4.1 Article

Adrenal suppression from exogenous glucocorticoids: Recognizing risk factors and preventing morbidity

Journal

PAEDIATRICS & CHILD HEALTH
Volume 26, Issue 4, Pages 242-247

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/pch/pxab015

Keywords

Adrenal insufficiency; Adrenal suppression; Glucocorticoids; Inhaled corticosteroids

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Recognizing symptoms and risk factors of adrenal suppression, as well as familiarizing with potential strategies to reduce associated risks, are crucial starting points for clinicians prescribing glucocorticoids.
Adrenal suppression (AS), a potential side effect of glucocorticoid therapy (including inhaled corticosteroids), can be associated with significant morbidity and even death. In Canada, adrenal crisis secondary to AS continues to be reported in children. Being aware of symptoms associated with AS, understanding the risk factors for developing this condition, and familiarity with potential strategies to reduce risks associated with AS, are essential starting points for any clinician prescribing glucocorticoids.

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