4.3 Review

Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases

Related references

Note: Only part of the references are listed.
Editorial Material Cell Biology

Senescence and extracellular vesicles: novel partners in vascular amyloidosis

Meredith Whitehead et al.

AGING-US (2023)

Article Neurosciences

Exosome-mediated delivery of antisense oligonucleotides targeting alpha-synuclein ameliorates the pathology in a mouse model of Parkinson's disease

Jiaolong Yang et al.

Summary: This study demonstrated that exosome-mediated delivery of ASO4 could effectively reduce alpha-synuclein expression, attenuate its aggregation, and improve locomotor functions in a transgenic model of Parkinson's disease.

NEUROBIOLOGY OF DISEASE (2021)

Article Neurosciences

Serum Exosome MicroRNAs Predict Multiple Sclerosis Disease Activity after Fingolimod Treatment

Saeideh Ebrahimkhani et al.

MOLECULAR NEUROBIOLOGY (2020)

Article Biochemistry & Molecular Biology

Astrocyte-Derived Exosomal microRNA miR-200a-3p Prevents MPP+-Induced Apoptotic Cell Death Through Down-Regulation of MKK4

Norshalena Shakespear et al.

NEUROCHEMICAL RESEARCH (2020)

Review Chemistry, Multidisciplinary

Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders

Raghavendra Upadhya et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Neurosciences

Astrocytes Protect Human Dopaminergic Neurons from α-Synuclein Accumulation and Propagation

Taiji Tsunemi et al.

JOURNAL OF NEUROSCIENCE (2020)

Review Medicine, General & Internal

Exosomes from Human Periapical Cyst-MSCs: Theranostic Application in Parkinson's Disease

Marco Tatullo et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2020)

Article Biochemistry & Molecular Biology

Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein

Dilshan S. Harischandra et al.

SCIENCE SIGNALING (2019)

Article Cell Biology

Microglia as modulators of exosomal alpha-synuclein transmission

Yun Xia et al.

CELL DEATH & DISEASE (2019)

Review Neurosciences

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

Archana Prasad et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)

Article Medicine, Research & Experimental

ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia

William R. Swindell et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2019)

Review Medicine, Research & Experimental

Exosomes in Pathogenesis, Diagnosis, and Treatment of Alzheimer's Disease

Liqun Jiang et al.

MEDICAL SCIENCE MONITOR (2019)

Article Multidisciplinary Sciences

Exosomes regulate neurogenesis and circuit assembly

Pranav Sharma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

BIN1 favors the spreading of Tau via extracellular vesicles

Andrea Crotti et al.

SCIENTIFIC REPORTS (2019)

Review Immunology

The multiple roles of exosomes in Parkinson's disease: an overview

Chiara Porro et al.

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2019)

Review Clinical Neurology

Multiple sclerosis - a review

R. Dobson et al.

EUROPEAN JOURNAL OF NEUROLOGY (2019)

Article Neurosciences

Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

Charisse N. Winston et al.

JOURNAL OF ALZHEIMERS DISEASE (2019)

Review Neurosciences

Diversity and Specificity of Astrocyte-neuron Communication

Caitlin A. Durkee et al.

NEUROSCIENCE (2019)

Review Clinical Neurology

α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease

Zachary A. Sorrentino et al.

ACTA NEUROPATHOLOGICA (2019)

Review Clinical Neurology

Alzheimer's disease

C. A. Lane et al.

EUROPEAN JOURNAL OF NEUROLOGY (2018)

Article Clinical Neurology

Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

Maitrayee Sardar Sinha et al.

ACTA NEUROPATHOLOGICA (2018)

Article Clinical Neurology

High complement levels in astrocyte-derived exosomes of Alzheimer disease

Edward J. Goetzl et al.

ANNALS OF NEUROLOGY (2018)

Article Pharmacology & Pharmacy

Microglia-derived extracellular vesicles in Alzheimer's Disease: A double-edged sword

Teresa Trotta et al.

BIOCHEMICAL PHARMACOLOGY (2018)

Review Clinical Neurology

C9orf72-mediated ALS and FTD: multiple pathways to disease

Rubika Balendra et al.

NATURE REVIEWS NEUROLOGY (2018)

Review Neurosciences

Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer's Disease

Edwin E. Reza-Zaldivar et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Article Biochemistry & Molecular Biology

Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose

Francesca Massenzio et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)

Article Biochemistry & Molecular Biology

Amyloid precursor protein products concentrate in a subset of exosomes specifically endocytosed by neurons

Karine Laulagnier et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Neurosciences

Exosomes in Parkinson's Disease

Xiaoqing Wu et al.

NEUROSCIENCE BULLETIN (2017)

Article Neurosciences

The release and trans-synaptic transmission of Tau via exosomes

Yipeng Wang et al.

MOLECULAR NEURODEGENERATION (2017)

Review Pharmacology & Pharmacy

Exosomes: Therapy delivery tools and biomarkers of diseases

Lucio Barile et al.

PHARMACOLOGY & THERAPEUTICS (2017)

Article Geriatrics & Gerontology

Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer's Disease

Tingting Zheng et al.

FRONTIERS IN AGING NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

Exosomal microRNA signatures in multiple sclerosis reflect disease status

Saeideh Ebrahimkhani et al.

SCIENTIFIC REPORTS (2017)

Review Biochemistry & Molecular Biology

The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis

Maya A. Hanspal et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)

Article Clinical Neurology

Exosome-Based Delivery of miR-124 in a Huntington's Disease Model

Soon-Tae Lee et al.

JOURNAL OF MOVEMENT DISORDERS (2017)

Article Biochemistry & Molecular Biology

Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS

Marisa Kamelgarn et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)

Article Clinical Neurology

Exosome secretion is a key pathway for clearance of pathological TDP-43

Yohei Iguchi et al.

BRAIN (2016)

Editorial Material Cell Biology

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

Erik R. Abels et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)

Article Biochemistry & Molecular Biology

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease

Edward J. Goetzl et al.

FASEB JOURNAL (2016)

Article Biochemistry & Molecular Biology

Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease

Edward J. Goetzl et al.

FASEB JOURNAL (2016)

Review Biochemistry & Molecular Biology

Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease

Laura J. Vella et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Biotechnology & Applied Microbiology

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing

Marie-Cecile Didiot et al.

MOLECULAR THERAPY (2016)

Review Biochemistry & Molecular Biology

Exosomes in Alzheimer's disease

Tarja Malm et al.

NEUROCHEMISTRY INTERNATIONAL (2016)

Article Clinical Neurology

Epidemiology of Multiple Sclerosis

Jonathan Howard et al.

NEUROLOGIC CLINICS (2016)

Article Cell Biology

Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD

Thomas Westergard et al.

CELL REPORTS (2016)

Article Cell Biology

TDP-43 is intercellularly transmitted across axon terminals

Marisa S. Feiler et al.

JOURNAL OF CELL BIOLOGY (2015)

Article Chemistry, Multidisciplinary

Exosomes as drug delivery vehicles for Parkinson's disease therapy

Matthew J. Haney et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Article Medicine, General & Internal

Parkinson's disease

Lorraine V. Kalia et al.

LANCET (2015)

Article Neurosciences

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

Hirohide Asai et al.

NATURE NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia

Insaf Bahrini et al.

SCIENTIFIC REPORTS (2015)

Article Biochemistry & Molecular Biology

A potential function for neuronal exosomes: Sequestering intracerebral amyloid-β peptide

Kohei Yuyama et al.

FEBS LETTERS (2015)

Article Biochemistry & Molecular Biology

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

Stephanie M. Y. Kong et al.

HUMAN MOLECULAR GENETICS (2014)

Article Multidisciplinary Sciences

Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms

Leslie I. Grad et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Biochemistry & Molecular Biology

The hallmarks of Parkinson's disease

Paul M. A. Antony et al.

FEBS JOURNAL (2013)

Article Biochemistry & Molecular Biology

Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

Lydie Morel et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Cell Biology

Extracellular vesicles: Exosomes, microvesicles, and friends

Graca Raposo et al.

JOURNAL OF CELL BIOLOGY (2013)

Review Multidisciplinary Sciences

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

Mathias Jucker et al.

NATURE (2013)

Article Cell Biology

Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains

Takashi Nonaka et al.

CELL REPORTS (2013)

Review Clinical Neurology

Huntington's disease

Ainhi D. Ha et al.

CURRENT OPINION IN NEUROLOGY (2012)

Article Neurosciences

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Karin M. Danzer et al.

MOLECULAR NEURODEGENERATION (2012)

Review Physiology

Emerging role of neuronal exosomes in the central nervous system

Mathilde Chivet et al.

FRONTIERS IN PHYSIOLOGY (2012)

Review Physiology

Emerging roles of exosomes in neuron-glia communication

Carsten Fruehbeis et al.

FRONTIERS IN PHYSIOLOGY (2012)

Review Physiology

Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

Shayne A. Bellingham et al.

FRONTIERS IN PHYSIOLOGY (2012)

Article Neurosciences

Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity

Gaelle Lachenal et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2011)

Article Medicine, General & Internal

Amyotrophic lateral sclerosis

Matthew C. Kiernan et al.

LANCET (2011)

Article Neurosciences

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

Lydia Alvarez-Erviti et al.

NEUROBIOLOGY OF DISEASE (2011)

Article Medicine, Research & Experimental

Neuropathological Alterations in Alzheimer Disease

Alberto Serrano-Pozo et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)

Review Clinical Neurology

Microglia in neurodegenerative disease

V. Hugh Perry et al.

NATURE REVIEWS NEUROLOGY (2010)

Article Multidisciplinary Sciences

Alzheimer's disease β-amyloid peptides are released in association with exosomes

Lawrence Rajendran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Multidisciplinary Sciences

Lewy bodies

CW Shults

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Geriatrics & Gerontology

Staging of brain pathology related to sporadic Parkinson's disease

H Braak et al.

NEUROBIOLOGY OF AGING (2003)