4.1 Article

Tricuspid Valve Repair at Pulmonary Valve Replacement in Repaired Tetralogy of Fallot

Journal

PEDIATRIC CARDIOLOGY
Volume 43, Issue 1, Pages 74-81

Publisher

SPRINGER
DOI: 10.1007/s00246-021-02694-y

Keywords

Tricuspid valve regurgitation; Pulmonary valve replacement; Congenital heart disease; Tetralogy of Fallot; Valvular diseases

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The study retrospectively reviewed the clinical records of TOF patients who underwent PVR between 2001 and 2012, finding that concomitant TVP can effectively improve TR and RVEDVi, but may not prevent the recurrence of TR when PV failure occurs. Concomitant TVP can effectively preserve tricuspid valve function until PV failure.
Background Pulmonary valve replacement (PVR) is often performed in patients with repaired tetralogy of Fallot (TOF). Concomitant tricuspid valvuloplasty (TVP) in those with tricuspid regurgitation (TR) at the time of PVR is still controversial. Method We retrospectively reviewed clinical records of patients who underwent PVR between 2001 and 2012. We analyzed the impact of concomitant TVP on the tricuspid valve function and right ventricle function and size in mid-term. Results 119 patients with mild to moderate TR at the time of PVR were enrolled. 33 patients underwent concomitant TVP (TVP group) and 86 patients underwent PVR alone (no-TVP group). There was a significant reduction of TR (p < 0.001) and right ventricular end-diastolic volume index (RVEDVi) (p < 0.001). However, in patients who showed prosthetic pulmonary valve (PV) failure at the last follow-up, there was no significant decrease in TR regardless of concomitant TVP. In the patients with preserved prosthetic PV function, TR was significantly improved (p < 0.001 in both groups). The multivariable analysis showed that significant risk factors for recurrence of significant TR were preoperative moderate TR and prosthetic PV failure. Conclusions After PVR in repaired TOF patients, there was an improvement in the degree of TR and the RVEDVi. Concomitant TVP at the time of PVR may not be able to prevent the recurrence of TR when prosthetic PV failure occurs; however, it may effectively preserve tricuspid valve function until that time.

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