Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 25, Issue 10, Pages 2221-2229Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.oprd.1c00245
Keywords
photochemical reaction technology; Monte Carlo; scale-up; CapEx; LED
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This paper presents recent innovation activities related to the implementation of LED-based photochemical reaction technology at kilolab and production scales, and investigates the capital expenditure uncertainty estimation of photochemical lamps, finding it to be within 15-30% at two standard deviations.
The purpose of this paper is twofold: it presents recent innovation activities related to the implementation of LEDbased photochemical reaction technology at kilolab (20 L) and production (1000 L) scales at Syngenta Crop Protection AG in Munchwilen, Switzerland, and investigates the capital expenditure (CapEx) uncertainty estimation of photochemical lamps using Monte Carlo analysis. It was found that for the reaction system considered in this paper, depending on the photon rate measurement method.actinometry or radiometry.the CapEx uncertainty is expected to be within 15-30% at two standard deviations.
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