Journal
ORGANIC LETTERS
Volume 23, Issue 11, Pages 4441-4446Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.1c01375
Keywords
-
Categories
Funding
- University of Bologna [2017W8KNZW]
- MIUR [PRIN 2017 2017E44A9P]
Ask authors/readers for more resources
The study documents a visible-light photoredox/[Co(III)] cocatalyzed dehydrogenative functionalization of cyclic and acyclic styryl derivatives with carboxylic acids, leading to chemo- and regioselective allylic functionalization of styryl compounds, yielding allylic carboxylates. Both intermolecular and intramolecular variants are achieved in high yields, with a proposed mechanistic rationale based on experimental and spectroscopic investigation.
The visible-light photoredox/[Co(III)] cocatalyzed dehydrogenative functionalization of cyclic and acyclic styryl derivatives with carboxylic acids is documented. The methodology enables the chemo- and regioselective allylic functionalization of styryl compounds, leading to allylic carboxylates (32 examples) under stoichiometric acceptorless conditions. Intermolecular as well as intramolecular variants are documented in high yields (up to 82%). A mechanistic rationale is also proposed on the basis of a combined experimental and spectroscopic investigation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available