Synthesis of Structurally Diverse Allylsilanes via Copper-Catalyzed Regiodivergent Hydrosilylation of 1,3-Dienes

Unprecedented copper-catalyzed regiodivergent hydrosilylation reactions of substituted 1,3-dienes with hydrosilanes have been developed. The 1,2- and 1,4-hydrosilylations of 1-(hetero)aryl-substituted 1,3-dienes were highly selectively controlled via variation of the catalytic systems. Meanwhile, the 1,4-hydrosilylation reaction of 2-aryl-substituted 1,3-dienes with diphenylsilane was also successfully realized for the first time. These methods provide convenient and efficient approaches for the synthesis of structurally diverse allylsilanes.

Automated summary

Novel copper-catalyzed regiodivergent hydrosilylation reactions have been developed, allowing highly selective control of 1,2- and 1,4-hydrosilylation reactions of substituted 1,3-dienes by varying the catalytic systems. Additionally, the first successful 1,4-hydrosilylation reaction of 2-aryl-substituted 1,3-dienes with diphenylsilane was achieved, providing convenient and efficient methods for synthesizing structurally diverse allylsilanes.