOGY-LONDON (2014)
A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII
S. Morotti et al.
JOURNAL OF PHYSIOLOGY-LONDON (2014)
Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization
Alfonso Bueno-Orovio et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2014)
β1-adrenergic regulation of rapid component of delayed rectifier K+ currents in guinea-pig cardiac myocytes
Sen Wang et al.
MOLECULAR MEDICINE REPORTS (2014)
Cardiac expression and atrial fibrillation-associated remodeling of K2p2.1 (TREK-1) K+ channels in a porcine model
Constanze Schmidt et al.
LIFE SCIENCES (2014)
CARDIAC POTASSIUM CHANNEL SUBTYPES: NEW ROLES IN REPOLARIZATION AND ARRHYTHMIA
Nicole Schmitt et al.
PHYSIOLOGICAL REVIEWS (2014)
L-TYPE CaV1.2 CALCIUM CHANNELS: FROM IN VITRO FINDINGS TO IN VIVO FUNCTION
Franz Hofmann et al.
PHYSIOLOGICAL REVIEWS (2014)
Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+ and Ca2+ and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes
Erkan Tuncay et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
The Role of Purkinje-Myocardial Coupling during Ventricular Arrhythmia: A Modeling Study
Elham Behradfar et al.
PLOS ONE (2014)
Beat-to-Beat Cycle Length Variability of Spontaneously Beating Guinea Pig Sinoatrial Cells: Relative Contributions of the Membrane and Calcium Clocks
Massimiliano Zaniboni et al.
PLOS ONE (2014)
Na/K pump regulation of cardiac repolarization: insights from a systems biology approach
Alfonso Bueno-Orovio et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation
Chang-Seok Ki et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
Inter-Subject Variability in Human Atrial Action Potential in Sinus Rhythm versus Chronic Atrial Fibrillation
Carlos Sanchez et al.
PLOS ONE (2014)
Calcium-Activated Potassium Current Modulates Ventricular Repolarization in Chronic Heart Failure
Ingrid M. Bonilla et al.
PLOS ONE (2014)
hERG 1b is critical for human cardiac repolarization
David K. Jones et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Altered and dynamic ion selectivity of K+ channels in cell development and excitability
Haijun Chen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Exercise training reduces resting heart rate via downregulation of the funny channel HCN4
Alicia D'Souza et al.
NATURE COMMUNICATIONS (2014)
Regulation of the NaV1.5 cytoplasmic domain by calmodulin
Sandra B. Gabelli et al.
NATURE COMMUNICATIONS (2014)
Structural analyses of Ca2+/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation
Chaojian Wang et al.
NATURE COMMUNICATIONS (2014)
Ca2+ current facilitation is CaMKII-dependent and has arrhythmogenic consequences
Donald M. Bers et al.
FRONTIERS IN PHARMACOLOGY (2014)
Passive ventricular remodeling in cardiac disease: focus on heterogeneity
Elise L. Kessler et al.
FRONTIERS IN PHYSIOLOGY (2014)
β-adrenergic receptor responsiveness in aging heart and clinical implications
Nicola Ferrara et al.
FRONTIERS IN PHYSIOLOGY (2014)
Computational Models of Ventricular- and Atrial-Like Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Michelangelo Paci et al.
ANNALS OF BIOMEDICAL ENGINEERING (2013)
ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart
N. Jost et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias
Carol Ann Remme et al.
CARDIOVASCULAR DRUGS AND THERAPY (2013)
Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue
Hiroki Takanari et al.
CARDIOVASCULAR RESEARCH (2013)
The topology of the C-terminal sections of the NCX1 Na+/Ca2+ exchanger and the NCKX2 Na+/Ca2+-K+ exchanger
Robert T. Szerencsei et al.
CHANNELS (2013)
Upregulation of the Hyperpolarization-Activated Current Increases Pacemaker Activity of the Sinoatrial Node and Heart Rate During Pregnancy in Mice
Nabil El Khoury et al.
CIRCULATION (2013)
Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy
Raffaele Coppini et al.
CIRCULATION (2013)
Mechanisms of Altered Ca2+ Handling in Heart Failure
Min Luo et al.
CIRCULATION RESEARCH (2013)
Diastolic Spontaneous Calcium Release From the Sarcoplasmic Reticulum Increases Beat-to-Beat Variability of Repolarization in Canine Ventricular Myocytes After β-Adrenergic Stimulation
Daniel M. Johnson et al.
CIRCULATION RESEARCH (2013)
Executive summary: HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes
Silvia G. Priori et al.
EUROPACE (2013)
The mechanical uncoupler blebbistatin is associated with significant electrophysiological effects in the isolated rabbit heart
Kieran E. Brack et al.
EXPERIMENTAL PHYSIOLOGY (2013)
Connexins and the atrioventricular node
Ian P. Temple et al.
HEART RHYTHM (2013)
Distinctive sodium and calcium regulation associated with sex differences in atrial electrophysiology of rabbits
Wen-Chin Tsai et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
The onset mechanisms of ventricular tachycardia
Taner Ulus et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
Chronic Atrial Fibrillation Alters the Functional Properties of If in the Human Atrium
Francesca Stillitano et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2013)
A KCNQ1 Mutation Causes a High Penetrance for Familial Atrial Fibrillation
Daniel C. Bartos et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2013)
Human Electrophysiological and Pharmacological Properties of XEN-D0101: A Novel Atrial-Selective Kv1.5/IKur Inhibitor
John Ford et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2013)
The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation
Pietro Mesirca et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations
Jose M. Di Diego et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
H+-activated Na+ influx in the ventricular myocyte couples Ca2+-signalling to intracellular pH
Carolina D. Garciarena et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
The topology of the cardiac Na+/Ca2+ exchanger, NCX1
Xiaoyan Ren et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Ca2+ channel and Na+/Ca2+ exchange localization in cardiac myocytes
David R. L. Scriven et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Novel regulation of cardiac Na pump via phospholemman
Davor Pavlovic et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Regulation of the cardiac Na+/H+ exchanger in health and disease
Shigeo Wakabayashi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Structural and functional insights into the cardiac Na+/H+ exchanger
Brian L. Lee et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Dynamics of the late Na+ current during cardiac action potential and its contribution to afterdepolarizations
Balazs Horvath et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
The emergence of subcellular pacemaker sites for calcium waves and oscillations
Michael Nivala et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Funny channel gene mutations associated with arrhythmias
Dario DiFrancesco
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Voltage sensitivity of M2 muscarinic receptors underlies the delayed rectifier-like activation of ACh-gated K+ current by choline in feline atrial myocytes
Ricardo A. Navarro-Polanco et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs
Norbert Jost et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Atrial selectivity of antiarrhythmic drugs
Ursula Ravens et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
The SLC8 gene family of sodium-calcium exchangers (NCX) - Structure, function, and regulation in health and disease
Daniel Khananshvili
MOLECULAR ASPECTS OF MEDICINE (2013)
Type II diabetes promotes a myofibroblast phenotype in cardiac fibroblasts
Vennece Fowlkes et al.
LIFE SCIENCES (2013)
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
Connie R. Bezzina et al.
NATURE GENETICS (2013)
Formation of Spatially Discordant Alternans Due to Fluctuations and Diffusion of Calcium
Daisuke Sato et al.
PLOS ONE (2013)
[Ca2+]i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium
Norbert Nagy et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2013)
Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology
Oliver J. Britton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate
Eric D. Larson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Myocardial expression of hyperpolarization-activated, cyclic nucleotide-gated proteins in healthy cats and cats with hypertrophic cardiomyopathy
S. C. Riesen et al.
SCHWEIZER ARCHIV FUR TIERHEILKUNDE (2013)
Calcium Transient and Sodium-Calcium Exchange Current in Human versus Rabbit Sinoatrial Node Pacemaker Cells
Arie O. Verkerk et al.
SCIENTIFIC WORLD JOURNAL (2013)
Functional, Anatomical, and Molecular Investigation of the Cardiac Conduction System and Arrhythmogenic Atrioventricular Ring Tissue in the Rat Heart
Andrew J. Atkinson et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
Heterogeneous Upregulation of Apamin-Sensitive Potassium Currents in Failing Human Ventricles
Po-Cheng Chang et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
Benchmarking electrophysiological models of human atrial myocytes
Mathias Wilhelms et al.
FRONTIERS IN PHYSIOLOGY (2013)
Phenomics of Cardiac Chloride Channels
Dayue Darrel Duan
COMPREHENSIVE PHYSIOLOGY (2013)
Defective calcium inactivation causes long QT in obese insulin-resistant rat
Yen-Chang Lin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Bridging experiments, models and simulations: an integrative approach to validation in computational cardiac electrophysiology
Annamaria Carusi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents?
Zhenghang Zhao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation
Morten S. Olesen et al.
BMC MEDICAL GENETICS (2012)
Biology of cardiac sodium channel Na(v)1.5 expression
Martin B. Rook et al.
CARDIOVASCULAR RESEARCH (2012)
Na+/K+-ATPase α2-isoform preferentially modulates Ca2+ transients and sarcoplasmic reticulum Ca2+ release in cardiac myocytes
Sanda Despa et al.
CARDIOVASCULAR RESEARCH (2012)
TREK-1 K+ Channels in the Cardiovascular System: Their Significance and Potential as a Therapeutic Target
Lakshman Goonetilleke et al.
CARDIOVASCULAR THERAPEUTICS (2012)
Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation
Niels Voigt et al.
CIRCULATION (2012)
High-Resolution 3-Dimensional Reconstruction of the Infarct Border Zone Impact of Structural Remodeling on Electrical Activation
Sally L. Rutherford et al.
CIRCULATION RESEARCH (2012)
Functional NaV1.8 Channels in Intracardiac Neurons The Link Between SCN10A and Cardiac Electrophysiology
Arie O. Verkerk et al.
CIRCULATION RESEARCH (2012)
Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium
Yung-Kuo Lin et al.
CLINICAL SCIENCE (2012)
Mechanisms of Arrhythmias and Conduction Disorders in Older Adults
Mahek Mirza et al.
CLINICS IN GERIATRIC MEDICINE (2012)
A KCNJ8 mutation associated with early repolarization and atrial fibrillation
Jessica T. Delaney et al.
EUROPACE (2012)
Profile of L-type Ca2+ current and Na+/Ca2+ exchange current during cardiac action potential in ventricular myocytes
Tamas Banyasz et al.
HEART RHYTHM (2012)
Estradiol promotes sudden cardiac death in transgenic long QT type 2 rabbits while progesterone is protective
Katja E. Odening et al.
HEART RHYTHM (2012)
Beat-to-beat variability of repolarization as a new biomarker for proarrhythmia in vivo
Rosanne Varkevisser et al.
HEART RHYTHM (2012)
Rebuttal: The funny current in the context of the coupled clock pacemaker cell system
Dario DiFrancesco et al.
HEART RHYTHM (2012)
Is sodium current present in human sinoatrial node cells?
Arie O. Verkerk et al.
International Journal of Biological Sciences (2012)
Acid-sensitive TWIK and TASK Two-pore Domain Potassium Channels Change Ion Selectivity and Become Permeable to Sodium in Extracellular Acidification
Liqun Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Augmentation of Kv4.2-encoded Currents by Accessory Dipeptidyl Peptidase 6 and 10 Subunits Reflects Selective Cell Surface Kv4.2 Protein Stabilization
Nicholas C. Foeger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The A-kinase Anchoring Protein Yotiao Facilitates Complex Formation between Adenylyl Cyclase Type 9 and the IKs Potassium Channel in Heart
Yong Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice
Alexander Froese et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
About half of the late sodium current in cardiac myocytes from dog ventricle is due to non-cardiac-type Na+ channels
Michael Biet et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Exploiting mathematical models to illuminate electrophysiological variability between individuals
Amrita X. Sarkar et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Theoretical study of L-type Ca2+ current inactivation kinetics during action potential repolarization and early afterdepolarizations
Stefano Morotti et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Oestrogen upregulates L-type Ca2+ channels via oestrogen-receptor-α by a regional genomic mechanism in female rabbit hearts
Xiaoyan Yang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation
Stefano Severi et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
hERG K+ CHANNELS: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE
Jamie I. Vandenberg et al.
PHYSIOLOGICAL REVIEWS (2012)
Long-Chain Acylcarnitines Regulate the hERG Channel
Fabio Ferro et al.
PLOS ONE (2012)
In Vivo Human Left-to-Right Ventricular Differences in Rate Adaptation Transiently Increase Pro-Arrhythmic Risk following Rate Acceleration
Alfonso Bueno-Orovio et al.
PLOS ONE (2012)
Repolarization gradients in the intact heart: Transmural or apico-basal?
Michiel J. Janse et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2012)
Computational modeling and numerical methods for spatiotemporal calcium cycling in ventricular myocytes
Michael Nivala et al.
FRONTIERS IN PHYSIOLOGY (2012)
Carbonylation Induces Heterogeneity in Cardiac Ryanodine Receptor Function in Diabetes Mellitus
Chun Hong Shao et al.
MOLECULAR PHARMACOLOGY (2012)
Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/reperfusion injury
Sunny Yang Xiang et al.
ACTA PHARMACOLOGICA SINICA (2011)
The ClC-3 chloride channels in cardiovascular disease
Dayue Darrel Duan
ACTA PHARMACOLOGICA SINICA (2011)
Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers
Alberto Corrias et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Discrepant electrophysiological characteristics and calcium homeostasis of left atrial anterior and posterior myocytes
Kazuyoshi Suenari et al.
BASIC RESEARCH IN CARDIOLOGY (2011)
Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform
C. Y. Du et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
A Multiscale Investigation of Repolarization Variability and Its Role in Cardiac Arrhythmogenesis
Esther Pueyo et al.
BIOPHYSICAL JOURNAL (2011)
Analysis of the contribution of Ito to repolarization in canine ventricular myocardium
L. Virag et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Cardiac ventricular repolarization reserve: a principle for understanding drug-related proarrhythmic risk
Andras Varro et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Expression of hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN4) is increased in hypertrophic cardiomyopathy
Huang Wei-qing et al.
CARDIOVASCULAR PATHOLOGY (2011)
TASK-1 Channels May Modulate Action Potential Duration of Human Atrial Cardiomyocytes
Sven H. Limberg et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)
Repolarization Alternans Reveals Vulnerability to Human Atrial Fibrillation
Sanjiv M. Narayan et al.
CIRCULATION (2011)
Whole-Heart Modeling Applications to Cardiac Electrophysiology and Electromechanics
Natalia A. Trayanova
CIRCULATION RESEARCH (2011)
Human Atrial Action Potential and Ca2+ Model Sinus Rhythm and Chronic Atrial Fibrillation
Eleonora Grandi et al.
CIRCULATION RESEARCH (2011)
Alternans and Arrhythmias From Cell to Heart
James N. Weiss et al.
CIRCULATION RESEARCH (2011)
Characterization of Gap Junction Remodeling in Epicardial Border Zone of Healing Canine Infarcts and Electrophysiological Effects of Partial Reversal by Rotigaptide
Ester Macia et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2011)
Sex Differences in the Electrophysiological Characteristics of Pulmonary Veins and Left Atrium and Their Clinical Implication in Atrial Fibrillation
Wen-Chin Tsai et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2011)
Heart failure enhances arrhythmogenesis in pulmonary veins
Shih-Lin Chang et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2011)
Role of Ca2+-Sensitive K+ Currents in Controlling Ventricular Repolarization: Possible Implications for Future Antiarrhytmic Drug Therapy
N. Nagy et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Sarcolemmal KATP Channel Modulators and Cardiac Arrhythmias
I. Baczko et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Powerful Technique to Test Selectivity of Agents Acting on Cardiac Ion Channels: The Action Potential Voltage-Clamp
N. Szentandrassy et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)
Christian Templin et al.
EUROPEAN HEART JOURNAL (2011)
Ageing-dependent remodelling of ion channel and Ca2+ clock genes underlying sino-atrial node pacemaking
James O. Tellez et al.
EXPERIMENTAL PHYSIOLOGY (2011)
Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart
F. C. Howarth et al.
EXPERIMENTAL PHYSIOLOGY (2011)
Left ventricle structural remodelling in the prediabetic Goto-Kakizaki rat
Alicia D'Souza et al.
EXPERIMENTAL PHYSIOLOGY (2011)
Long-term clinical outcome of extensive pulmonary vein isolation-based catheter ablation therapy in patients with paroxysmal and persistent atrial fibrillation
Shinsuke Miyazaki et al.
HEART (2011)
Successes and failures in modeling heart cell electrophysiology
Denis Noble
HEART RHYTHM (2011)
Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes
Xianming Lin et al.
HEART RHYTHM (2011)
Refining repolarization reserve
Dan M. Roden et al.
HEART RHYTHM (2011)
R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation
Daniel C. Bartos et al.
HEART RHYTHM (2011)
Structure of Human Na+/H+ Exchanger NHE1 Regulatory Region in Complex with Calmodulin and Ca2+
Stefan Koester et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Antiarrhythmic Effects of Losartan and Enalapril in Canine Pulmonary Vein Sleeve Preparations
Serge Sicouri et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2011)
Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes
Kirstine Calloe et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2011)
hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: A possible mechanism for long QT syndrome
Matthew C. Trudeau et al.
JOURNAL OF GENERAL PHYSIOLOGY (2011)
CaMKII in myocardial hypertrophy and heart failure
Mark E. Anderson et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Sequential dissection of multiple ionic currents in single cardiac myocytes under action potential-clamp
Tamas Banyasz et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient
Jordi Heijman et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Microdomain [Ca2+] near ryanodine receptors as reported by L-type Ca2+and Na+/Ca2+exchange currents
Karoly Acsai et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Regional genomic regulation of cardiac sodium-calcium exchanger by oestrogen
Guojun Chen et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Long-Term Follow-Up of Patients With Short QT Syndrome
Carla Giustetto et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)
2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Bernard J. Gersh et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)
Pathophysiological Mechanisms of Atrial Fibrillation: A Translational Appraisal
Ulrich Schotten et al.
PHYSIOLOGICAL REVIEWS (2011)
Increased Short-Term Variability of the QT Interval in Professional Soccer Players: Possible Implications for Arrhythmia Prediction
Csaba Lengyel et al.
PLOS ONE (2011)
Bisphenol A and 17β-Estradiol Promote Arrhythmia in the Female Heart via Alteration of Calcium Handling
Sujuan Yan et al.
PLOS ONE (2011)
Voltage-dependent potassium currents in feline sino-atrial node myocytes
Ivan A. Arechiga-Figueroa et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2011)
A human ventricular cell model for investigation of cardiac arrhythmias under hyperkalaemic conditions
Jesus Carro et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2011)
Is the 'Athlete's Heart' Arrhythmogenic? Implications for Sudden Cardiac Death
Thomas Rowland
SPORTS MEDICINE (2011)
Coupled personalization of cardiac electrophysiology models for prediction of ischaemic ventricular tachycardia
Jatin Relan et al.
INTERFACE FOCUS (2011)
Impact of Sarcoplasmic Reticulum Calcium Release on Calcium Dynamics and Action Potential Morphology in Human Atrial Myocytes: A Computational Study
Jussi T. Koivumaki et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation
Thomas O'Hara et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Predictive value of electrical restitution in hypokalemia-induced ventricular arrhythmogenicity
Oleg E. Osadchii et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Ionic mechanisms of electrophysiological heterogeneity and conduction block in the infarct border zone
Keith F. Decker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Reduced expression of the Na+/Ca2+ exchanger in adult cardiomyocytes via adenovirally delivered shRNA results in resistance to simulated ischemic injury
Thane G. Maddaford et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Simulations of Reduced Conduction Reserve in the Diabetic Rat Heart: Response to Uncoupling and Reduced Excitability
Haisam A. Ghaly et al.
ANNALS OF BIOMEDICAL ENGINEERING (2010)
So Little Source, So Much Sink: Requirements for Afterdepolarizations to Propagate in Tissue
Yuanfang Xie et al.
BIOPHYSICAL JOURNAL (2010)
Ryanodine Receptor Phosphorylation by Calcium/Calmodulin-Dependent Protein Kinase II Promotes Life-Threatening Ventricular Arrhythmias in Mice With Heart Failure
Ralph J. van Oort et al.
CIRCULATION (2010)
Sudden Cardiac Death Prediction and Prevention Report From a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop
Glenn I. Fishman et al.
CIRCULATION (2010)
Abnormal Action Potential Duration Restitution Property in the Right Ventricular Outflow Tract in Brugada Syndrome
Sonoko Ashino et al.
CIRCULATION JOURNAL (2010)
Increased Coupled Gating of L-Type Ca2+ Channels During Hypertension and Timothy Syndrome
Manuel F. Navedo et al.
CIRCULATION RESEARCH (2010)
The Role of the Funny Current in Pacemaker Activity
Dario DiFrancesco
CIRCULATION RESEARCH (2010)
Early Repolarization Associated With Ventricular Arrhythmias in Patients With Chronic Coronary Artery Disease
Ravi B. Patel et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2010)
Mechanisms of hypokalemia-induced ventricular arrhythmogenicity
Oleg E. Osadchii
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2010)
Cellular basis for atrial fibrillation in an experimental model of short QT1: Implications for a pharmacological approach to therapy
Eyal Nof et al.
HEART RHYTHM (2010)
Early afterdepolarizations and cardiac arrhythmias
James N. Weiss et al.
HEART RHYTHM (2010)
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing
Jamie D. Kapplinger et al.
HEART RHYTHM (2010)
Transseptal Dispersion of Repolarization and Its Role in the Development of Torsade de Pointes Arrhythmias
Serge Sicouri et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2010)
Activation of the cardiac Na+-Ca2+ exchanger by sorcin via the interaction of the respective Ca2+-binding domains
Carlotta Zamparelli et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts
Nathalie Gaborit et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Control of the cardiac action potential: The role of repolarization dynamics
Antonio Zaza
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
A novel computational model of the human ventricular action potential and Ca transient
Eleonora Grandi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Optical mapping study of blebbistatin-induced chaotic electrical activities in isolated rat atrium preparations
Natnicha Kanlop et al.
JOURNAL OF PHYSIOLOGICAL SCIENCES (2010)
A computational model of Purkinje fibre single cell electrophysiology: implications for the long QT syndrome
K. J. Sampson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
In Humans, Chronic Atrial Fibrillation Decreases the Transient Outward Current and Ultrarapid Component of the Delayed Rectifier Current Differentially on Each Atria and Increases the Slow Component of the Delayed Rectifier Current in Both
Ricardo Caballero et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)
Genetic variation in SCN10A influences cardiac conduction
John C. Chambers et al.
NATURE GENETICS (2010)
The beta Subunit of Voltage-Gated Ca2+ Channels
Zafir Buraei et al.
PHYSIOLOGICAL REVIEWS (2010)
Possible mechanisms of sudden cardiac death in top athletes: a basic cardiac electrophysiological point of view
Andras Varro et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
Testosterone-augmented contractile responses to α1- and β1- adrenoceptor stimulation are associated with increased activities of RyR, SERCA, and NCX in the heart
Sharon Tsang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)
Sex-dependent impairment of cardiac action potential conduction in type 1 diabetic rats
Yakhin Shimoni et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Stretch-activated channel activation promotes early afterdepolarizations in rat ventricular myocytes under oxidative stress
Yanggan Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium
Keith F. Decker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Functional properties of murine bestrophin 1 channel
Kate E. O'Driscoll et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing
Qiuju Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Self-augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency
Laszlo Virag et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Larger dispersion of INa in female dog ventricle as a mechanism for gender-specific incidence of cardiac arrhythmias
Hector Barajas-Martinez et al.
CARDIOVASCULAR RESEARCH (2009)
Reverse rate dependency is an intrinsic property of canine cardiac preparations
Tamas Banyasz et al.
CARDIOVASCULAR RESEARCH (2009)
Spatiotemporal intracellular calcium dynamics during cardiac alternans
Juan G. Restrepo et al.
CHAOS (2009)
Systematic Assessment of Patients With Unexplained Cardiac Arrest Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER)
Andrew D. Krahn et al.
CIRCULATION (2009)
Ion Channel Transcript Expression at the Rabbit Atrioventricular Conduction Axis
Ian D. Greener et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2009)
Two-pore potassium channels in the cardiovascular system
Alison Gurney et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2009)
Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases
Nathalie Gaborit et al.
EUROPEAN HEART JOURNAL (2009)
Rapid component IKr of cardiac delayed rectifier potassium currents in guinea-pig is inhibited by α1-adrenoreceptor activation via protein kinase A and protein kinase C-dependent pathways
Sen Wang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Dispersion of repolarization and arrhythmogenesis
Ruben Coronel et al.
HEART RHYTHM (2009)
Heart failure enhances susceptibility to arrhythmogenic cardiac alternans
Lance D. Wilson et al.
HEART RHYTHM (2009)
Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies
Paola G. Meregalli et al.
HEART RHYTHM (2009)
Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation
Saumya Das et al.
HEART RHYTHM (2009)
Isoform Specificity of the Na/K-ATPase Association and Regulation by Phospholemman
Julie Bossuyt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Patients with Scar-Related Right Ventricular Tachycardia: Determinants of Long-Term Outcome
Adrianus P. Wijnmaalen et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2009)
Functional role of CLC-2 chloride inward rectifier channels in cardiac sinoatrial nodal pacemaker cells
Z. Maggie Huang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Ryanodine receptor and calsequestrin in arrhythmogenesis: What we have learnt from genetic diseases and transgenic mice
Nian Liu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
Norbert Nagy et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
What keeps us ticking: a funny current, a calcium clock, or both?
Edward G. Lakatta et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart
Dayue Duan
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Calcium-activated potassium current: a novel ion channel candidate in atrial fibrillation
Stanley Nattel
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation
Ning Li et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Risk Factors and Mode of Death in Isolated Hypertrophic Cardiomyopathy in Children
Jamie A. Decker et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Mathematical models of the electrical action potential of Purkinje fibre cells
Philip Stewart et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2009)
Na/K-ATPase-An Integral Player in the Adrenergic Fight-or-Flight Response
Donald M. Bers et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2009)
Role of slow delayed rectifier K+-current in QT prolongation in the alloxan-induced diabetic rabbit heart
Cs. Lengyel et al.
ACTA PHYSIOLOGICA (2008)
Expression, localization, and functional properties of Bestrophin 3 channel isolated from mouse heart
Kate E. O'Driscoll et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes:: similarities and differences
Victor A. Maltsev et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)
An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes
Yejia Song et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)
Role of Ca2+-dependent Cl- current on delayed afterdepolarizations.: A simulation study
Julio Gomis-Tena et al.
ANNALS OF BIOMEDICAL ENGINEERING (2008)
Calcium cycling and signaling in cardiac myocytes
Donald M. Bers
ANNUAL REVIEW OF PHYSIOLOGY (2008)
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates
Aman Mahajan et al.
BIOPHYSICAL JOURNAL (2008)
Pathology-specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation
T. Christ et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Diastolic calcium is elevated in metabolic recovery of cardiomyocytes expressing elevated levels of the Na+/H+ exchanger
Istvan Baczko et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2008)
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
Bjoern Christian Schroeder et al.
CELL (2008)
Proarrhythmic Defects in Timothy Syndrome Require Calmodulin Kinase II
William H. Thiel et al.
CIRCULATION (2008)
Calcium-Handling Abnormalities Underlying Atrial Arrhythmogenesis and Contractile Dysfunction in Dogs With Congestive Heart Failure
Yung-Hsin Yeh et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2008)
Functional roles of Na,K-ATPase subunits
Kaethi Geering
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2008)
Inhibition of the Na+/Ca2+ exchanger suppresses torsades de pointes in an intact heart model of long QT syndrome-2 and long QT syndrome-3
Peter Milberg et al.
HEART RHYTHM (2008)
Insulin effects on cardiac Na+/Ca2+ exchanger activity -: Role of the cytoplasmic regulatory loop
Maria Celeste Villa-Abrille et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart
Xiaobin Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome
Michael Brunner et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry
Daniel Fuster et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
Molecular basis of funny current (If) in normal and failing human heart
Francesca Stillitano et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
The Purkinje cell; 2008 style
Wen Dun et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
Spatial relationship between coronary microvascular dysfunction and delayed contrast enhancement in patients with hypertrophic cardiomyopathy
Barbara Sotgia et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels
Lioara Restier et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization
Junko Kurokawa et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation
Takeru Makiyama et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Minimal model for human ventricular action potentials in tissue
Alfonso Bueno-Orovio et al.
JOURNAL OF THEORETICAL BIOLOGY (2008)
Hormonal regulation of cardiac KCNE2 gene expression
Pallob Kundu et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2008)
Increased Ca2+ sparks and sarcoplasmic reticulum Ca2+ stores potentially determine the spontaneous activity of pulmonary vein cardiomyocytes
Sheng-Hsiung Chang et al.
LIFE SCIENCES (2008)
TMEM16A confers receptor-activated calcium-dependent chloride conductance
Young Duk Yang et al.
NATURE (2008)
Genesis and regulation of the heart automaticity
Matteo E. Mangoni et al.
PHYSIOLOGICAL REVIEWS (2008)
Pathophysiology and pharmacology of the cardiac late sodium current
Antonio Zaza et al.
PHARMACOLOGY & THERAPEUTICS (2008)
The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels
Curtis F. Barrett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes
Anna A. Sher et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2008)
Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium
Mary M. Maleckar et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2008)
Role of pacemaking current in cardiac nodes: Insights from a comparative study of sinoatrial node and atrioventricular node
Jie Liu et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2008)
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity
Antonella Caputo et al.
SCIENCE (2008)
Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy
Mark M. Awad et al.
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE (2008)
Characterization of the slowly inactivating sodium current INa2 in canine cardiac single Purkinje cells
L. Bocchi et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Stimulatory action of protein kinase Cε isoform on the slow component of delayed rectifier K+ current in guinea-pig atrial myocytes
H. Toda et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Combined pharmacological block of IKr and IKs increases short-term QT interval variability and provokes torsades de pointes
C. Lengyel et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Selective cardiac plasma-membrane KATP channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion
Szilvia Vajda et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Progesterone regulates cardiac repolarization through a nongenomic pathway - An in vitro patch-clamp and computational modeling study
Hiroaki Nakamura et al.
CIRCULATION (2007)
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval
Alicia Lundby et al.
HEART RHYTHM (2007)
Regulation of systolic [Ca2+]i and cellular Ca2+ flux balance in rat ventricular myocytes by SR Ca2+, L-type Ca2+ current and diastolic [Ca2+]i
K. M. Dibb et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Mechanisms of arrythmogenic cardiac alternans
Lance D. Wilson et al.
EUROPACE (2007)
Photon scattering effects in optical mapping of propagation and arrhythmogenesis in the heart
Martin J. Bishop et al.
JOURNAL OF ELECTROCARDIOLOGY (2007)
The plateau outward current in canine ventricle, sensitive to 4-aminopyridine, is a constitutive contributor to ventricular repolarization
A. Sridhar et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Pacemaker current (lf) in the human sinoatrial node
Arie O. Verkerk et al.
EUROPEAN HEART JOURNAL (2007)
Na+/Ca2+ exchangers:: three mammalian gene families control Ca2+ transport
Jonathan Lytton
BIOCHEMICAL JOURNAL (2007)
Age-related down-regulation of HCN channels in rat sinoatrial node
Xin Huang et al.
BASIC RESEARCH IN CARDIOLOGY (2007)
Genes and atrial fibrillation - A new look at an old problem
Diane Fatkin et al.
CIRCULATION (2007)
Hypertrophic cardiomyopathy and other causes of sudden cardiac death in young competitive athletes, with considerations for preparticipation screening and criteria for disqualification
Barry J. Maron
CARDIOLOGY CLINICS (2007)
Left ventricular hypertrophy in athletes: Morphologic features and clinical correlates
Allen E. Atchley et al.
CARDIOLOGY CLINICS (2007)
How to screen athletes for cardiovascular diseases
Domenico Corrado et al.
CARDIOLOGY CLINICS (2007)
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
Nathalie Gaborit et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: Implication for the gender difference in cardiac arrhythmias
Tetsushi Furukawa et al.
PHARMACOLOGY & THERAPEUTICS (2007)
Functional analysis of Na+/K+-ATPase isoform distribution in rat ventricular myocytes
Sanda Despa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Regulation of Ca2+ and electrical alternans in cardiac myocytes:: role of CAMKII and repolarizing currents
Leonid M. Livshitz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Downregulation of neuronal sodium channel subunits Nav1.1 and Nav1.6 in the sinoatrial node from volume-overloaded heart failure rat
Yuan Du et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle
Jobst-Hendrik Schultz et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Application of blebbistatin as an excitation-contraction uncoupler for electrophysiologic study of rat and rabbit hearts
Vadim V. Fedorov et al.
HEART RHYTHM (2007)
Impact of testosterone on cardiac L-type calcium channels and Ca2+ sparks:: Acute actions antagonize chronic effects
Fikret Er et al.
CELL CALCIUM (2007)
Functional biology of the α2δ subunits of voltage-gated calcium channels
Anthony Davies et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Propagation of the cardiac impulse in the diabetic rat heart: reduced conduction reserve
A. Nygren et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Molecular basis of the T- and L-type Ca2+ currents in canine Purkinje fibres
Barbara Rosati et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Mechanisms of abnormal calcium homeostasis in mutations responsible for catecholaminergic polymorphic ventricular tachycardia
Vivek Iyer et al.
CIRCULATION RESEARCH (2007)
Diabetes mellitus attenuates the repolarization reserve in mammalian heart
Csaba Lengyel et al.
CARDIOVASCULAR RESEARCH (2007)
Comparison of K+ currents in cardiac Purkinje cells isolated from rabbit and dog
Robert Dumaine et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-Segment elevation, short QT intervals, and sudden cardiac death
Charles Antzelevitch et al.
CIRCULATION (2007)
Differential distribution and regulation of mouse cardiac Na+/K+-ATPase α1 and α2 subunits in T-tubule and surface sarcolemmal membranes
Roger G. Berry et al.
CARDIOVASCULAR RESEARCH (2007)
Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome
Hiroshi Morita et al.
HEART RHYTHM (2007)
Dyssynchronous (non-uniform) Ca2+ release in myocytes from streptozotocin-induced diabetic rats
Chun-Hong Shao et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Electrophysiological and arrhythmogenic effects of 5-hydroxytryptamine on human atrial cells are reduced in atrial fibrillation
Davide Pau et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
The promiscuous nature of the cardiac sodium current
V. Haufe et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Arrhythmogenic ion-channel remodeling in the heart: Heart failure, myocardial infarction, and atrial fibrillation
Stanley Nattel et al.
PHYSIOLOGICAL REVIEWS (2007)
Slow delayed rectifier potassium current (I-Ks) and the repolarization reserve
Norbert Jost et al.
ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (2007)
Ionic mechanisms underlying abnormal QT prolongation and the associated arrhythmias in diabetic rabbits: A role of rapid delayed rectifier K+ current
Yiqiang Zhang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2007)
Gender differences in the slow delayed (IKs) but not in inward (IK1) rectifier K+ currents of canine Purkinje fibre cardiac action potential:: key roles for IKs, β-adrenoceptor stimulation, pacing rate and gender
N Abi-Gerges et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels
Stefan Wagner et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Ageing to arrhythmias: conundrums of connections in the ageing heart
Sandra A. Jones
JOURNAL OF PHARMACY AND PHARMACOLOGY (2006)
Effects of sex hormones on ECG parameters and expression of cardiac ion channels in dogs
L. Fulop et al.
ACTA PHYSIOLOGICA (2006)
The heart of trained athletes - Cardiac remodeling and the risks of sports, including sudden death
Barry J. Maron et al.
CIRCULATION (2006)
Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs
Michael J. Riedel et al.
EMBO JOURNAL (2006)
Action potential duration restitution portraits of mammalian ventricular myocytes: Role of calcium current
Elena G. Tolkacheva et al.
BIOPHYSICAL JOURNAL (2006)
Temporal patterns of electrical remodeling in canine ventricular hypertrophy:: Focus on IKs downregulation and blunted β-adrenergic activation
Milan Stengl et al.
CARDIOVASCULAR RESEARCH (2006)
Cardiac alternans do not rely on diastolic sarcoplasmic reticulum calcium content fluctuations
Eckard Picht et al.
CIRCULATION RESEARCH (2006)
Restoring depressed HERG K+ channel function as a mechanism for insulin treatment of abnormal QT prolongation and associated arrhythmias in diabetic rabbits
Yiqiang Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Alternans and spiral breakup in a human ventricular tissue model
K. H. W. J. ten Tusscher et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Gene expression profiling of human cardiac potassium and sodium channels
Balazs Ordog et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2006)
Sex-based transmural differences in cardiac repolarization and ionic-current properties in canine left ventricles
Ling Xiao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Molecular aspects of adrenergic modulation of the transient outward current
Marcel A. G. van der Heyden et al.
CARDIOVASCULAR RESEARCH (2006)
From pulsus to Pulseless the saga of cardiac alternans
James N. Weiss et al.
CIRCULATION RESEARCH (2006)
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model - High-resolution optical mapping study
Takeshi Aiba et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)
Acidic extracellular pH-activated outwardly rectifying chloride current in mammalian cardiac myocytes
S Yamamoto et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Cells expressing unique Na+/Ca2+ exchange (NCX1) splice variants exhibit different susceptibilities to Ca2+ overload
C Hurtado et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Na+/H+ exchangers and the regulation of volume
R. T. Alexander et al.
ACTA PHYSIOLOGICA (2006)
KATP channels as molecular sensors of cellular metabolism
CG Nichols
NATURE (2006)
Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7)
M Tsuboi et al.
HEART RHYTHM (2006)
Whole heart action potential duration restitution properties in cardiac patients: a combined clinical and modelling study
MP Nash et al.
EXPERIMENTAL PHYSIOLOGY (2006)
Actin-dependent regulation of the cardiac Na+/Ca2+ exchanger
M Condrescu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Electrophysiology of pulmonary veins
YJ Chen et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2006)
Long QT syndrome: reduced repolarization reserve and the genetic link
DM Roden
JOURNAL OF INTERNAL MEDICINE (2006)
A multi-modal composition of the late Na+ current in human ventricular cardiomyocytes
VA Maltsev et al.
CARDIOVASCULAR RESEARCH (2006)
The G protein-gated potassium current IK,ACh is constitutively active in patients with chronic atrial fibrillation
D Dobrev et al.
CIRCULATION (2005)
Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish
AD Langenbacher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero
K Hong et al.
CARDIOVASCULAR RESEARCH (2005)
Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle:: underlying molecular, cellular and biophysical mechanisms
SP Patel et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2+ homeostasis in rat heart
N Yaras et al.
DIABETES (2005)
Ca2+-dependent reduction of IK1 in rat ventricular cells:: A novel paradigm for arrhythmia in heart failure?
J Fauconnier et al.
CARDIOVASCULAR RESEARCH (2005)
Genetics of cardiac arrhythmias
AAM Wilde et al.
HEART (2005)
Molecular physiology of cardiac repolarization
JM Nerbonne et al.
PHYSIOLOGICAL REVIEWS (2005)
Nontranscriptional regulation of cardiac repolarization currents by testosterone
CX Bai et al.
CIRCULATION (2005)
Restricting excessive cardiac action potential and QT prolongation -: A vital role for IKs in human ventricular muscle
N Jost et al.
CIRCULATION (2005)
Cardiac repolarization. The long and short of it
C Antzelevitch
EUROPACE (2005)
Transmural gradients in Na/K pump activity and [Na+]i in canine ventricle
J Gao et al.
BIOPHYSICAL JOURNAL (2005)
In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart
S Bendahhou et al.
CARDIOVASCULAR RESEARCH (2005)
Genetics of right ventricular cardiomyopathy
S Sen-Chowdhry et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2005)
Molecular basis of inward rectification: Structural features of the blocker defined by extended polyamine analogs
G Loussouarn et al.
MOLECULAR PHARMACOLOGY (2005)
Three-dimensional electroanatomic voltage mapping increases accuracy of diagnosing arrhythmogenic right ventricular cardiomyopathy/dysplasia
D Corrado et al.
CIRCULATION (2005)
Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model
S Zicha et al.
CARDIOVASCULAR RESEARCH (2005)
A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families
JPP Smits et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2005)
Sudden cardiac death in dogs with remodeled hearts is associated with larger beat-to-beat variability of repolarization
MB Thomsen et al.
BASIC RESEARCH IN CARDIOLOGY (2005)
A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene
SG Priori et al.
CIRCULATION RESEARCH (2005)
Adenovirally delivered shRNA strongly inhibits Na+-Ca2+ exchanger expression but does not prevent contraction of neonatal cardiomyocytes
C Hurtado et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2005)
Autonomic control of cardiac action potentials - Role of potassium channel kinetics in response to sympathetic stimulation
C Terrenoire et al.
CIRCULATION RESEARCH (2005)
Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium
N Szentadrassy et al.
CARDIOVASCULAR RESEARCH (2005)
The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis
AS Dhamoon et al.
HEART RHYTHM (2005)
Spectrum and prognostic significance of arrhythmias on ambulatory Holter electrocardiogram in hypertrophic cardiomyopathy
AS Adabag et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)
Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A
X Ai et al.
CIRCULATION RESEARCH (2005)
Contribution of neuronal sodium channels to the cardiac fast sodium current I-Na is greater in dog heart Purkinje fibers than in ventricles
V Haufe et al.
CARDIOVASCULAR RESEARCH (2005)
Gender-related differences in ventricular myocyte repolarization in the guinea pig
AF James et al.
BASIC RESEARCH IN CARDIOLOGY (2004)
A rapidly activating delayed rectifier K+ current regulates pacemaker activity in adult mouse sinoatrial node cells
RB Clark et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Role of calcium cycling versus restitution in the mechanism of repolarization alternans
EJ Pruvot et al.
CIRCULATION RESEARCH (2004)
A model for human ventricular tissue
KHWJ ten Tusscher et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Sex differences in ventricular repolarization: from cardiac electrophysiology to Torsades de Pointes
N Abi-Gerges et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2004)
Sarcoplasmic reticulum calcium content fluctuation is the key to cardiac alternans
ME Díaz et al.
CIRCULATION RESEARCH (2004)
Delay in right ventricular activation contributes to Brugada syndrome
R Tukkie et al.
CIRCULATION (2004)
Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca2+ overload in cardiac myocytes via modulation of the diastolic membrane potential
I Baczkó et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Linkage between mechanical and electrical alternans in patients with chronic heart failure
M Kodama et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2004)
Electrophysiological changes in heart failure and their relationship to arrhythmogenesis
MJ Janse
CARDIOVASCULAR RESEARCH (2004)
Sudden death associated with short-QT syndrome linked to mutations in HERG
R Brugada et al.
CIRCULATION (2004)
Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy
FG Akar et al.
CIRCULATION RESEARCH (2004)
Atrial ionic remodeling induced by atrial tachycardia in the presence of congestive heart failure
TJ Cha et al.
CIRCULATION (2004)
Computer model of action potential of mouse ventricular myocytes
VE Bondarenko et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts
S Zicha et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
2APB- and JTV519(K201)-sensitive micro Ca2+ waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart
PA Boyden et al.
HEART RHYTHM (2004)
Post-transcriptional alterations in the expression of cardiac Na+ channel subunits in chronic heart failure
S Zicha et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed afterdepolarization in canine heart
ZA Nagy et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium
KM Dibb et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model
TJ Hund et al.
CIRCULATION (2004)
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
YZ Zou et al.
NATURE CELL BIOLOGY (2004)
Arrhythmogenic right ventricular cardiomyopathy: Clinical presentation, diagnosis, and management
S Sen-Chowdhry et al.
AMERICAN JOURNAL OF MEDICINE (2004)
A mathematical treatment of integrated Ca dynamics within the ventricular myocyte
TR Shannon et al.
BIOPHYSICAL JOURNAL (2004)
Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart
S Sharma et al.
FASEB JOURNAL (2004)
Spatial dispersion of action potential duration restitution kinetics is associated with induction of ventricular tachycardia/fibrillation in humans
HN Pak et al.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2004)
Pharmacological modulation of ion channels and transporters
U Ravens et al.
CELL CALCIUM (2004)
Cardiac IKr channels minimally comprise hERG 1a and 1b subunits
EMC Jones et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Role of IKur in controlling action potential shape and contractility in the human atrium -: Influence of chronic atrial fibrillation
E Wettwer et al.
CIRCULATION (2004)
Characterization of a hyperpolarization-activated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium
JR Ehrlich et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Unique Kir2.x properties determine regional and species differences in the cardiac inward rectifier K+ current
AS Dhamoon et al.
CIRCULATION RESEARCH (2004)
Mutation in the KCNQ1 gene leading to the short QT-interval syndrome
C Bellocq et al.
CIRCULATION (2004)
Cav1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
I Splawski et al.
CELL (2004)
Molecular identification and functional roles of a Ca2+-activated K+ channel in human and mouse hearts
YF Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure
FG Akar et al.
CIRCULATION RESEARCH (2003)
Molecular basis of species-specific expression of repolarizing K+ currents in the heart
S Zicha et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Cellular electrophysiology of canine pulmonary vein cardiomyocytes: action potential and ionic current properties
JR Ehrlich et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Ionic remodeling of sinoatrial node cells by heart failure
AO Verkerk et al.
CIRCULATION (2003)
Resting membrane potential regulates Na+-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes
I Baczkó et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy
WS Lin et al.
CIRCULATION (2003)
γ Subunit of voltage-activated calcium channels
MG Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Effects of aging on cardiovascular responses to parasympathetic withdrawal
JR Stratton et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
Probing the contribution of IKs to canine ventricular repolarization -: Key role for β-adrenergic receptor stimulation
PGA Volders et al.
CIRCULATION (2003)
Effects of the enantiomers of BayK 8644 on the charge movement of L-type Ca channels in guinea-pig ventricular myocytes
P Artigas et al.
JOURNAL OF MEMBRANE BIOLOGY (2003)
Non-equilibrium Gating in cardiac Na+ channels -: An original mechanism of arrhythmia
CE Clancy et al.
CIRCULATION (2003)
Hypertrophic cardiomyopathy - Distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy
P Richard et al.
CIRCULATION (2003)
Functional role of L-type Cav13Ca2+ channels in cardiac pacemaker activity
ME Mangoni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Effects of the chromanol HMR 1556 on potassium currents in atrial myocytes
RF Bosch et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2003)
Nonuniform Ca2+ transients in arrhythmogenic Purkinje cells that survive in the infarcted canine heart
PA Boyden et al.
CARDIOVASCULAR RESEARCH (2003)
Effects of chromanol 293B on transient outward and ultra-rapid delayed rectifier potassium currents in human atrial myocytes
XL Du et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2003)
A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy:: Modulation by dietary fat content
BN Finck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
KCNQ1 gain-of-function mutation in familial atrial fibrillation
YH Chen et al.
SCIENCE (2003)
In vivo androgen treatment shortens the QT interval and increases the densities of inward and delayed rectifier potassium currents in orchiectomized male rabbits
XK Liu et al.
CARDIOVASCULAR RESEARCH (2003)
Electrical remodeling of the epicardial border zone in the canine infarcted heart: a computational analysis
C Cabo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Characteristics of single cells isolated from the atrioventricular node of the adult guinea-pig heart.
KH Yuill et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2002)
Properties of potassium currents in Purkinje cells of failing human hearts
W Han et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Two-pore domain K+ channels -: molecular sensors
AD O'Connell et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2002)
Gating of the late Na+ channel in normal and failing human myocardium
AI Undrovinas et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males
JM Di Diego et al.
CIRCULATION (2002)
Transmural action potential and ionic current remodeling in ventricles of failing canine hearts
GR Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Contribution of IK,ADO tothe negative drornotropic effect of adenosine
AE Martynyuk et al.
BASIC RESEARCH IN CARDIOLOGY (2002)
An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart
SKG Maier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The vitelliform macular dystrophy protein defines a new family of chloride channels
H Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Modulation of Ca2+ release in cardiac myocytes by changes in repolarization rate -: Role of phase-1 action potential repolarization in excitation-contraction coupling
R Sah et al.
CIRCULATION RESEARCH (2002)
A calcium sensor in the sodium channel modulates cardiac excitability
HL Tan et al.
NATURE (2002)
Effects of thyroid hormone on the arrhythmogenic activity of pulmonary vein cardiomyocytes
YC Chen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)
Involvement of the cardiac ryanodine receptor/calcium release channel in catecholaminergic polymorphic ventricular tachycardia
AR Marks et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
Role of the 293b-sensitive, slowly activating delayed rectifier potassium current, i(Ks), in pacemaker activity of rabbit isolated sino-atrial node cells
M Lei et al.
CARDIOVASCULAR RESEARCH (2002)
Real time, confocal imaging of Ca2+ waves in arterially perfused rat hearts
AP Baader et al.
CARDIOVASCULAR RESEARCH (2002)
Alterations in properties of L-type Ca channels in aging rat heart
IR Josephson et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Cellular mechanisms underlying the long QT syndrome
C Antzelevitch et al.
CURRENT OPINION IN CARDIOLOGY (2002)
Effects of rapid atrial pacing on the arrhythmogenic activity of single cardiomyocytes from pulmonary veins - Implication in initiation of atrial fibrillation
YJ Chen et al.
CIRCULATION (2001)
Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery
PE Light et al.
FASEB JOURNAL (2001)
Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts
AO Verkerk et al.
CIRCULATION (2001)
Genetic manipulation of cardiac K+ channel function in mice -: What have we learned, and where do we go from here?
JM Nerbonne et al.
CIRCULATION RESEARCH (2001)
Ionic remodeling of cardiac Purkinje cells by congestive heart failure
W Han et al.
CIRCULATION (2001)
Electrophysiology of the sodium-potassium-ATPase in cardiac cells
HG Glitsch
PHYSIOLOGICAL REVIEWS (2001)
Depressed levels of Ca2+-cycling proteins may underlie sarcoplasmic reticulum dysfunction in the diabetic heart
T Netticadan et al.
DIABETES (2001)
Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle
AC Zygmunt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure
CA Ufret-Vincenty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation
MJ Mihm et al.
CIRCULATION (2001)
Glibenclamide effects on reperfusion-induced malignant arrhythmias and left ventricular mechanical recovery from stunning in conscious sheep
HF del Valle et al.
CARDIOVASCULAR RESEARCH (2001)
Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers
TX Pang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Frequency-dependent electrophysiological effect of ibutilide on human atrium and ventricle
N Oshikawa et al.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2001)
Slow delayed rectifier current and repolarization in canine cardiac Purkinje cells
W Han et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
The properties of the pacemaker current IF in human ventricular myocytes are modulated by cardiac disease
E Cerbai et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Altered connexin expression in human congestive heart failure
E Dupont et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Effects of sex and age on electrocardiographic and cardiac electrophysiological properties in adults
T Taneja et al.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY (2001)
Inhibition of IKs channels by HMR 1556
H Gögelein et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2000)
Loss of the normal epicardial to endocardial gradient of cftr mRNA expression in the hypertrophied rabbit left ventricle
KR Wong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Effects of endothelin-1 on calcium and potassium currents in undiseased human ventricular myocytes
J Magyar et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2000)
A common polymorphism associated with antibiotic-induced cardiac arrhythmia
F Sesti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Expression of T- and L-type calcium channel mRNA in murine sinoatrial node
G Bohn et al.
FEBS LETTERS (2000)
A comparison of transient outward currents in canine cardiac Purkinje cells and ventricular myocytes
W Han et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
Intracellular pH regulation by Na+/H+ exchange requires phosphatidylinositol 4,5-bisphosphate
O Aharonovitz et al.
JOURNAL OF CELL BIOLOGY (2000)
Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node
H Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
Effects of antiarrhythmic drugs on cloned cardiac voltage-gated potassium channels expressed in Xenopus oocytes
S Rolf et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2000)
Antiarrhythmics - from cell to clinic: past, present, and future
JC Hancox et al.
HEART (2000)
Effects of experimental heart failure on atrial cellular and ionic electrophysiology
DS Li et al.
CIRCULATION (2000)
Preventing ventricular fibrillation by flattening cardiac restitution
A Garfinkel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Intracellular Ca2+ release contributes to automaticity in cat atrial pacemaker cells
J Hüser et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
INaCa contributes to electrical heterogeneity within the canine ventricle
AC Zygmunt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
A novel topology model of the human Na+/H+ exchanger isoform 1
S Wakabayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Properties of the delayed rectifier potassium current in porcine sino-atrial node cells
K Ono et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
A novel anionic inward rectifier in native cardiac myocytes
D Duan et al.
CIRCULATION RESEARCH (2000)
Interaction of PIP2 with the XIP region of the cardiac Na/Ca exchanger
ZP He et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)
The role of the delayed rectifier component IKs in dog ventricular muscle and Purkinje fibre repolarization
A Varró et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
Voltage-dependent stimulation of the Na+-K+ pump by insulin in rabbit cardiac myocytes
PS Hansen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)
Idiopathic short QT interval: A new clinical syndrome?
I Gussak et al.
CARDIOLOGY (2000)
Share Paper
