High-Throughput Electrochemistry: State of the Art, Challenges, and Perspective

Electrochemical transformations involve complex parameter interactions, ranging from universal chemistry variables such as solvent and reagents to specialist factors including electrode material and current density. Hence, the development of a robust and scale-independent electrochemical reaction can currently be a challenge. High-throughput experimentation (HTE) is an enabling method for reaction optimization and robustness testing. Here we provide an industrial and academic perspective on the state of the art of the combination of HTE with electrochemical reaction optimization for applications, including scale-up. We then present our vision for a future in which HTE reduces barriers to wide adoption of electrochemistry across the field of chemical synthesis.

Automated summary

Electrochemical transformations involve complex interactions among various parameters, posing a challenge in developing robust and scale-independent reactions. High-throughput experimentation is a useful method for optimizing reactions and testing their robustness.